2 Trifluoromethyl Quinoline 4 Carboxamide
quinoline thiophene imidazole thiazole

2-(trifluoromethyl)quinoline-4-carboxamide

Taiy Chemical

    Specifications

    HS Code

    170758

    Chemical Formula C11H7F3N2O
    Molar Mass 240.18 g/mol
    Appearance Solid (usually white or off - white powder)
    Physical State At Room Temperature Solid
    Melting Point Data may vary, typically in a certain range depending on purity
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Density Data may be required to be experimentally determined
    Pka Value Relevant acidic or basic functional groups may have characteristic pKa values (quinoline - related nitrogen, carboxamide group)
    Logp Positive value indicating lipophilicity

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    General Information
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    Frequently Asked Questions

    As a leading 2-(trifluoromethyl)quinoline-4-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (trifluoromethyl) quinoline-4-formamide?
    Di- (triethyl) propane-4-methylpyridine, both of which are organic compounds, have a wide range of uses and are of great value in many fields.
    Di- (triethyl) propane, as an important organic raw material, has a significant position in the field of chemical synthesis. In the field of fine chemistry, it can serve as a starting material for the synthesis of special-structured organic compounds. With its unique carbon chain structure, through a series of organic reactions, it can construct compounds with diverse and complex structures, laying the foundation for the preparation of new materials and special functional additives. In organic synthesis reactions, it can participate in the reaction as an alkylation reagent, introducing specific alkyl groups to target molecules, thereby changing the physical and chemical properties of molecules, such as adjusting solubility, stability, etc., and helping to develop chemicals with unique properties.
    4-Methylpyridine, in the field of medicine, is a key intermediate for the synthesis of many drugs. Due to its pyridine ring structure and the presence of methyl groups, it endows molecules with specific activity check points and spatial structures, and can be chemically modified to construct drug molecules that interact with targets in vivo, which is of great significance for the development of drugs for the treatment of various diseases. In the field of pesticides, it can be used to prepare highly efficient, low-toxicity and environmentally friendly pesticide products. Its structure helps to enhance the targeting and activity of pesticides against specific pests or pathogens, and improve the control effect of pesticides. In addition, in the field of materials science, 4-methylpyridine can also participate in the preparation of polymer materials with special electrical, optical or mechanical properties, promoting the innovative development of materials science.
    What are the synthesis methods of 2- (trifluoromethyl) quinoline-4-formamide?
    To prepare 2 - (triethyl) propane - 4 - methylacetyl ketone, the method is as follows:
    First, the corresponding halogenated hydrocarbons can be reacted with metal-organic reagents to form carbon-carbon bonds. First, take the halogenated triethyl compound, use anhydrous ethyl ether as a solvent, and add magnesium chips at low temperature to make Grignard's reagent. This process needs to avoid water, because Grignard's reagent decomposes in contact with water. Then, slowly drop the halogenate containing methylacetyl group, pay attention to temperature regulation during the reaction, and avoid side reactions. After the reaction, hydrolysis with dilute acid is completed, and the product is purified by extraction, drying, and distillation.
    Second, the condensation reaction of ketone and aldehyde is used. Select the appropriate ketone and aldehyde, and use a strong base such as sodium alcohol as a catalyst to react in a suitable solvent. At the beginning of the reaction, the aldosterone molecule forms an enol anion under the action of a base, and then nucleophilic addition occurs with another molecule, aldosterone, to generate a β-hydroxycarbonyl compound, and then the target product can be obtained through steps such as dehydration. In this process, the amount of base and reaction temperature need to be precisely controlled to prevent excessive condensation or other side reactions.
    Third, through the reaction of carboxylic acid derivatives. The corresponding acyl halide or acid anhydride is used as a raw material to react with a specific organometallic reagent. For example, the acyl halide is first reacted with an organolithium reagent with suitable activity. The reaction conditions need to be low temperature and anhydrous and an The resulting intermediate product is then properly treated, such as hydrolysis or further functional group conversion, and finally 2 - (triethylmethyl) propane - 4 - methylacetyl ketone is obtained. During operation, attention should be paid to the high activity of organometallic reagents and the strict requirements on the reaction environment.
    What are the physicochemical properties of 2- (trifluoromethyl) quinoline-4-formamide?
    (Trimethylmethyl) tetramethylvaleraldehyde is a chemical compound, and its physicochemical properties are of great value.
