2 Trifluoromethyl Quinoline 4 Carboxylic Acid
quinoline thiophene imidazole thiazole

2-(Trifluoromethyl)quinoline-4-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    190267

    Chemical Formula C11H6F3NO2
    Molar Mass 241.17 g/mol
    Appearance Solid (usually)
    Melting Point Specific value needed from literature
    Boiling Point Specific value needed from literature
    Solubility In Water Low (estimated as it's an organic acid with fluorinated group)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Acidity Pka Specific value needed from literature
    Color Colorless to off - white (typical for many organic acids)
    Odor Odorless or very faint odor (estimated for this type of compound)

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    General Information
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    Frequently Asked Questions

    As a leading 2-(Trifluoromethyl)quinoline-4-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2- (trifluoromethyl) quinoline-4-carboxylic acids?
    The chemical properties of (triethylphenyl) silicone oil-4-carboxyl group are the key content involved in the field of organic chemistry. In this compound, (triethylphenyl) silicone oil has a specific structure and properties, and the introduction of 4-carboxyl group significantly affects its chemical behavior.
    In terms of its chemical properties, one is acidic. The 4-carboxyl group can ionize hydrogen ions, which is weakly acidic and can neutralize with bases. In case of sodium hydroxide, it can form corresponding carboxylate and water. This reaction follows the basic principle of acid-base neutralization and is quite common in organic synthesis and chemical analysis.
    Second, it has the activity of esterification reaction. The 4-carboxyl group can be esterified with alcohols under acid catalysis to form ester compounds. In this process, the hydroxyl group of the carboxyl group and the hydroxyl group of the alcohol dehydrate a molecule of water to form an ester bond. This reaction is an important way to prepare various ester derivatives and is widely used in many fields such as fragrance and drug synthesis.
    Third, it can participate in nucleophilic substitution reactions. Carbonyl carbons of carboxylic groups have certain positive electricity and are vulnerable to attack by nucleophilic reagents. For example, when reacted with amines, amide compounds can be formed. This is an important method for synthesizing compounds containing amide bonds and is indispensable in the preparation of polymer materials and bioactive molecules.
    Fourth, the (triethylphenyl) silicone oil part also affects the overall chemical properties. Its special silicone structure endows the compound with certain characteristics such as heat resistance, weather resistance and low surface tension. Interacting with the chemical properties of 4-carboxyl groups makes the compound exhibit unique chemical behavior and application potential in specific environments and reaction systems.
    What are the synthesis methods of 2- (trifluoromethyl) quinoline-4-carboxylic acid?
    To prepare 2 - (triethyl) propane - 4 - carboxylic acid, the method is as follows:
    First, start with halogenated hydrocarbons. Take an appropriate halogenated hydrocarbon and make it react with metal magnesium to form a Grignard reagent. Then, make this Grignard reagent with the corresponding carbonyl compound, such as aldehyde or ketone, for addition reaction. The addition product is hydrolyzed to obtain alcohol. Then the alcohol is oxidized to gradually reach the carboxyl-containing compound, and the carbon chain is adjusted through appropriate steps to finally obtain 2 - (triethyl) propane - 4 - carboxylic acid. In this process, the choice of halogenated hydrocarbons depends on the desired carbon chain structure, and the reaction conditions of each step, such as temperature, solvent, etc., also need to be precisely controlled to ensure that the reaction is in the desired direction.
    Second, the carboxylic acid derivative is used as the base. For example, select a suitable ester. Through the ester condensation reaction, the carbon chain can be grown. Under the action of a base, two molecules of esters interact to form β-carbonyl esters. After that, a series of reactions such as decarboxylation of β-carbonyl esters are carried out. The decarboxylation reaction often requires a specific temperature and catalyst, through which the structure can be adjusted, the target carbon chain part can be gradually introduced, and the carboxyl group can be formed at the appropriate position. At the same time, the separation and purification of the product after the reaction is also critical. Distillation, recrystallization and other methods can be used to obtain pure 2- (triethyl) propane-4-carboxylic acid.
    Third, use olefins as raw materials. Take advantage of the addition reaction characteristics of olefins. If the olefin is first added to hydrogen halide to obtain halogenated hydrocarbons, the halogenated hydrocarbons can be made as described above to make Grignard reagents, and then the subsequent reaction can be carried out. Alternatively, the olefin is hydroformylated with carbon monoxide and hydrogen under the action of a catalyst, and an aldehyde group is introduced. The aldehyde group can be oxidized to obtain a carboxyl group, and then a triethyl methyl structure can be constructed by suitable reaction to eventually form the target product. In this approach, the choice of olefins depends on the target product carbon frame, and the efficiency of the catalyst has a significant impact on the reaction rate and selectivity.
    In which fields are 2- (trifluoromethyl) quinoline-4-carboxylic acids used?
    2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E5%96%B9%E5%95%89 and 4-%E7%BE%A7%E9%85%B8%E5%9C%A8%E5%85%B6%E4%BD%93%E4%BD%93%E4%B8%8E%E5%8C%96%E5%AD%A6%E5%8C%96%E5%AD%A6%E7%9B%B8%E5%85%B3%E9%A2%86%E5%9F%9F%E5%A4%9A%E6%9C%89%E5%BA%94%E7%94%A8.
