2 Thiophen 2 Ylsulfonyl 1 2 3 4 Tetrahydroisoquinoline
quinoline thiophene imidazole thiazole

2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline

Taiy Chemical

    Specifications

    HS Code

    381269

    Chemical Formula C13H13NO2S2
    Molecular Weight 279.38

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    General Information
    Where to Buy 2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline in China?
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    Frequently Asked Questions

    As a leading 2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2- (thiophen-2-ylsulfonyl) -1, 2, 3, 4-tetrahydroisoquinoline
    2-% (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline is an organic compound. Its physical properties are unique, and it is said in ancient Chinese.
    The state of this compound is either solid at room temperature and pressure. Looking at its color, it is often white-like. When it is pure, it is as white as snow, delicate and uniform. If the light shines, there may be a faint light flickering, like a frosty sun.
    When it comes to the melting point, it is about a certain value. When the temperature gradually rises, to the melting point, this substance is converted from solid to liquid, just like ice disappearing under the warm sun, quietly rheological. The boiling point also has a certain number. When the temperature rises to the boiling point, it turns into a gaseous state and rises, like a cloud.
    Its solubility is also an important physical property. In water, it is quite difficult to dissolve, just like sand and gravel entering water, sinking but not melting. However, in organic solvents, it may have different behaviors. If in ethanol, it can be partially dissolved, just like snowflakes falling on warm wine and gradually melting into it; in organic solvents such as dichloromethane, it dissolves better, can be evenly dispersed and fused into one, if water is emulsified.
    Its density may be different compared to water. If placed in water, it may sink or float, depending on its density. And this thing may have a certain smell, although it is not strong and pungent, but under the fine smell, it also has a unique smell, like a mixture of medicinal fragrance and chemical breath, which is difficult to express and needs to be sensed by sniffing.
    What are the chemical synthesis methods of 2- (thiophen-2-ylsulfonyl) -1, 2, 3, 4-tetrahydroisoquinoline
    To prepare 2 - (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline, the following ancient method can be followed.
    Take 1, 2, 3, 4-tetrahydroisoquinoline as the starting material, which is the key raw material. In a suitable reaction vessel, add an appropriate amount of organic solvent, such as dichloromethane, etc., to fully dissolve 1, 2, 3, 4-tetrahydroisoquinoline to form a uniform solution.
    Prepare thiophene-2-sulfonyl chloride and slowly add it to the above solution. In this process, it is necessary to pay attention to the temperature of the reaction, and it is advisable to control the temperature in the low temperature range, such as between 0 ° C and 5 ° C, which can be achieved by ice bath. Thiophene-2-sulfonyl chloride and 1,2,3,4-tetrahydroisoquinoline can undergo nucleophilic substitution.
    In order to promote the smooth progress of the reaction, it is often necessary to add a certain amount of alkali, such as triethylamine. The base can neutralize the acid generated by the reaction and promote the positive progress of the reaction. During the reaction, keep stirring to make the reactants fully contact.
    After the reaction has passed for several hours, the reaction process is monitored by thin layer chromatography and other methods. When the raw material point basically disappears, the reaction After that, the reaction mixture is poured into an appropriate amount of water and extracted with an organic solvent such as dichloromethane. Extract several times and combine the organic phases.
    The organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove the moisture. Subsequently, the organic solvent is removed by reduced pressure distillation to obtain a crude product.
    The crude product is purified by column chromatography and other methods. A suitable eluent is selected, such as the mixture of petroleum ether and ethyl acetate. After separation and collection, a pure 2 - (thiophene-2-ylsulfonyl) -1,2,3,4 -tetrahydroisoquinoline product can be obtained. This is one of the methods for preparing this substance. During operation, attention should be paid to the conditions and details of each step to ensure the smoothness of the experiment and the purity of the product.
    2- (thiophen-2-ylsulfonyl) -1, 2, 3, what is the main use of 4-tetrahydroisoquinoline
    2-% (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline, this is an organic compound. Its main uses are related to many fields.
    In the field of medicinal chemistry, it is often used as a key intermediate in synthesis. It can build a complex drug molecular structure through a series of reactions with its specific chemical structure. Because of its unique functional groups, it can participate in a variety of chemical reactions, such as nucleophilic substitution, redox, etc., to help synthesize compounds with specific biological activities or drugs with therapeutic potential for specific diseases.
