As a leading 2-Quinolinecarboxylic acid, 6-cyano-1,4-dihydro-4-oxo-, methyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
2 - Quinolinecarboxylic acid, 6 - cyano - 1,4 - dihydro - 4 - oxo -, methyl ester What are the chemical properties
6-Cyano-1,4-dihydro-4-oxo-2-quinoline carboxylic acid methyl ester, this is an organic compound. Looking at its structure, it has a quinoline parent nucleus, with cyano, carbonyl and methyl ester groups added at specific positions.
In terms of its physical properties, it may be a solid under normal conditions, but it has a certain melting point due to the actions of van der Waals forces and hydrogen bonds between molecules. And because it contains polar functional groups, it may have a certain solubility in polar solvents such as alcohols and ketones, but limited solubility in non-polar solvents such as alkanes.
In terms of chemical properties, cyanyl groups have high reactivity and can participate in a variety of reactions. For example, under appropriate conditions, cyanyl groups can be hydrolyzed into carboxyl groups or converted into amine groups by reduction reactions. Carbonyl groups in the 1,4-dihydro-4-oxo structure can undergo nucleophilic addition reactions, such as reacting with alcohols to form acetals or ketals, and reacting with amines to form imines. Methyl ester groups can undergo hydrolysis reactions to generate corresponding carboxylic acids and methanol under the catalysis of acids or bases; they can also participate in transesterification reactions, and react with other alcohols to form new esters under the action of catalysts.
The quinoline parent nucleus has a certain aromaticity due to its conjugated system, which can undergo electrophilic substitution reaction, and the reaction check point is affected by the localization effect of substituents.
Due to its diverse chemical properties, this compound is used in the field of organic synthesis or as a key intermediate to construct complex organic molecular structures, and may have potential applications in pharmaceutical chemistry and other fields.
2 - Quinolinecarboxylic acid, 6 - cyano - 1,4 - dihydro - 4 - oxo -, methyl ester What are the common uses
6-Cyano-1,4-dihydro-4-oxo-quinoline-2-carboxylic acid methyl ester, which is a crucial compound in the field of organic synthesis. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to create many biologically active drugs. Due to its specific structure, it has the potential to interact with targets in organisms. By ingeniously modifying the structure, drugs with different effects such as antibacterial, anti-inflammatory, and anti-tumor can be developed.
In the field of pesticide chemistry, it also has important applications. It can be used as a raw material to prepare pesticides with high insecticidal and bactericidal properties. With its unique chemical structure, it can precisely act on the specific physiological processes of pests or pathogens to achieve the purpose of efficient control, and has relatively little impact on the environment, which is in line with the current trend of green pesticide development.
In the field of materials science, this compound can also play a role. Or participate in the synthesis of materials with special optical and electrical properties, such as for the preparation of organic Light Emitting Diode (OLED) materials, because of its structural properties, it may have a positive impact on the key properties such as material luminous efficiency and stability, thereby promoting the improvement of related material properties.
Furthermore, in the study of organic synthesis methodology, it is often used as a model substrate. Chemists have promoted the development of organic synthetic chemistry by exploring novel synthesis routes and optimizing reaction conditions using it as a starting material, providing new ideas and methods for the synthesis of more complex organic compounds.
2 - Quinolinecarboxylic acid, 6 - cyano - 1,4 - dihydro - 4 - oxo - methyl ester
The synthesis of 6-cyano-1,4-dihydro-4-oxyquinoline-2-carboxylic acid methyl ester requires a chemical reaction process of several steps. The choice of starting materials is crucial to the success or failure of the synthesis. Quinoline derivatives with specific substituents are often used as starting materials, which can be commercially available or made according to existing organic synthesis methods.
The first step may require the introduction of a cyanide group. A suitable cyanide reagent, such as potassium cyanide or sodium cyanide, can be selected to interact with the starting quinoline derivative under specific reaction conditions. This reaction may need to be carried out in an organic solvent, such as dimethylformamide (DMF) or dichloromethane, and appropriate alkali substances are required to facilitate the reaction. The alkali can be selected from potassium carbonate or sodium carbonate, etc. Its function is to assist the cyanyl group to replace the functional group at a specific position, so as to introduce the cyanyl group at the 6 position of the quinoline ring.
