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3 - quinolinecarboxylic acid, 2 - (ethylthio) -6,7 - difluoro - 4 - hydroxy -, what are the chemical properties of ethyl ester
2 + - (ethylthio) -6,7-difluoro-4-hydroxy-3-quinoline carboxylic acid ethyl ester, this is an organic compound. Its chemical properties are unique and contain many interesting things.
First of all, its physical properties are often crystalline, and the color and white matter are pure. It is quite stable under conventional conditions. When it encounters a hot topic or an open flame, it is easy to change. Its melting point is specific, just like its unique coordinate on the temperature axis, which is an important symbol for identifying this substance.
In addition to solubility, it seems that people have their own preferences. This substance can be freely dispersed in some organic solvents, such as ethanol and acetone, which are like fish getting water, but it is difficult to be compatible in water, such as the gap between oil and water.
When it comes to chemical activity, the groups in its molecules are like members who perform their duties, cooperating with each other and restricting each other. Ethyl sulfide groups are like flexible strategists, giving molecules unique reactivity and can participate in many reactions such as nucleophilic substitution, just like dancing on the chemical reaction stage. Fluorine atoms are like strong guardians, enhancing molecular stability and changing the distribution of electron clouds, affecting the reaction process. Hydroxyl groups are like gentle craftsmen, which can participate in both esterification and oxidation reactions, showing a variety of chemical behaviors.
In chemical reactions, it is like a highly skilled dancer. Under different conditions, it can change dance steps and undergo various reactions. When meeting suitable reagents, ester-based hydrolysis can be carried out, such as unlocking the rope of bondage and releasing new chemical vitality. When encountering nucleophiles, it is like a friendly party, where nucleophilic substitution occurs and new compounds are generated. In the field of organic synthesis, this compound is like a key to unlocking treasures. It can be used as a key intermediate to help synthesize more complex and unique organic molecules, adding color to the magnificent picture of chemistry.
3 - quinolinecarboxylic acid, 2 - (ethylthio) -6,7 - difluoro - 4 - hydroxy -, ethyl ester What are the uses
Ethyl 2 + - (ethylthio) -6,7 -difluoro-4-hydroxy-3-quinoline carboxylate is an important organic compound with significant uses in many fields.
In the field of medicine, it is often the key intermediate for synthesizing antibacterial drugs. The special structure of this compound gives it unique antibacterial activity. With its chemical structure characteristics, it can effectively inhibit the growth and reproduction of bacteria, and then be used to fight against infections caused by various bacteria. For example, it can play a good therapeutic effect on bacterial infections in the respiratory tract, urinary tract and other parts.
In the field of pesticides, 2 + - (ethylthio) -6,7-difluoro-4-hydroxy-3-quinoline carboxylate ethyl ester also plays an important role. It can be used as a raw material for the synthesis of high-efficiency pesticides to resist crop pests and pathogens. By precisely acting on the specific physiological processes of pests and pathogens, it can protect crops and help improve crop yield and quality.
In the field of organic synthetic chemistry, as a key intermediate, it can participate in the synthesis of a variety of complex organic compounds. Chemists can introduce different functional groups based on the structure of this compound and use various chemical reactions to construct more complex and diverse organic molecular structures, providing a rich structural basis for new materials, drug development, etc.
In summary, 2 + - (ethylthio) -6,7-difluoro-4-hydroxy-3-quinoline carboxylate ethyl ester plays an indispensable role in the fields of medicine, pesticides and organic synthesis, and is of great significance to promote the development of related fields.
What is the synthesis method of 3 - quinolinecarboxylic acid, 2 - (ethylthio) -6,7 - difluoro - 4 - hydroxy -, ethyl ester
The synthesis of 2 + - (ethylthio) -6,7 -difluoro-4-hydroxy-3-quinoline carboxylic acid ethyl ester is a key content in organic synthesis. The synthesis method of this compound can be obtained according to the traditional process wisdom contained in "Tiangong Kaiwu" and combined with modern chemical knowledge and technology.
