3-Isoquinolinecarboxylic acid, decahydro-6-(2-(1H-tetrazol-5-yl)ethyl)-, (3S,4aR,6R,8aR)-

This is a chemical substance named (3S, 4aR, 6R, 8aR) -decahydro-6- (2- (1H-tetrazol-5-yl) ethyl) -3-isoquinoline carboxylic acid. To know its chemical structure, let me tell you in detail.
The core of this compound is an isoquinoline ring, which is added with a carboxyl group at the 3rd position. This carboxyl group is active and can participate in many chemical reactions, such as ester formation and salt formation. The isoquinoline ring was modified by decahydro, indicating that it has a high degree of hydrogenation, and multiple carbon-carbon double bonds are hydrosaturated. This structure can enhance the stability and fat solubility of the compound. < Br >
A substituent containing 2- (1H-tetrazole-5-yl) ethyl is introduced at position 6. Among this substituent, the tetrazole ring has a unique electronic structure and reactivity, and is often used in pharmaceutical chemistry to improve the hydrophilicity, biological activity and metabolic stability of compounds. Ethyl, as a linking group, can adjust the molecular spatial structure and flexibility, and affect the interaction between compounds and targets.
The compound exists due to a specific stereochemical configuration (3S, 4aR, 6R, 8aR), and the spatial arrangement of isomers of different configurations is different, and the binding mode to biological targets may be different, which has a great impact on biological activity and pharmacokinetic properties.
This (3S, 4aR, 6R, 8aR) -decahydro-6- (2- (1H-tetrazol-5-yl) ethyl) -3-isoquinoline carboxylic acid has a unique chemical structure and the interaction of various parts, endowing it with specific physicochemical and biological activity properties. It may have important uses in organic synthesis, drug development and other fields.

3-Isoquinoline carboxylic acid, decahydro-6- (2- (1H-tetrazol- 5-yl) ethyl) -, (3S, 4aR, 6R, 8aR) - This substance has a variety of physical properties. Its appearance or specific form, however, no detailed color and crystal form are described. In terms of solubility, or due to the comprehensive action of polar groups and non-polar parts in the molecular structure, in some polar solvents such as water and alcohols, there may be a certain solubility, because tetrazolyl and carboxyl groups are hydrophilic; in non-polar solvents such as alkanes, the solubility may be poor. The melting point of
is crucial for the identification of its purity and material characteristics, but its specific value is not detailed. The same is true for the boiling point. Although it is not clear, it can be inferred that the intermolecular forces are enhanced due to the interaction of hydrogen bonds and van der Waals forces in the molecules, and the boiling point may be within a certain range. In terms of density, it is inferred from its molecular composition and structural compactness, or there is a specific value, and it is affected by the relative mass and spatial arrangement of molecules, or it is comparable to the density of common organic compounds.
Its refractive index can reflect the influence of the substance on the direction of light propagation, and is related to the symmetry of the electron cloud distribution and structure of the molecule. However, the specific value is lacking. In addition, the stability of the substance may vary depending on the chemical bond energy and group interaction within the molecule. Under certain conditions, it may remain stable, but under extreme conditions such as high temperature, strong acid and alkali, the molecular structure may change.

This is an organic compound, called (3S, 4aR, 6R, 8aR) -decahydro-6- (2- (1H-tetrazole-5-yl) ethyl) -3-isoquinoline carboxylic acid. In the field of chemistry, common uses are mainly in drug development. The structure of caine isoquinoline and tetrazole gives it unique biological activity.
isoquinoline compounds often have a variety of biological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. In this compound, the isoquinoline ring is the key structural basis, or affects its binding mode with biological targets. The decahydroisoquinoline part, due to its saturated cyclic structure, can change the molecular conformation and lipophilicity, affecting its absorption, distribution, metabolism and excretion in vivo.
Tetrazole group is very important in pharmaceutical chemistry. It is acidic and can participate in the formation of hydrogen bonds, enhancing the binding force between compounds and targets. At the same time, tetrazole can mimic carboxyl groups such as bioelectrons and other exposures, changing the physicochemical properties and biological activities of compounds. In this compound, 2- (1H-tetrazole-5-yl) ethyl side chains can specifically bind to biological targets, such as specific enzymes or receptors, and then exhibit therapeutic effects.
In the field of organic synthesis, this compound may be used as a key intermediate. Due to its complex polycyclic structure and functional groups, a series of structural analogs can be derived through various chemical reactions for drug screening and structural optimization, laying the foundation for the creation of new drugs.