Second steps to construct a 1,4-dihydro-4-oxo structure. This step often requires oxidation and cyclization reaction steps. A suitable oxidizing agent, such as manganese dioxide or chromium trioxide, can be used to oxidize the quinoline derivative under appropriate solvent and temperature conditions to form a specific unsaturated ketone structure. Then, the structure of 1,4-dihydro-4-oxo generation is achieved by intramolecular cyclization reaction. The cyclization reaction may require specific catalysts, such as concentrated sulfuric acid or Lewis acid, to promote intramolecular rearrangement and cyclization.
The last step is to form a methyl ester. In this step, methanol and suitable esterification reagents, such as dichlorosulfoxide or oxalyl chloride, can be selected. First, esterification reagents react with 6-cyano-1,4-dihydro-4-oxyquinoline-2-carboxylic acid to form an active acid chloride intermediate, and then this intermediate reacts with methanol to obtain the target product 6-cyano-1,4-dihydro-4-oxyquinoline-2-carboxylic acid methyl ester. After the reaction, the separation and purification steps are required to obtain a purified product. Commonly used separation methods include column chromatography or recrystallization to ensure that the purity of the product meets the requirements.
2 - Quinolinecarboxylic acid, 6 - cyano - 1,4 - dihydro - 4 - oxo -, methyl ester What is the price range in the market
I look at your question, but I am inquiring about the market price of 6-cyano-1,4-dihydro-4-oxyquinoline-2-carboxylic acid methyl ester. However, the price of this product often changes due to many reasons, and it is difficult to determine a certain number.
First, the supply is different, and the price is different. If you get it from a good factory, the quality will be high or high; if you source from an ordinary manufacturer, the price may be slightly lower. Second, the quantity also affects the price. If you buy a large quantity, you may be given a discount, and the price is low; if you buy a small quantity, the price may be high. Third, the price varies depending on the time. Market supply and demand change, and prices follow suit. When the demand is high, the price tends to rise; when the supply is high, the price tends to fall.
As far as I know, the price of this chemical in the market may range from tens to hundreds of yuan per gram. If the purchase quantity exceeds 100 grams, the price per gram may drop to tens of yuan. However, this is only a rough estimate. The actual price should be consulted with the chemical supplier, and his quotation shall prevail. If you want to know the exact price, you can check it in detail on the chemical product trading platform, or directly ask the relevant merchants to get the accurate price.
2 - Quinolinecarboxylic acid, 6 - cyano - 1,4 - dihydro - 4 - oxo -, methyl ester What are the storage conditions
6-Cyano-1,4-dihydro-4-oxo-quinoline-2-carboxylic acid methyl ester, this is an organic compound. Its storage conditions are crucial to its stability and quality.
According to the concept of "Tiangong Kaiwu", everything needs to be suitable for its existence. This compound should be stored in a cool place, away from heat sources and open flames. It is easy to cause molecular activity due to heat, or the risk of decomposition and deterioration. The temperature should not exceed 25 ° C. If it is too high, its structure may be damaged.
And should be placed in a dry place, away from moisture. Water vapor is easy to react with compounds, or cause reactions such as hydrolysis, which damage their purity and characteristics. Relative humidity should be controlled at 40% - 60%.
In addition, it needs to be stored in a closed container to prevent excessive contact with air. Oxygen, carbon dioxide, etc. in the air, or react with it. Especially this compound contains active groups such as cyanide groups and ester groups, which are more susceptible.
When stored, it should also be separated from oxidants, acids, bases, etc. Due to its chemical properties, when encountering such substances, it may react violently and cause danger. The quality and stability of methyl 6-cyano-1,4-dihydro-4-oxo-quinoline-2-carboxylate can be guaranteed by following the above storage conditions for subsequent experiments and production.