3 Quinolinecarbonitrile
quinoline thiophene imidazole thiazole

3-quinolinecarbonitrile

Taiy Chemical

    Specifications

    HS Code

    560729

    Chemical Formula C10H6N2
    Molar Mass 154.17 g/mol
    Appearance Solid
    Melting Point 198 - 202 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading 3-quinolinecarbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    3 - What are the main uses of quinolinecarbonitrile?
    3 + -Quinoline formonitrile (3+-quinolinecarbonitrile) is useful in various fields.
    In the field of medicinal chemistry, it is a key intermediate for the synthesis of many specific drugs. Because the structure of quinoline has unique physiological activity, based on this, methonitrile groups can significantly change the properties of compounds. Doctors can use it to create antibacterial and anti-cancer drugs. For example, when developing anti-cancer drugs, 3 + -quinoline formonitrile structure can precisely target specific targets of cancer cells, interfere with the metabolism and proliferation of cancer cells, thereby inhibiting the development of cancer and bringing vitality to patients.
    In the field of materials science, 3 + -quinoline formonitrile also has extraordinary performance. Due to its molecular structure properties, it can be used to prepare materials with special optical and electrical properties. Materials with excellent fluorescence properties can be prepared and applied to devices such as Light Emitting Diodes (LEDs). This material has high luminous efficiency and good stability, which can make LED lighting more energy-saving and long-lasting. It can also help the progress of display technology and make the screen display color more gorgeous and clear.
    In the field of organic synthesis chemistry, 3 + -quinoline formonitrile is an important building block for the construction of complex organic molecules. Chemists can use its active reaction check point to construct organic compounds with exquisite structures and unique functions through various organic reactions, such as nucleophilic substitution and addition. This not only enriches the variety of organic compounds, but also lays the foundation for the subsequent development of new materials and drugs, promoting the continuous progress of organic synthetic chemistry and expanding the boundaries of human understanding and control of the organic world.
    3 - What are the physical properties of quinolinecarbonitrile
    3 + -Quinoline formonitrile is a kind of organic compound. Its physical properties are quite unique, let me tell you one by one.
    When it comes to appearance, it usually appears as a solid state. However, its specific appearance and color may vary depending on the purity and preparation method. It is usually a white to light yellow crystalline powder. This is its intuitive appearance, which is easy for the reader to initially identify.
    As for the melting point, it is also an important physical property. After many experiments, its melting point is roughly within a specific temperature range. This temperature range plays a key guiding role in various chemical operations and practical applications. Due to its melting point, it is related to the setting of heating, melting and other operating conditions, which has a profound impact on subsequent chemical reactions and material processing.
    In terms of solubility, 3 + -quinoline formonitrile exhibits specific solubility in common organic solvents. In some organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), it has a certain solubility. This solubility provides convenient conditions for its application in the field of organic synthesis. During the synthesis process, it can be dissolved and dispersed with the help of suitable solvents, so that it can better participate in the chemical reaction and promote the smooth progress of the reaction.
    In water, its solubility is relatively limited. This property requires careful consideration of its existence and behavior in systems involving aqueous phases. Because it is insoluble in water, it may exist in the form of solid particles in aqueous environments, which poses special requirements for the design of related reactions and applications.
    In addition, although the physical properties of its density and boiling point are relatively unreported, they are also indispensable for a comprehensive understanding of this compound. The value of density affects its distribution in the mixed system; the boiling point is closely related to operations such as distillation and separation. Although the specific value may vary due to differences in research conditions, it is of important reference value for in-depth understanding of its physical behavior. In summary, the physical properties of 3 + -quinolinoformonitrile exhibit unique characteristics in terms of appearance, melting point, solubility, etc., which lay an important foundation for its application in chemical research and related fields.
    3 - What are the chemical properties of quinolinecarbonitrile
    3 + -Quinoline formonitrile, this is also an organic compound. Its molecule contains a quinoline ring and a cyano group, which has unique chemical properties.
    In terms of physical properties, 3 + -quinoline formonitrile is mostly solid at room temperature, with a certain melting point and boiling point. However, the exact value varies according to the purity and test conditions. Its solubility in water is quite low, because it is an organic compound, its polarity is weak, and its interaction with water is small. However, it has good solubility in common organic solvents, such as ethanol, dichloromethane, and chloroform. Due to the principle of "similar miscibility", the force between organic solvents and 3 + -quinoline formonitrile molecules is conducive to dissolution.
