3 Cyano 4 Chloro 7 Methoxyquinoline
quinoline thiophene imidazole thiazole

3-cyano-4-chloro-7-methoxyquinoline

Taiy Chemical

    Specifications

    HS Code

    932628

    Chemical Formula C11H8ClN3O
    Molecular Weight 233.654 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Melting Point Data may vary, check specific sources
    Boiling Point Data may vary, check specific sources
    Solubility In Water Low solubility
    Solubility In Organic Solvents May be soluble in some organic solvents like dichloromethane, etc.
    Density Data may vary, check specific sources
    Color Typically colorless to pale yellow solid

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    General Information
    Where to Buy 3-cyano-4-chloro-7-methoxyquinoline in China?
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    Frequently Asked Questions

    As a leading 3-cyano-4-chloro-7-methoxyquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3-cyano-4-chloro-7-methoxyquinoline?
    3-Hydroxy-4-methoxy-7-acetoxycoumarin, also known as the patriarch hemp, although this thing is not directly recorded in "Tiangong Kaiwu", but from the perspective of traditional herbal science and ancient formulas, its function can be deduced.
    In traditional Chinese medicine pharmacology, it has the effect of removing wind and dehumidification, promoting blood circulation and relieving pain. Rheumatism and arthralgia, pain in limbs and joints, unfavorable flexion and extension, this medicine can remove wind cold and dampness, clear meridians and collaterals, and relieve pain when blood vessels are unobstructed. The disease of bruising injuries, stagnation of qi and blood, local swelling and pain, it can promote blood circulation and remove blood stasis, dissipate blood stasis, reconcile qi and blood in the wound, and eliminate swelling and pain.
    In ancient recipes, coumarin compounds were often associated with health preservation and warding off evil spirits. Although there is no exact literature indicating that 3-hydroxy-4-methoxy-7-acetoxycoumarin is included in this list, its aroma is unique, or it plays a role in calming the mind, removing filth and preventing the epidemic in the usage of incense, medicinal pillows, etc. The ancients attached great importance to the harmony between the environment and the qi of the human body. Such aromas may create a fresh and upright atmosphere, which is beneficial to the body and mind.
    Although it is not contained in "Tiangong Kaiwu", combined with traditional medicine and prescription concepts, it can be seen that 3-hydroxy-4-methoxy-7-acetoxycoumarin may have important uses in removing wind and dehumidification, promoting blood circulation and relieving pain, and creating a beneficial environment. It has a certain position in the field of traditional health care.
    What are the synthesis methods of 3-cyano-4-chloro-7-methoxyquinoline?
    There are several methods for the synthesis of 3-benzyl-4-bromo-7-methoxybenzaldehyde. One method is to start with 3-benzyl-4-hydroxybenzaldehyde, through a bromination reaction, introduce a bromine atom at a designated location, and then perform a methoxylation reaction with an appropriate methylation reagent to obtain the target product. At the time of bromination, liquid bromine or N-bromosuccinimide (NBS) can be selected as the bromine source and carried out under suitable solvents and reaction conditions. Methylation reactions are often completed with dimethyl sulfate or iodomethane as reagents and catalyzed by bases. < Br >
    Another method can be used to prepare aromatic compounds containing methoxy groups first, and then introduce benzyl and bromine atoms. For example, using 4-methoxybenzaldehyde as raw material, benzyl is first introduced into its aromatic ring through benzylation reaction, and then bromination is carried out to achieve the purpose of synthesizing 3-benzyl-4-bromo-7-methoxybenzaldehyde. The benzylation reaction can be carried out by benzyl halide and base in a suitable solvent. The bromination step is also carried out according to the conventional bromination method, and the reaction parameters are adjusted according to the specific reaction conditions and substrate activity.
    Furthermore, the target molecular structure can be gradually constructed from the corresponding phenolic compounds through a series of reactions such as methoxylation, benzylation, bromination, etc. Each step of the reaction requires fine control of reaction conditions, such as temperature, reactant ratio, reaction time, etc., to ensure the selectivity and yield of the reaction. Such various methods have their own advantages and disadvantages. In actual synthesis, the choice should be weighed according to factors such as the availability of raw materials, the difficulty of reaction operation, and cost.
    What are the physical properties of 3-cyano-4-chloro-7-methoxyquinoline?
    3-Hydroxy-4-methoxy-7-acetoxycoumarin, this is a delicate organic compound. Its physical properties are quite unique.
    Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and use, and also shows convenient characteristics in many chemical reactions and preparation.
    When it comes to the melting point, it is usually in a specific temperature range, about [X] ° C. The stability of the melting point provides a key basis for identifying the substance and controlling its purity. When it is heated to the melting point, the substance gradually converts from a solid state to a liquid state. This process is orderly and follows specific physical laws.
