(3R)-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

This is the question of (3R) -2- (tert-butoxycarbonyl) -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid ester. To clarify its chemical structure, let me explain it in detail.
In this compound, the core structure is 1,2,3,4-tetrahydroisoquinoline. Isoquinoline is a nitrogen-containing heterocyclic aromatic hydrocarbon, and here it is hydrogenated into a tetrahydro state. This structure is quite common in many natural products and drug molecules, giving the compound a specific spatial configuration and electronic properties.
At 3 positions, there is a monocarboxyl ester structure, that is, -3-carboxylate. The existence of ester groups can affect the solubility, stability and reactivity of compounds. In organic synthesis and pharmaceutical chemistry, it is often used as a reaction check point or modified group to facilitate subsequent derivatization operations.
is particularly critical, and the 2-position connection (tert-butoxycarbonyl) is - (tert-butoxycarbonyl). Tert-butoxycarbonyl is a commonly used amino protecting group. When synthesizing polypeptides and complex organic molecules, it can effectively protect the amino group and prevent it from participating in the reaction for no reason during the reaction. When appropriate, it can be gently removed to restore the amino activity. The connection to the second position of tetrahydroisoquinoline here affects the overall charge distribution and steric resistance of the molecule, and has a great impact on its physicochemical properties and biological activities.
As for its three-dimensional configuration, the carbon atom configuration at the third position is marked by (3R) as R-type. This stereochemical characteristic often plays a decisive role in drugs and bioactive molecules. Different configurations may exhibit very different biological activities, metabolic pathways and toxicity.
In summary, (3R) -2- (tert-butoxycarbonyl) -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid esters are composed of specific heterocycles, protective groups and ester groups. The interaction of each part determines the unique properties and potential uses of the compound.

(3R) 2- (tert -butoxycarbonyl) -1, 2, 3, 4 -tetrahydroisoquinoline -3 -carboxylate are important compounds in the field of organic synthesis. Their main uses involve many fields such as pharmaceutical chemistry and total synthesis of natural products.
In the field of medicinal chemistry, such compounds are often key intermediates for creating biologically active drug molecules. Due to their structural properties, they can participate in a variety of chemical reactions, helping to build complex drug frameworks, and then develop therapeutic drugs for specific diseases.
In the total synthesis of natural products, (3R) -2- (tert -butoxycarbonyl) -1, 2, 3, 4 -tetrahydroisoquinoline -3 -carboxylate can be used as an important building block. With its chiral center and specific functional groups, it precisely constructs structures similar to natural products, laying the foundation for in-depth research on the biological activity and mechanism of action of natural products.
In addition, in the field of materials science, through structural modification and derivatization, it may be possible to develop organic materials with special properties, such as optoelectronic materials, etc., which show potential application value in electronic devices, optical displays, etc.
In summary, (3R) -2- (tert -butoxycarbonyl) -1,2,3,4 -tetrahydroisoquinoline -3 -carboxylate is indispensable in many scientific research and industrial production fields due to its unique structure and reactivity, and is of great significance to promote the development of related fields.

(3R) 2- (tert -butoxycarbonyl) -1,2,3,4 -tetrahydroisoquinoline -3 -carboxylate is an organic compound, and the synthesis method is quite complicated.
One method is to use suitable starting materials and react through multiple steps. Initially, an aromatic compound with a specific structure is selected and condensed with a nitrogen-containing reagent under suitable reaction conditions. This process requires strict control of the reaction temperature, time and proportion of reactants to promote the formation of key nitrogen-containing intermediates.
Subsequently, a protective group introduction step is performed on the intermediate, and the tert -butoxycarbonyl protective group is introduced to a specific nitrogen atom. The introduction of this protecting group can ensure that the chemical environment of the nitrogen atom is stable in the subsequent reaction and avoid unnecessary side reactions.
Furthermore, carboxylation is carried out at another key position. This step requires the selection of an appropriate carboxylation reagent and the presence of a suitable catalyst to proceed smoothly to obtain an intermediate product containing carboxyl groups.
Subsequently, the intermediate product is cyclized to construct the parent nuclear structure of 1, 2, 3, 4 -tetrahydroisoquinoline. The conditions of this cyclization reaction are also extremely critical. The choice of temperature, solvent and catalyst all have a significant impact on the yield of the reaction and the stereochemical structure of the product. < Br >
After various reaction steps, and through careful separation and purification operations, the final product can be obtained from (3R) -2- (tert -butoxycarbonyl) -1, 2, 3, 4 -tetrahydroisoquinoline -3 -carboxylate. However, each step of the reaction needs to be carefully controlled, and it is difficult to obtain the expected product with a slight poor pool.

(3R) -2- (tert-butoxycarbonyl) -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid ester is one of the organic compounds. This compound has specific physical properties, let me tell you one by one.
Looking at its properties, under normal temperature and pressure, it is mostly white to quasi-white solid, which is a significant sign of its appearance.
Talking about the melting point, due to the interaction between atoms and chemical bonds in the molecular structure, it has a relatively definite melting point range, which is between [X] ℃ - [X] ℃. This melting point value is of great significance for its identification and purity determination.
Re-discussion of solubility, this compound exhibits certain solubility properties in organic solvents. In halogenated hydrocarbon organic solvents such as dichloromethane and chloroform, it exhibits good solubility. This is due to the formation of appropriate intermolecular forces between halogenated hydrocarbon molecules and the compound molecules, such as van der Waals forces, dipole-dipole interactions, etc., so it can be miscible. However, in water, the solubility is poor. Due to the large proportion of hydrophobic groups in its molecular structure, the ability to form hydrogen bonds with water molecules is weak, making it difficult to dissolve in water.
As for the density, it has been determined to be about [X] g/cm ³. This density value is determined by the molecular mass and the degree of close arrangement of molecules in solid or liquid state, reflecting the mass characteristics of the substance per unit volume. In related chemical production and experimental operations, the precise control of material quantity is of great significance.
(3R) -2 - (tert-butoxycarbonyl) -1,2,3,4-tetrahydroisoquinoline-3-carboxylate The physical properties of tetrahydroisoquinoline-3-carboxylic acid esters are of critical significance in many fields such as organic synthesis and pharmaceutical chemistry, laying an important foundation for their application and research.

I don't know the price range of (3R) -2- (tert-butoxycarbonyl) -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid ester in the market. This compound is not widely known and commonly used, and its price is affected by many factors.
First, the purity has a great impact. If it is high purity, it is suitable for fine scientific research, and the price must be high; if the purity is slightly lower, it is used for general experiments, and the price may be slightly reduced. Second, the difficulty of preparation is related to the price. If the synthesis steps are complicated, the conditions are harsh, and the raw materials are rare, the cost will increase and the price will be expensive. Third, market supply and demand are also key. If there is more demand and less supply, the price will rise; on the contrary, if the supply exceeds the demand, the price may decline.
However, I do not know the detailed market situation of this compound, so it is difficult to determine the price range. To know the price, you can consult the chemical reagent supplier, or check it on the chemical product trading platform, so that you can get a close price range.