    In terms of chemical properties, cyanyl is its active reaction check point. The cyanyl group can be hydrolyzed and converted into a carboxyl group or an amide group under the catalysis of an acid or a base. If in acidic conditions, after hydrolysis, the cyanyl group is gradually converted into a carboxyl group to obtain 3 + -quinoline carboxylic acid. When alkali catalyzed hydrolysis, Mr. 3 + -quinoline formamide is formed, and 3 + -quinoline carboxylic acid is obtained by continuing the reaction.
    Cyanyl can also participate in nucleophilic addition reactions. Because its carbon atoms are partially positively charged, they are vulnerable to nucleophilic attack. If nucleophilic addition occurs with alcohols under alkali catalysis, an imide ether intermediate is formed, and a derivative of 3 + -quinoline formonitrile can be obtained by further reaction.
    The quinoline ring also gives 3 + -quin The quinoline ring is aromatic and relatively stable. However, the electron cloud densities at different positions on the ring are different, which makes it possible to undergo electrophilic substitution reactions. Usually, the electron cloud densities of the 5 and 8 positions of the quinoline ring are higher, and electrophilic reagents are easy to attack these two positions. If halogenation, nitrification, sulfonation and other electrophilic substitution reactions occur, the corresponding derivatives are formed.
    In addition, there is a π electron conjugation system in the 3 + -quinoline formonitrile molecule, which makes the compound have certain optical properties. Under appropriate conditions, it can absorb light of specific wavelengths and generate electron transitions, which has potential applications in the field of spectral analysis.
    3 - What are the synthetic methods of quinolinecarbonitrile
    There are many ways to synthesize 3-quinoline formonitrile. One of the common methods is to use quinoline as the starting material to react with cyanide reagents under suitable conditions. For example, quinoline can be reacted with cyanide agents such as potassium cyanide or sodium cyanide in the presence of suitable solvents and catalysts. In this process, the cyanyl group will replace the group at a specific position of quinoline to obtain 3-quinoline formonitrile.
    There are also compounds containing quinoline structure precursors. If the precursor molecule has active groups that can be replaced by cyanide groups at suitable positions, such as halogen atoms, sulfonate groups, etc., the target product can be prepared by nucleophilic substitution reaction with the cyanide reagent. For example, if the precursor is 3-haloquinoline, with the help of a catalyst such as a copper salt, the halogen atom is replaced by a cyanide group, resulting in the synthesis of 3-quinoline formonitrile.
    In addition, a quinoline ring can be constructed through a multi-step reaction and a cyanyl group can be introduced at the same time. First, a suitable aromatic compound and a nitrogen-containing compound are used to construct a quinoline parent nucleus through a series of reactions such as condensation and cyclization. In the cyclization step or subsequent reactions, a cyanyl group is ingeniously designed to be introduced. Although this approach is a little complicated, the reaction conditions and substrate structure can be flexibly adjusted, which also has a considerable impact on the purity and yield of the product. Each method has its advantages and disadvantages. In actual synthesis, the appropriate method should be carefully selected according to factors such as the availability of raw materials, cost, and difficulty of reaction conditions.
    3 - What is the price range of quinolinecarbonitrile in the market?
    I have not heard the exact price of 3 - + -quinoline nitrile in the market. However, the level of the price often varies depending on various factors. It may be related to the source of materials, the complexity and simplicity of the craftsmanship, the amount of market demand, or it may be related to the quality and quantity of trade.
    If the source of the material is easy to harvest and the supply is abundant, the price may be flat; on the contrary, if the material is scarce and hard to find, it will cause the price to be high. If the craftsmanship is complex, the labor is large, the time is long, and the technique is excellent, the price will rise; if the craftsmanship is simple, the cost is saved and the labor is easy, and the price will drop.
    The city's need is also the main reason. When there is a lot of demand, the merchants compete to supply it, and the price may rise; when there is a shortage of goods, it is difficult to sell, and the merchants want to promote trade, or reduce the price to lure customers. Quality is related to the top and bottom of the price. Everyone wants the best, and there is a market for the high price. No one cares about the inferior, and the lower price may be available for sale.
    As for the trade volume, when the batch is large, the merchants often give discounts in order to profit from the quick sale, and the price is low; if the quantity is small, the price may be relatively high due to the uneven distribution of freight, management, etc.
    According to common sense, the price of 3 - + -quinoline formonitrile, or due to the above ends, fluctuates greatly at different times. If you want to know the exact price, you should consult the chemical raw material suppliers, market trading platforms, or industry insiders to obtain an approximation of the actual price.