3 Aminoisoquinoline
Quinoline Thiophene Imidazole Thiazole
3-Aminoisoquinoline
Chemical Formula C9H8N2
Molecular Weight 144.17 g/mol
Appearance Solid
Melting Point 129 - 133 °C
Boiling Point 342.4 °C at 760 mmHg
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, chloroform
Pka ~4.79
Density 1.214 g/cm³
Odor Odorless (usually)
Stability Stable under normal conditions
FAQ

What are the main uses of 3-aminoisoquinoline?

The light of 3-hydroxyisobutyric acid, its main use, is covered in "Tiangong Kaiwu", which is related to many fields of chemical industry and medicine.

In the field of chemical industry, 3-hydroxyisobutyric acid is often the key raw material for organic synthesis. For example, it is used to prepare specific esters, which are widely used in flavors, coatings and other industries. Taking the preparation of a certain perfume ester as an example, through a specific chemical reaction, 3-hydroxyisobutyric acid is combined with the corresponding alcohols. Under suitable catalytic conditions, ester fragrances with unique aromas can be generated, adding color to the perfume industry.

In the field of medicine, its importance should not be underestimated. 3-hydroxyisobutyric acid can be used as an intermediate in the synthesis of many drugs. For some drugs with special curative effects, 3-hydroxyisobutyric acid is an indispensable link in the synthesis path. For example, a certain type of drug used to regulate human metabolism, in its complex synthesis steps, 3-hydroxyisobutyric acid is transformed through a series of fine reactions to gradually build the active ingredients of the drug, help the drug to exert the effect of regulating the balance of human metabolism, and then have a significant effect on the treatment and prevention of related diseases.

In summary, the light of 3-hydroxyisobutyric acid is of great value in the chemical industry, medicine, etc. It is like a pearl hidden in the treasure house of industry and medicine. After clever use, it blooms brilliantly, benefiting many industries and people's lives.

What are the physical properties of 3-aminoisoquinoline?

3-Hydroxyisobutyric acid is an organic compound with a wide range of uses in the chemical and pharmaceutical fields. Its physical properties are as follows:

###Properties
Under normal conditions, 3-Hydroxyisobutyric acid is a white crystalline solid with a fine texture, as pure as the first snow in winter, and feels dry to the touch. Its crystal structure is regular. Under the light, it occasionally shines with a faint luster, just like a tiny star hidden in it.

###Melting point and boiling point
The melting point is about 132-135 ° C. At this temperature, it is like ice in the warm sun, gradually melting from a solid state to a liquid state, realizing the transformation of form. The boiling point is about 212 ° C. When the temperature rises to this point, the molecular movement becomes more and more intense, breaking free from the shackles of the liquid phase and rising into a gaseous state.

###Solubility
This substance is easily soluble in water, just like a fish entering water, it can closely embrace water molecules to form a uniform and stable solution. In organic solvents such as ethanol and ether, it also has a certain solubility, showing affinity for different solvents, just like a socialite who is good at getting along with all kinds of friends.

###Smell and taste
3-hydroxyisobutyric acid has a weak and special smell, not pungent, but has an indescribable light fragrance, which needs to be close to a fine smell to detect. As for the taste, although there is no exact literature description, it is speculated that it should be similar to similar organic acids, or have a slightly sour taste.

###density
Its density is relatively stable, about 1.185g/cm ³ under specific conditions, indicating that in a unit volume, it contains a certain amount of mass, giving it a unique "weight" in various systems, just like having a unique "weight" label in the material world.

What are the chemical synthesis methods of 3-aminoisoquinoline?

3-Hydroxyisobutyric acid, the chemical synthesis method of this substance, has been explored by many parties throughout the ages, and now Chen's number method is below.

First, isobutyraldehyde is used as the starting material. First, isobutyraldehyde and hydrogen peroxide are oxidized under the action of a specific catalyst. This reaction condition is quite critical, the temperature needs to be controlled in a moderate range, about [X] ℃, and the amount of catalyst is also exquisite, and precise preparation can be used to efficiently convert isobutyraldehyde into 3-hydroxy isobutyric acid. The reaction mechanism is that the oxygen atom of hydrogen peroxide launches a nucleophilic attack on the aldehyde-based carbon of isobutyraldehyde, and through a series of electron rearrangements and bonds, the target product is finally obtained. < Br >
Second, it can be synthesized from methacrylic acid through a specific reduction path. Select a suitable reducing agent, such as lithium aluminum hydride. However, lithium aluminum hydride has high activity and must be handled with caution when using it. In a low temperature and anhydrous environment, methacrylic acid is slowly dripped into the reaction system containing lithium aluminum hydride. The low temperature is usually maintained below [Y] ° C to prevent the reaction from being too violent. During this process, the carbon-carbon double bond of methacrylic acid and the carboxyl group will undergo a reduction reaction one after another. By skillfully controlling the reaction conditions and the amount of reducing agent, the carboxyl group can be partially reduced to a hydroxyl group to obtain 3-hydroxy isobutyric acid.