    In the field of materials science, it also has applications. Due to its molecular structure, it is endowed with special physical and chemical properties, or it can be used to prepare materials with unique properties. For example, by modifying its structure to have specific optoelectronic properties, it can be used in the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells and other fields, providing possibilities for material performance optimization and new function development.
    In organic synthetic chemistry, as an important synthetic block, it can provide a structural basis for the construction of organic molecules. Chemists can design and implement various synthetic strategies according to their structural characteristics, expand the molecular library of organic compounds, lay the foundation for the creation and performance research of new substances, and promote the continuous development and progress of organic synthetic chemistry.
    2- (thiophen-2-ylsulfonyl) -1, 2, 3, what is the market outlook for 4-tetrahydroisoquinoline
    2-% (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline is one of the organic compounds. Looking at its market prospects, it needs to be considered from various factors.
    First describes its use. This compound is used in the field of pharmaceutical chemistry, or can be used as a pharmaceutical intermediate to help the research and development of new drugs. Today, the pharmaceutical industry is booming, and the demand for characteristic intermediates is increasing day by day. If it shows unique activity and advantages in drug creation, it will attract the attention of many pharmaceutical companies, and the market demand is expected to grow.
    Second on the field of chemical materials. With the progress of materials science, the demand for special structural compounds also changes. If 2% (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline can give the material special properties, such as improved material stability, optical properties, etc., chemical material manufacturers may favor it and open up a market.
    Furthermore, the difficulty and cost of synthesis are also key. If the synthesis process is complex and expensive, even if it is widely used, its marketing activities will be hindered. On the contrary, if the synthesis path can be optimized and the cost can be reduced, its market competitiveness will be enhanced.
    Review the scientific research trends. The scientific research community has been exploring new compounds. If the relevant research results of this compound are fruitful and reveal more potential application value, it will also promote the market demand for it.
    Overall, there are many variables in the market outlook for 2% (thiophene-2-ylsulfonyl) -1,2,3,4-tetrahydroisoquinoline. However, if we can do a good job in application development, cost control, scientific research promotion, etc., we may be able to win a place in the market, and the prospects may be promising.
    2- (thiophen-2-ylsulfonyl) -1, 2, 3, 4-tetrahydroisoquinoline in which areas
    2-% (thiophen-2-ylsulfonyl) -1,2,3, 4-tetrahydroisoquinoline, is an organic compound. This compound has its uses in many fields.
    In the field of medicine, it shows potential medicinal value. Due to the unique chemical structure of the compound, it may interact with specific targets in organisms. After research, it has been found that it may affect the biological pathways related to certain diseases, such as those involved in cell signaling. For example, in the study of tumor diseases, it may affect the proliferation and apoptosis of tumor cells by regulating the activity of related proteins, and then provide new opportunities for the development of anti-tumor drugs.
    In the field of materials science, 2-% (thiophen-2-ylsulfonyl) -1,2,3, 4-tetrahydroisoquinoline also has applications. Due to its specific physical and chemical properties, it can be used to prepare functional materials. For example, in photoelectric materials, it may affect the photoelectric conversion efficiency of materials. Introducing it into a specific material system can change the electron cloud distribution of the material, thereby regulating the absorption and emission characteristics of the material. It is expected to be applied to the manufacture of optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve the performance of the device.
    In the field of organic synthesis, this compound can be used as an important synthesis intermediate. Because its structure contains multiple active check points, it can be combined with other organic compounds through various chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to construct more complex organic molecular structures. Chemists can use it as a starting material to design and synthesize a series of organic compounds with specific functions, enrich the variety of organic compounds, and expand the methods and paths of organic synthesis.