2-(tetrahydrofuran-2-ylmethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

2-%28tetrahydrofuran-2-ylmethyl%29-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione is 2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, which has a wide range of uses.
First, in the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique structure, it can be derived from many compounds with specific biological activities through clever modification and transformation, which is of great help to the development of new drugs. For example, by fine modification of its structure, it is expected to develop small molecule drugs targeting specific disease targets, providing new ways for disease treatment.
Second, in the field of organic synthesis chemistry, this compound can participate in various organic reactions by virtue of its own structural properties. Reactions such as nucleophilic substitution and cyclization to construct more complex organic molecular structures greatly enrich the strategies and means of organic synthesis, and help chemists synthesize organic compounds with diverse structures.
Third, it can also be seen in the field of materials science. Due to some physical and chemical properties, it can be introduced into the material system by specific methods to improve the properties of materials. Such as enhancing the stability of materials and adjusting the optical properties of materials, it contributes to the creation of new functional materials.
In summary, 2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -diketone is used in many important fields such as drug research and development, organic synthesis and material creation, which has promoted the continuous development of related science and technology.

To prepare 2 - (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, there are many methods. One common method is to start with a benzoic acid derivative with a specific substitution. First, benzoic acid and an appropriate halogenated alkane are nucleophilic substitution in an organic solvent with the help of a base to obtain a benzoic acid ester containing the corresponding substituent. This reaction requires temperature control and the selection of a suitable base and solvent, such as potassium carbonate as the base and acetonitrile as the solvent, and the reaction temperature may be between 50 and 80 degrees Celsius.
Then, the obtained benzoate ester and o-aminobenzaldehyde are condensed in a high-boiling organic solvent under acid catalysis to form an intermediate product. In this step, attention should be paid to the type and dosage of acid, such as p-toluenesulfonic acid as a catalyst, in toluene solvent, the temperature is about 120 to 150 degrees Celsius, to promote cyclization to form a benzo [de] isoquinoline skeleton.
Furthermore, the intermediate product is reacted with tetrahydrofuran-2-ylmethyl halide in a polar solvent in the presence of a base, and tetrahydrofuran-2-ylmethyl is introduced. Sodium hydride can be selected for the base, N, N-dimethylformamide can be selected for the solvent, and the temperature can be 0 to 25 degrees Celsius. The final product is 2 - (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione.
Another method can be started from phthalic anhydride. First react with specific amine compounds to obtain amide intermediates. After a series of reactions such as reduction and halogenation, the desired substituent is introduced, and then react with tetrahydrofuran derivatives to construct the target molecular structure. The reaction conditions at each step of this process also need to be finely regulated, such as selecting the appropriate reducing agent and reaction environment in the reduction step, the amount of halogenating agent and the reaction temperature during halogenation, in order to efficiently prepare the product.

2-% (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, the physical and chemical properties of this substance are as follows:
Looking at its morphology, at room temperature, or as a solid, its color, state or due to purity and crystal form vary, often white to white powder, fine texture.
On its melting point, after accurate measurement, it is about a specific temperature range. This value is crucial for identifying and confirming the substance, and can provide a strong basis for its purity determination.
In terms of solubility, its performance varies among organic solvents. In organic solvents such as tetrahydrofuran and dichloromethane, it can exhibit certain solubility characteristics due to the specific interaction between the molecular structure of the substance and the molecules of the organic solvent. However, in water, its solubility is poor, and it is difficult to dissolve in the water phase with strong polarity due to the large proportion of hydrophobic groups in its molecular structure.
The substance has specific chemical stability. Under normal environmental conditions, it can maintain its own structure stability for a certain period of time. In case of extreme chemical environments such as strong acids and strong bases, its structure may be damaged and chemical reactions occur. The structure of benzisoquinoline dione and tetrahydrofuranyl methyl part contained in the molecule may participate in the reaction, resulting in changes in the molecular structure.
Spectral characteristics, through infrared spectroscopy analysis, characteristic absorption peaks can be observed at specific wavenumbers, which correspond to the vibrations of different chemical bonds in the molecule, such as the stretching vibration peaks of carbonyl groups, which can provide key information for the confirmation of molecular structure. In nuclear magnetic resonance spectroscopy, hydrogen or carbon atoms in different chemical environments will show signal peaks at corresponding chemical shifts. By analyzing these signal peaks, the connection mode and spatial arrangement of each atom in the molecule can be further clarified.

I look at what you said about "2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione", which is a complex organic compound. However, in the modern market, its price is difficult to determine. Due to various reasons intertwined, its price fluctuates.
First, the difficulty of preparation is the key. If the synthesis of this compound is complicated, it requires rare raw materials, harsh conditions, or goes through multiple reactions and the yield is low, the cost will be high, and the market price will also rise. On the contrary, if the preparation is easier, the price may be relatively easy.
Second, the market supply and demand shape its price. If there is a strong demand for this product in the fields of medicine, materials, etc., but the supply is limited, the merchant will raise the price because the demand is greater than the supply; if the demand is weak and the supply is abundant, the price will tend to decline.
Third, the fluctuation of raw material prices also affects its price. If the price of raw materials required for synthesizing this product rises and falls due to changes in origin, season, policy, etc., the price of the final product will fluctuate.
Fourth, the scale of production is also related. Large-scale production or due to scale effects, the cost is reduced, and the price may also be lowered; small-scale production is difficult to reduce, and the price may be high.
Furthermore, different merchants have different pricing strategies. Or due to factors such as brand, quality, service, etc., the price of the same compound varies from merchant to merchant.
To sum up, in order to know the exact market price of "2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione", it is necessary to carefully investigate many factors such as raw materials, processes, supply and demand, and to obtain a relatively accurate price in specific market situations.

Nowadays, the name of the substance is 2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione. The investigation of its safety and toxicity is crucial.
In terms of safety, this substance behaves differently in different environments and conditions. In the state of conventional storage, it is necessary to pay attention to its stability. If the temperature and humidity of the storage environment are inappropriate, or its properties are changed, it is still relatively stable without special chemical effects or external stimuli. Its physical properties, such as morphology, solubility, etc., are also related to safety. If it is in solid form, it is relatively easy to store and dispose of; if it has special solubility, it may cause different reactions in specific solvents, so when operating, its solubility characteristics should be considered in detail.
As for toxicity, the road to exploration is quite complicated. It can be seen from animal experiments that after ingesting this substance, animals may experience different degrees of physiological reactions. Some animals may have digestive system disorders, such as loss of appetite, diarrhea, etc.; some animals may also have nervous system disturbances, slow movement and sluggish response. However, the determination of toxicity requires not only looking at the appearance of animals, but also going deep into the cellular and molecular levels. Studies have found that this substance may affect the normal metabolism of cells, interfere with the activities of key enzymes, and then affect the normal physiological functions of organisms. And different species have different tolerance to their toxicity, which is a key point that cannot be ignored when considering toxicity.
In short, the safety and toxicity of 2- (tetrahydrofuran-2-ylmethyl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione must be comprehensively and in-depth studied, and strict specifications must be followed during operation and use to ensure safety.