Third, 3-chloroisobutyric acid is used as the raw material. 3-Chloroisobutyric acid is co-heated with sodium hydroxide solution to undergo a substitution reaction. This reaction is carried out in aqueous solution, and the concentration of sodium hydroxide, reaction temperature and time are all factors that affect the yield of the reaction. The temperature should be maintained at about [Z] ° C. After a period of reaction, the chlorine atom is replaced by a hydroxyl group, and 3-hydroxyisobutyric acid is obtained.

All kinds of synthesis methods have advantages and disadvantages. With isobutyric aldehyde as the starting material, the raw material is relatively easy to obtain, but the reaction conditions are relatively harsh; the methacrylic acid reduction method, although it can obtain high-purity products, the reducing agent is expensive and dangerous to operate; the 3-chloroisobutyric acid substitution method is relatively simple to operate, but it is necessary to pay attention to the occurrence of side reactions. To achieve the best synthetic effect, it is necessary to consider the actual situation, such as raw material cost, equipment conditions, product purity requirements, etc.

What are the applications of 3-aminoisoquinoline in the field of medicine?

3-Hydroxyisobutyric acid light is widely used in the field of medicine.

Cover 3-Hydroxyisobutyric acid light, in the preparation of medicine, is often a key raw material. It has unique chemical properties and can help synthesize a variety of specific drugs. For example, when making blood lipid-lowering drugs, this substance can be a starting material. After many delicate chemical reactions, it is ingeniously combined with other compounds to obtain a molecular structure with the effect of regulating blood lipids. Doctors can rely on this drug to treat disorders of blood lipids, such as hypercholesterolemia, hypertriglyceridemia, etc., so that patients have normal blood lipids and reduce the risk of cardiovascular diseases.

In some anti-inflammatory and anti-swelling drugs, 3-hydroxyisobutyric acid light is also very useful. It can participate in the construction of active pharmaceutical ingredients, and by virtue of its chemical properties, regulate the pathway of human inflammatory response. When the body encounters inflammation, this drug can inhibit the release of inflammatory mediators, slow down redness, swelling, heat and pain, and help patients recover quickly. Inflammative diseases such as arthritis and dermatitis can be treated with drugs containing this ingredient.

Furthermore, in the development of drugs related to the nervous system, 3-hydroxyisobutyric acid light has also emerged. It may be involved in the regulation of neurotransmitters or the process of nerve cell protection. Studies have shown that it can help maintain the normal function of nerve cells, and may have potential value in the prevention and treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. Although it is still in the stage of in-depth research, it has seen its unique advantages, and may open up new paths for the treatment of neurological diseases in the future.

What is the market prospect of 3-Aminoisoquinoline?

In today's world, the bright market prospect of tri-hydroxyisobutyric acid is widely seen. This substance has a wide range of uses, and it has extraordinary properties in chemical and pharmaceutical fields.

In the field of chemical industry, tri-hydroxyisobutyric acid is an important raw material. Based on it, a variety of fine chemicals can be prepared. For example, some high-performance plastic additives can be added to plastics to increase their toughness and heat resistance, so that plastic products can maintain their good state under various harsh environments. And in the production of coatings, it can be used as a key ingredient to make coatings better adhesion, brighter color, and wear resistance and corrosion resistance. Therefore, in the upgrading of the chemical industry and the improvement of product quality, tri-hydroxyisobutyric acid plays a pivotal role. Chemical companies are increasingly demanding it, and the market scale is also expanding.

As for the field of medicine, tri-hydroxyisobutyric acid has also emerged. After research, it is an indispensable intermediate in the synthesis of several drugs. With its unique chemical structure, it can assist in the synthesis of a variety of drugs with special curative effects, such as targeted drugs for specific diseases. Such drugs precisely act on the patient's site, with significant curative effect and small side effects, and are favored by the pharmaceutical industry. With the advancement of pharmaceutical technology and the continuous deepening of the research and development of new drugs, the application prospects of tri-hydroxyisobutyric acid in the field of medicine are broader, and the demand for it by pharmaceutical companies is also on the rise.

Furthermore, with the rise of environmental awareness, the concept of green chemistry has gradually entered the hearts of the people. In the synthesis process of tri-hydroxyisobutyric acid, if it can adopt green environmental protection methods, it will be more in line with the needs of the times. Its environmental protection characteristics will attract more companies to invest in R & D and production, thereby promoting further market expansion.

From this perspective, tri-hydroxyisobutyric acid is on the market, just like the day it first rose, with a bright future. The needs of the chemical industry, medicine and other fields have paved the way for it, and the need for environmental protection has further strengthened it. In the future, it will surely shine in the market and attract attention from all parties.