    In the field of medicine, both have extraordinary uses. 2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E5%96%B9%E5%95%89 can be used as raw materials for pharmaceutical synthesis, and with its unique structure, it can become many drugs with specific curative effects, helping to cure diseases. 4-%E7%BE%A7%E9%85%B8%E5%9C%A8 also has a place in drug development, or is an active ingredient, or participates in the process of drug metabolism, which has a great impact on the efficacy and safety of drugs.
    In the field of materials science, 2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E5%96%B9%E5%95%89 can help develop materials with special properties, such as those with specific optical and electrical properties, for electronic devices, optical instruments, etc. 4-%E7%BE%A7%E9%85%B8%E5%9C%A8 can adjust the chemical stability and mechanical properties of materials, and is indispensable for the preparation of high-performance materials.
    In the field of agriculture, the two may participate in the development of pesticides and fertilizers. 2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E5%96%B9%E5%95%89 can provide a basis for the synthesis of high-efficiency and low-toxicity pesticides, and help the control of crop diseases and pests. 4-%E7%BE%A7%E9%85%B8%E5%9C%A8 or have a positive effect on soil improvement and fertilizer efficiency, promote crop growth and increase yield.
    Furthermore, in the way of scientific research and exploration, the two are important objects for chemical synthesis and reaction mechanism research. By studying their reaction characteristics and interactions, the boundaries of chemical knowledge can be expanded, and the foundation for the creation of new substances and the development of new processes can be laid.
    What is the market price of 2- (trifluoromethyl) quinoline-4-carboxylic acid?
    In today's market, the price of bis (trihydroxymethyl) propane light and tetrahydroxybutyric acid varies according to market conditions and quality.
    Bis (trihydroxymethyl) propane light is mostly used in industry, and is used in chemical synthesis, coatings, adhesives and other industries. It is an essential material. Its price depends on the cost of raw materials, production technology, supply and demand. If the price of raw materials rises, such as oil, formaldehyde, etc., the production cost of bis (trihydroxymethyl) propane light also increases, and its market price also increases. In addition, the new production technology can increase the yield and reduce the cost, resulting in a decrease in its price. Furthermore, if there is a large number of people in the market, but the supply is limited, the price may rise; if the supply exceeds the demand, the price will decline. Recently, the average price in the market is about [X] yuan per kilogram, but the price varies depending on the quality, origin and batch, or fluctuates between [X-Y] yuan per kilogram.
    As for tetrahydroxybutyric acid, it is quite useful in the fields of medicine and biochemical research. Its price is also subject to various factors. The difficulty of obtaining raw materials and the purity of the material are all factors that affect the price. High-purity tetrahydroxybutyric acid is often expensive because it is difficult to mention. And the pharmaceutical industry has strict quality control, and there are few manufacturers in compliance, which also makes its price high. At present, its market price is about [Z] yuan per gram, and the price may vary from [Z - W] yuan per gram due to differences in purity, packaging, and purchase quantity.
    In summary, the market prices of the two change with the market situation. Buyers should carefully observe the market conditions and compare the prices of others to obtain good products at the right price.
    What are the precautions in the preparation of 2- (trifluoromethyl) quinoline-4-carboxylic acid?
    The process of making di- (triethylphenyl) propane-4 -sulfonic acid requires attention and must be treated with caution.
    First of all, the quality of the raw material, whether the raw material is pure or not, is related to the quality of the product. Triethylphenyl materials must be pure. If there are many impurities, the reaction will be difficult, the product will be impure, or the side effects will be overgrown. The quality of the sulfonating agent is also heavy, and its activity and concentration will affect the reaction rate and yield.
    Controlling the temperature of the reaction is the key. If the temperature is too high, the reaction will be too fast, or it will go out of control, and the side effects will increase and the product will decompose. If the temperature is too low, the reaction will be slow, time-consuming and laborious, Each step of the reaction has a suitable temperature, such as sulfonation, suitable for a specific temperature range, in order to obtain the product with excellent yield and purity.
    Furthermore, attention should be paid to the reaction time. Short time, the reaction is not completed, the raw material remains; long time, or the product is deteriorated, only increasing the cost. Therefore, it is necessary to precisely control the time according to the reaction characteristics and monitoring results.
    Stirring should not be ignored. Whether the stirring is uniform or not depends on the mixing of the reactants, the effect of mass and heat transfer. Uneven stirring, local concentration and temperature are different, and the reaction is difficult to be uniform, which affects the quality of the product.
    And the reaction process should be strictly monitored. By means of analysis, such as chromatography, spectroscopy, etc., the degree of reaction can be known in real time, and the conditions can be adjusted in time to ensure that the reaction is as expected.
    Post-treatment is also important. Product separation and purification are related to the purity of the final product. Selection method, removing impurities, to obtain pure products. The step of drying, temperature control and duration, to prevent product decomposition or deliquescence.
    All of these are things to be paid attention to in the production of di- (triethylphenyl) propane-4-sulfonic acid. All links are interconnected, and all have to be careful to form high-quality products.