First, it is necessary to choose a suitable starting material. Usually a compound containing quinoline structure is used as a base, supplemented by reagents containing ethylthio, fluorine atoms, hydroxyl groups and ethyl ester groups. If a specific quinoline derivative is used as the starting point, the characteristics of its structure determine the direction and difficulty of the reaction. This starting material needs to undergo a multi-step reaction to gradually introduce the required functional groups. < Br >
First look at the introduction of fluorine atoms. The method of nucleophilic substitution can be used. Under suitable reaction conditions, fluorine-containing reagents, such as potassium fluoride, are introduced into the specific position of the quinoline structure. During the reaction, it is necessary to control the temperature and time, and choose an appropriate solvent to assist the reaction. Commonly used solvents such as dimethylformamide (DMF), whose polarity can promote the smooth occurrence of ionic reactions.
The second time is the introduction of ethylthio. Sulfur-containing reagents, such as sodium ethanethiol, can react with appropriately activated quinoline intermediates. This reaction also requires strict regulation of conditions, such as reaction temperature and pH. The amount of alkali needs to be accurate. Too much or too little will affect the yield and selectivity of the reaction.
Furthermore, the introduction of hydroxyl groups. Or by hydrolysis reaction, some functional groups that are easy to hydrolyze can be converted into hydroxyl groups. This process requires a high pH of the reaction environment. Peracid or perbase may cause side reactions to occur, affecting the purity of the target product.
As for the formation of ethyl ester groups, the common method is to esterify ethanol and corresponding carboxylic acids in the presence of a catalyst. Concentrated sulfuric acid is often used as a catalyst for this reaction, but attention should be paid to its corrosiveness and control of reaction conditions to prevent side reactions such as carbonation.
The whole synthesis process requires multiple steps of reaction, each step needs to be carefully operated and monitored. After each step of reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to remove impurities and obtain a high-purity target product 2 + - (ethylthio) -6,7 -difluoro-4-hydroxy-3-quinoline carboxylic acid ethyl ester. In this way, a satisfactory synthesis effect can be obtained.
3 - quinolinecarboxylic acid, 2 - (ethylthio) -6,7 - difluoro - 4 - hydroxy -, ethyl ester What is the price in the market
2 + - (ethylthio) -6,7-difluoro-4-hydroxy-3-quinoline carboxylic acid ethyl ester, the price of this compound in the market is difficult to determine. The price of this compound often changes due to various reasons, such as the purity of the quality, the amount of quantity, the situation of supply, and even the difficulty of making it.
In the past, if you wanted this for chemical products, or because of the difficulties in the production method, its production was limited, and the price was not cheap. However, the times change, if the current technology advances, the production will gradually increase, and the price may drop.
And its price varies in different places. Prosperous cities and remote cities have different supply and demand, and prices are different. Furthermore, if the buyer needs a large amount, the business may offer a good price in order to promote sales; if only a little, the price may be slightly higher.
To know the price, it is advisable to visit the market of chemical raw materials and consult the vendors; or explore the e-commerce platform of chemical materials to get a more accurate price.
3 - quinolinecarboxylic acid, 2 - (ethylthio) -6,7 - difluoro - 4 - hydroxy -, ethyl ester what is the safety and toxicity
2 + - (ethylthio) -6,7 -difluoro-4-hydroxy-3-quinoline carboxylate ethyl ester, this substance is related to safety and toxicity, and is hereby described in detail in ancient Ya's words.
This substance may be used in the chemical and pharmaceutical fields, but its safety cannot be ignored. When it comes to toxicity, if ingested in excess, it may cause damage to the viscera. In the human body, it may affect the digestive system, causing nausea and vomiting; or it may involve the nervous system, causing dizziness and fatigue. If it comes into contact with the skin, or causes allergies, it will look red, swollen and itchy.
And this substance should not be underestimated in the environment. If it flows into the water source, it may endanger aquatic organisms and cause ecological imbalance. If it is scattered in the soil, or affects the growth of vegetation, it will damage the water and soil.
Therefore, when using and disposing of this material, care must be taken. Practitioners need to wear protective gear, such as protective clothing, gloves, masks, etc., to prevent contact and inhalation. When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants to avoid accidents. When discarding, it should also be handled properly in accordance with regulations, so as not to pollute the environment and harm life. In this way, it can achieve a safe and safe coexistence with nature.