3 Quinolinecarboxylic Acid 4 Trifluoromethyl
quinoline thiophene imidazole thiazole

3-Quinolinecarboxylic acid, 4-(trifluoromethyl)-

Taiy Chemical

    Specifications

    HS Code

    772551

    Chemical Formula C11H6F3NO2
    Molecular Weight 241.17
    Appearance Solid (predicted)
    Boiling Point 352.3°C at 760 mmHg (predicted)
    Melting Point 197 - 200°C
    Density 1.493 g/cm³ (predicted)
    Logp 3.23 (predicted)
    Solubility Soluble in DMSO, sparingly soluble in water
    Pka 2.47 (predicted)
    Refractive Index 1.565 (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 3-Quinolinecarboxylic acid, 4-(trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3 - Quinolinecarboxylic acid, 4- (trifluoromethyl) -
    4- (trifluoromethyl) -3 -quinolinecarboxylic acid, which has a wide range of uses. In the field of medicine, it is a key organic synthesis intermediate, and the preparation of many new quinolone antibacterial drugs depends on it. Quinolone antibacterial drugs have the characteristics of wide antibacterial spectrum and strong activity, and have a significant inhibitory effect on Gram-positive and negative bacteria. They are often used in clinical practice for the treatment of respiratory tract, urinary tract, intestinal tract and other infectious diseases. Therefore, 4- (trifluoromethyl) -3 -quinolinecarboxylic acid is of great significance in the development and production of medicine.
    In the field of pesticides, it also plays an important role. A variety of high-efficiency and low-toxicity pesticide varieties can be prepared by chemical modification and transformation. Such pesticides have good pest control effects, can effectively protect crops from pests and diseases, improve crop yield and quality, and contribute greatly to the sustainable development of agriculture.
    Furthermore, in the field of materials science, 4- (trifluoromethyl) -3-quinoline carboxylic acids and their derivatives have emerged in the research and development of new functional materials due to their unique chemical structures and properties. Or can be used to prepare optical materials, electronic materials, etc., providing new opportunities for the innovative development of materials science. From this perspective, 4- (trifluoromethyl) -3 -quinoline carboxylic acid, with its various uses, plays an important role in many fields such as medicine, pesticides, materials, etc., and promotes the progress and development of technology in various fields.
    What are the physical properties of 3 - Quinolinecarboxylic acid, 4- (trifluoromethyl) -
    4- (trifluoromethyl) -3 -quinolinecarboxylic acid, this material has a specific property and is unique among all chemicals. Its color may be pure white, like the first fall of winter snow, and the texture is as fine as powder. It often survives in the form of crystals, and the crystal shape is neat, just like heaven.
    Looking at its melting point, the melting point is very clear, just like the instruction of a specific temperature. At this point, it gradually melts from a solid state to a flexible liquid state, just like melting ice and melting snow, and flows freely. The boiling point is like another temperature mark. At this high temperature, the liquid leaps into a gaseous state and escapes into an invisible environment.
    Solubility is also an important physical property. In water, its dissolution state is limited, such as stones thrown into a shallow stream, which is difficult to melt and can only be slightly dissolved. However, in the realm of organic solvents, such as ethanol, ether, etc., its solubility has been greatly improved, just like fish getting water, the amount of solubility has increased significantly, and it can be fused with solvents.
    Furthermore, its density state, compared with water, is either heavy or light, which is a manifestation of its characteristics. The value of density is like the weight of a thing, revealing the proportion of its mass in space. In terms of stability, under normal temperature and pressure, it is like a stable old man, with stable properties and not easy to change. However, under special conditions, such as high temperature hot topic and strong acid and alkali environment, its structure may change, and its properties will also change accordingly, just like when the situation changes, everything is disturbed by it. These physical properties are the unique imprints of 4- (trifluoromethyl) -3-quinoline carboxylic acids, which lay the foundation for exploration and application in the field of chemistry.
    What is the chemical synthesis method of 3 - Quinolinecarboxylic acid, 4- (trifluoromethyl) -
    The synthesis of 4- (trifluoromethyl) -3 -quinoline carboxylic acid is an important topic in the field of chemical synthesis. This compound is widely used in many fields such as medicine and pesticides. According to the ancient method, the synthesis method is described in detail.
    First take the appropriate quinoline derivative as the starting material, which often has a specific substituent, which lays the foundation for the subsequent reaction. In the reaction system, add reagents containing trifluoromethyl, which can effectively introduce trifluoromethyl groups. The reaction needs to be carried out under suitable reaction conditions, such as temperature, pressure, and the choice of solvent, which all have a great influence on the reaction process and product yield. < Br >
    Generally speaking, the reaction temperature should be precisely controlled. If it is too high, the side reactions will increase, and if it is too low, the reaction rate will be delayed. The choice of solvent should not be ignored, and those that can dissolve the reactants and have no adverse effects on the reaction should be selected. Common organic solvents such as toluene and dichloromethane can be selected according to the reaction characteristics.