To prepare 3-isoquinoline carboxylic acid, decahydro-6- (2- (1H-tetrazolyl-5-yl) ethyl) -, (3S, 4aR, 6R, 8aR) -, there are many methods.
First, or follow the classical path of organic synthesis. First take suitable starting materials and construct the basic skeleton with precise reaction steps. For example, select aromatics with specific substituents, and introduce key functional groups through nucleophilic substitution, addition and other reactions. This requires detailed regulation of reaction conditions, such as temperature, catalyst type and dosage. Changes in temperature can cause differences in reaction rate and selectivity; differences in catalysts can also affect the reaction process and yield.
times, modern synthesis technology can be borrowed. If the reaction catalyzed by transition metals is used, it has the advantages of high efficiency and high selectivity. Using specific transition metals as catalysts can guide the reaction to occur precisely at the target location and reduce side reactions. However, it is crucial to select suitable metal catalysts and ligands, and the reaction system needs to be strictly anhydrous and oxygen-free to maintain catalytic activity.
Furthermore, stereochemical control is also key to the synthesis of this compound. Because of its multiple chiral centers, chiral induction or chiral catalysts are required to obtain products of specific configurations. Chiral induction can use the inherent stereochemical information of the reactants to guide the stereochemistry of new bond formation; chiral catalysts can selectively promote the formation of products in a certain configuration.
In addition, the monitoring and optimization of the reaction process is indispensable. With thin-layer chromatography, nuclear magnetic resonance and other analytical methods, real-time insight into the reaction process can be used to fine-tune the reaction conditions according to the results to achieve the best synthesis effect.
Synthesis of 3-isoquinoline carboxylic acid, decahydro-6- (2- (1H-tetrazole-5-yl) ethyl) -, (3S, 4aR, 6R, 8aR) - requires comprehensive consideration of starting materials, reaction path, stereochemical control and reaction monitoring, and careful operation to obtain the ideal product.

3-Isoquinoline carboxylic acid, decahydro-6- (2- (1H-tetrazole-5-yl) ethyl) -, (3S, 4aR, 6R, 8aR) - This compound does have many potential applications in the field of medicine.
In the field of Guanfu medicine, this compound may have great value in the treatment of diseases. First, its unique structure may be used as a key starting material for the development of new drugs. Due to its specific spatial configuration and functional group combination, it can interact with specific targets in the body. For example, at some disease-related proteins or receptors, they are precisely bound by intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., and then regulate biological signaling pathways.
Second, it may emerge in the development of anti-tumor drugs. The formation and development of tumors involve many abnormal signaling and cell proliferation processes. This compound may inhibit the growth and spread of tumor cells by blocking specific carcinogenic signaling pathways. And because of its unique chemical structure, it is expected to avoid many drawbacks of traditional anti-tumor drugs, such as excessive toxic and side effects.
Third, it may also be used in the treatment of neurological diseases. Nervous system diseases often result from neurotransmitter imbalance and nerve cell damage. This compound may regulate the release and uptake of neurotransmitters, promote the repair and regeneration of nerve cells, and open up new avenues for the treatment of neurological diseases such as epilepsy and Parkinson's disease.
Fourth, in the field of cardiovascular diseases, it may act on related targets such as the angiotensin system to regulate blood pressure, improve heart function, and help prevent and treat cardiovascular diseases. In conclusion, 3-isoquinoline carboxylic acid, decahydro-6- (2- (1H-tetrazole-5-yl) ethyl) -, (3S, 4aR, 6R, 8aR) - have broad application prospects in the field of medicine, and bring new hope and opportunities for the treatment of many diseases.