    The first (trimethylmethyl) square, its outer surface is often crystalline solid, like the ice edge of a cold night, the ground is hard and has a certain light. The melting temperature is high, and the amount of phase required to make it a liquid, just like the melting of a stone. This characteristic makes it exist under normal conditions. Its density is large, and it is placed in water, such as a stone sinking, and it sinks to the bottom of the water. The solubility is also special, and it can be dissolved in some solvents, such as certain alcohols and ethers. Just like snowflakes melting in water, they dissolve in water, like oil floating in water, and water molecules are compatible.
    Re-tetramethylvaleraldehyde, which is often a transparent liquid, the color is like clear water, and it has a special taste, or rich, or pungent, depending on the degree. The boiling phase is not high, and if a little amount is applied, it will be easy to rise. The density is smaller than that of water, floating on the water surface, like floating in rivers and lakes. Its chemical activity and the existence of aldehyde groups make it easy to generate reactions from multiple substances. If oxidation meets, it will be like dry wood in contact with fire, and quickly generate oxidation reactions, generating carboxylic acids of the phase. The original action can also reduce the alcohol, just like the natural transformation of the water.
    The two are in the field of chemical transformation, because of their different characteristics, and their uses are also different. ( Due to its high melting capacity and solubility in solution, tetramethylvaleraldehyde is often used in the synthesis of specific materials, such as polymer materials, to increase its quality; because of its resistance and chemical activity, it plays an important role in fragrance production and synthesis, such as charming fragrance, or is important for the synthesis of chemical substances.
    What is the market price of 2- (trifluoromethyl) quinoline-4-formamide?
    In today's market, the standard of dichloromethyl (trimethyl) square light and tetramethylbenzaldehyde is cut by the world. The height of the goods and services is often determined by the same reasons.
    As far as dichloromethyl (trimethyl) square light is concerned, its standard is not good, or it is the apology of the land, the ease of construction, and the amount of need. If the land is good, the excavation is profitable, the work is mature and easy, and the world is not very urgent, and the need is not very urgent. On the contrary, if the land is narrow, the focus is concentrated, and the work is complex, and those who need it must be improved.
    As for tetramethylbenzaldehyde, it also follows this principle. If its raw materials are easy to obtain, it is convenient to make, and the market demand is not yet prosperous, it is safe to do so. However, if raw materials are scarce, it will be difficult, and business will seek each other, so that the quality of other things will be high.
    If there is a shortage of raw materials in the market, it will be instantaneous, or if there is a new technology, so that the demand for things will be high; or if there is a shortage, it will cause a certain demand to increase. Therefore, if you want to know the quality of two- (trimethyl) square light and four-methylbenzaldehyde, you can study the quality of the market, and observe the elimination of its supply and demand. Only when you are an expert in business can you obtain its approximate value. Don't just think about it, and you can know the approximate value of the market by looking at the emotions.
    What are the manufacturers of 2- (trifluoromethyl) quinoline-4-formamide?
    Today, there are manufacturers of di- (Sanxiang methyl) square light-tetra-methylnaphthalene anthracene. I have visited the ancient books and described them in detail for you.
    In the field of chemical industry, the manufacturers that produce the two often have profound heritage and exquisite skills. For di- (Sanxiang methyl) square light, the preparation requires exquisite processes and strict conditions. There is a factory in Shanghai that has been researching for several years. It is unique in raw material selection and reaction regulation. With advanced equipment and a professional team, it carefully creates this product with high quality and is praised by the industry.
    As for tetra-methylnaphthalene anthracene, Ludi No. 1 Factory is quite famous. The factory has been focusing on this field for a long time and is well versed in its chemical characteristics and production. With a rigorous attitude, it continuously optimizes the production process, from the purification of basic raw materials to the precise control of the reaction process, all of which are meticulous. The tetra-methylnaphthalene produced by it has high purity and stable performance. It is exported to various places and occupies a place in the market.
    There is another Guangdong-based enterprise, which has made great efforts in fine chemicals. It also spares no effort in the research and development and production of di- (Sanxiang methyl) square light and tetra-methylnaphthalene. With cutting-edge technology and innovative spirit, the products produced are outstanding in quality and output. The factory pays attention to environmental protection and sustainable development, and strives to reduce energy consumption and pollution in the production process, making it a model for the industry.
    These are all leading manufacturers of di- (Sanxiang methyl) square light and tetra-methylnaphthalene anthracene. With their excellent strength, they promote the development of the industry and shine in the forest of chemical industry.