    In the reaction process, various reaction mechanisms such as nucleophilic substitution and electrophilic substitution are involved. By ingeniously designing the reaction steps, the reagent containing trifluoromethyl reacts with the quinoline derivative at a specific position, and the target molecular structure is gradually constructed.
    After the reaction is completed, the product needs to be separated and purified. Commonly used separation methods include extraction, distillation, column chromatography, etc. Extraction can be separated according to the difference in solubility between the product and the impurities in different solvents; distillation uses different boiling points to achieve separation; column chromatography separates the product from the impurities by the action of the stationary phase and the mobile phase to obtain a pure 4- (trifluoromethyl) -3 -quinoline carboxylic acid.
    Synthesis of this compound requires fine operation in each step, and strict control of the reaction conditions and parameters in order to obtain a product with satisfactory yield and purity, meeting the quality requirements of various fields.
    3 - Quinolinecarboxylic acid, 4- (trifluoromethyl) - in which areas
    4- (trifluoromethyl) -3 -quinoline carboxylic acid, this compound has extraordinary uses in many fields such as medicine and material science.
    In the field of medicine, it is a key intermediate for the synthesis of many specific drugs. Due to its unique chemical structure, it can be combined with other active groups through specific chemical reactions to create antibacterial drugs. Taking quinoline antibacterial drugs as an example, by using this compound as a starting material and going through multiple steps, antibacterial drugs with significant inhibitory activity against a variety of bacteria can be constructed. Its mechanism of action may be related to interfering with bacterial DNA replication and transcription, which can effectively kill or inhibit bacterial growth and provide a powerful weapon for the treatment of bacterial infections.
    In the field of materials science, 4- (trifluoromethyl) -3-quinoline carboxylic acid also has important applications. Because it contains trifluoromethyl, it is endowed with special physical and chemical properties, such as good thermal stability, chemical stability and low surface energy. It can be used to prepare special polymer materials and introduce them into the main chain or side chain of the polymer to improve the weather resistance and corrosion resistance of the material. For example, it is used to make high-performance composites in the aerospace field, so that the material can still maintain stable performance in extreme environments, ensuring the safe and reliable operation of aircraft.
    In addition, in the field of organic synthetic chemistry, it is often used as a key building block. With its quinoline ring and trifluoromethyl activity, it can participate in various organic reactions, such as nucleophilic substitution, electrophilic substitution, metal catalytic coupling reaction, etc. Organic synthesis chemists can use this to construct complex organic molecular structures, lay the foundation for the development of new functional materials and bioactive molecules, promote the continuous development of organic synthesis chemistry, and open up more unknown chemical space.
    3 - Quinolinecarboxylic acid, 4- (trifluoromethyl) - What is the market outlook?
    4- (trifluoromethyl) -3-quinolinecarboxylic acid, this substance has a promising market prospect in the present, or not? Let me tell you in detail for you.
    Looking at the current development of chemical and pharmaceutical fields, many emerging technologies and research directions continue to emerge. 4- (trifluoromethyl) -3-quinolinecarboxylic acid, as a class of organic synthesis intermediates, has emerged in the field of medicinal chemistry. Due to the special structure of trifluoromethyl, compounds are endowed with unique physical, chemical and biological activities. In the process of many new drug development, such structures are often used to improve drug fat solubility, metabolic stability and target binding ability.
    In recent years, the popularity of pharmaceutical research and development has continued to rise, and the demand for characteristic intermediates has also risen. 4- (trifluoromethyl) -3-quinoline carboxylic acid, as a key raw material for potential drug synthesis, is expected to usher in more market opportunities. Some innovative pharmaceutical companies are actively exploring novel chemical structures for drug creation, and such characteristic quinoline carboxylic acid derivatives may become the focus of their attention.
    However, although the market prospect is promising, there are also challenges. First, the optimization of the synthesis process is crucial. If we can develop more efficient and green synthesis routes and reduce production costs, we can gain an advantage in the market competition. Second, peer competition is fierce. As its potential value is recognized by more people, or more companies are involved in related production and R & D, how to stand out requires companies to have strong technical strength and innovation capabilities.
    Overall, 4- (trifluoromethyl) -3-quinoline carboxylic acid is in the market prospect, with both opportunities and challenges. For companies with technological and innovative advantages, they may be able to take advantage of this to open up a vast world in the market.