    In terms of solubility, the substance exhibits a certain solubility in organic solvents, such as ethanol, acetone, etc. The moderate solubility makes it easier to integrate it into a specific system in the fields of preparing solutions, performing reaction operations, and developing pharmaceutical formulations. However, the solubility in water is relatively limited, which also determines its behavior in different media environments.
    Its density also has a specific value, about [X] g/cm ³. This density value reflects the mass per unit volume of a substance, which is of great significance for accurately controlling its dosage and ratio in practical application scenarios such as chemical production and material preparation.
    In addition, the substance may have certain optical properties. Or under specific wavelengths of light, it presents a unique absorption spectrum or fluorescence emission phenomenon. This optical property holds potential application value in cutting-edge scientific research fields such as analysis and detection, fluorescent labeling, etc.
    In summary, the physical properties of 3-hydroxy-4-methoxy-7-acetoxycoumarin are rich and unique, laying a solid foundation for its in-depth research and wide application in many fields such as chemistry, medicine, materials, etc.
    What are the chemical properties of 3-cyano-4-chloro-7-methoxyquinoline?
    3-Hydroxy-4-methoxy-7-acetoxycoumarin, this is a class of coumarin compounds with unique chemical properties. Under the paradigm of the ancient book "Tiangong Kaiwu", the ancient saying is as follows:
    This compound has a lactone structure and is in a cyclic state, similar to the jade ring formed in heaven, containing unique chemical activity. Its lactone ring is active and can be opened in case of alkali, just like the jade ring is cracked by strong external force to form cis-hydroxycinnamate, but this salt is unstable. If it is heated or acidified, it is cyclic and changes back to the lactone structure, just like the jade ring recast. This is its significant chemical property. < Br >
    And its molecules contain phenolic hydroxyl groups, which are common to phenolic compounds. When encountering ferric chloride test solution, it can show a special color, or appear purple or blue, just like a unique pattern painted on plain silk, so that its existence can be identified.
    Furthermore, the introduction of methoxy groups makes the electron cloud distribution of the molecule different, affecting its physical and chemical properties. Methoxy groups have a electron supply effect, which can increase the density of the electron cloud of the benzene ring, making it more prone to electrophilic substitution reactions, just like adding troops to the city, making it easier for the city to launch counterattacks against foreign enemies. < Br >
    The acetoxy group is also an important group. Under appropriate conditions, a hydrolysis reaction can occur to remove the acetyl group and generate a hydroxyl group. This process is similar to the metamorphosis of a cicada, and the change of the group leads to the change of the properties of the compound.
    Because of the interaction of various groups in its structure, this compound has its own characteristics of solubility in organic solvents. It can be better dissolved in some polar organic solvents, such as ethanol and acetone. It is like a fish getting water, but its solubility in water is relatively low, just like a boat traveling in shallow water, making it difficult to move smoothly. These chemical properties are of great significance in many fields, or used in drug development or chemical synthesis, and can be skillfully used according to their characteristics.
    What is the market price of 3-cyano-4-chloro-7-methoxyquinoline?
    In today's world, the price of goods in the market is varied and subject to various factors. However, if you want to ask the market price of 3-hydroxy-4-chloro-7-methoxybenzaldehyde, it is difficult to respond to it with certainty.
    The price of such goods in the market is primarily related to the situation of supply and demand. If there are many people in the world who want it, and it is widely used, but the products are rare, the price will be high; if there are few people who want it, and there are many products, and the goods are in the market, the price will decline.
    Furthermore, the difficulty of its preparation is also a major factor. If the production of this product requires delicate techniques, rare materials, or difficult processes, labor-intensive and time-consuming, its price will be high; if the preparation method is simple, and the required things are easily available, the price may be slightly lower.
    In addition, the competition in the market can also make its price different. There are many competitors in the industry, competing for profit, competing for a share of the market, or lowering their prices to attract; if there are few competitors in this industry, the price may be maintained at a high level.
    And things change, and luck is impermanent. The weather changes, disasters are suddenly approaching, or the production of raw materials is damaged, affecting the manufacture of this product, and the price also changes accordingly; the issuance of decrees, the strict regulation, or the cost of production may increase or decrease, causing its price to fluctuate.
    Overall, in order to know the current price of 3-hydroxy-4-chloro-7-methoxybenzaldehyde in the market, it is necessary to consider all the reasons in detail, or to consult Jia people and brokers in the city in person, you can get a closer number, and it is difficult to judge its price based on the truth.