Chemical Formula | C11H5F3N2 |
Molecular Weight | 222.17 |
Appearance | Solid (predicted) |
Boiling Point | 304.6°C at 760 mmHg (predicted) |
Melting Point | 120 - 122°C |
Density | 1.427 g/cm³ (predicted) |
Logp | 3.45 (predicted) |
Flash Point | 138°C (predicted) |
Solubility | Soluble in organic solvents like DMSO, DMF |
Pka | N/A (no acidic or basic hydrogens in typical pH range) |
What are the chemical properties of 4- (trifluoromethyl) -2-quinolinocarbonitrile?
4- (trichloromethyl) - 2 -difluoromethyl phenyl sulfide, this is an organic compound. Its chemical properties are quite complex and have the following characteristics:
First, due to the presence of halogen atoms in the molecule, it exhibits a certain polarity. Halogen atoms have high electronegativity and cause uneven distribution of molecular electron clouds. This polarity has a profound impact on their physical and chemical properties. For example, in terms of solubility, compared with non-polar compounds, they are more soluble in some polar solvents.
In terms of reactivity, halogen atoms can participate in many nucleophilic substitution reactions. Nucleophilic reagents are easy to attack and connect to carbon atoms with halogen atoms, and halogen atoms leave as leaving groups to form new compounds. For example, if a nucleophilic reagent such as sodium alcohol exists, the halogen atom can be replaced by an alkoxy group to obtain a new substance containing ether bonds.
Furthermore, the phenyl ring structure in the compound gives it aromaticity. The benzene ring conjugate system is stable, so that the compound has special stability and reaction characteristics for oxidation and addition reactions to a certain extent. Under specific conditions, electrophilic substitution reactions on the benzene ring can occur, such as halogenation, nitration, sulfonation, etc. For example, under the action of a suitable catalyst, it can react with bromine and introduce bromine atoms on the benzene ring.
In addition, the sulfur ether structure containing sulfur atoms also has unique properties. Sulfur atoms have solitary pairs of electrons and can participate in the reaction as electron donors, which can be oxidized to form sulfoxides or sulfones. In case of a suitable oxidant, such as hydrogen peroxide, the thioether bond will be oxidized, and the valence state of the sulfur atom will increase to form the corresponding sulfoxide or sulfone.
Due to the variety of special structures and atoms, 4- (trichloromethyl) -2 -difluoromethyl phenylene sulfide can be used as a key intermediate in the field of organic synthesis, used to prepare various functional organic compounds, and has potential application value in many fields such as materials science and medicinal chemistry.
What are the common synthesis methods of 4- (trifluoromethyl) -2-quinolinocarbonitrile?
The common synthesis method of triethyl-2-pentenoate ethyl ester is an important task in organic synthesis. There are many methods, each with its advantages and disadvantages, and often depends on the specific situation.
One is based on the reaction of halogenated hydrocarbons and alkenolates. First, the halogenated hydrocarbons interact with metal reagents to form organometallic intermediates, such as Grignard reagent or lithium reagent. Then, this intermediate is contacted with the enolate, and the nucleophilic substitution reaction is carried out to obtain the target product. For example, triethyl-2-pentenoate can be obtained by reacting the enolates of ethyl pentenoate with a suitable halogenated ethane in a suitable solvent, such as tetrahydrofuran, at low temperature and under the protection of inert gas. The advantage of this approach is that the reaction conditions are milder and the yield is acceptable; the disadvantage is that the preparation of halogenated hydrocarbons may require multiple steps, and the organic metal reagents are more active, so the operation needs to be cautious.
Second, it is achieved by ester condensation reaction. Using ethyl acetate and other esters as starting materials, under the catalysis of strong bases such as sodium ethyl alcohol, the condensation of clayson esters occurs. The two-molecule esters interact to form β-ketoate. After appropriate modification, such as the introduction of ethyl in an alkylation reaction, the final product can be obtained. This process requires attention to the amount of alkali and the reaction temperature to avoid overreaction. The advantage is that the raw materials are common and easy to obtain, and the reaction steps are logical; the disadvantage is that the total yield is limited due to the multi-step reaction, and the separation and purification are cumbersome.
Third, the addition reaction of olefins is used. Appropriate olefins and electrophilic reagents containing ester groups are added under the action of catalysts. For example, pentene and halide containing ethyl ester groups are added to the target product in the presence of transition metal catalysts and ligands such as palladium. This method relies on high-efficiency catalysts, and although carbon-carbon bonds can be formed in one step, the catalyst cost is high and the reaction conditions are strictly controlled.
In which fields is 4- (trifluoromethyl) -2-quinolinocarbonitrile used?
"Tiangong, (Sanxiang Methyl) - 2-Light-ethylene cotton is used in many fields.
It is used in the field of manufacturing, (Sanxiang Methyl) - 2-Light-ethylene cotton has its own characteristics and can become a beautiful product. Its soft ground, feeling good, and the clothes are worn on the body, comfortable and usual. And its color is beautiful, it does not fade for a long time, and it adds a lot of color to the things. It can be used as a regular garment or a new garment, all of which can be used for special performance.
In the world of, this material is also very popular. Because of its density, it is easy to wear and lead, and the case is refined and nuanced, and it flows naturally. < Br >
In the field, (Sanxiang Methyl) - 2-light cotton can be used for a wide range of purposes. It can be used as a window, a room light, and its soft light can also create a beautiful atmosphere in the room; it can be used as a wall, with its exquisite sense of design, add empty air, and create an elegant environment.
In terms of aesthetics, this cotton can be used as a raw material for a variety of crafts. The beautiful shape of the crafted product has both a useful value, such as fine support, small sachets, etc., which can show its special charm.
Therefore, (Sanxiang methyl) - 2-light ethylene cotton is used in many fields such as manufacturing, manufacturing, manufacturing and industrial beauty, etc., all of which play an important role in their characteristics, adding color to each line of work.
What is the market prospect of 4- (trifluoromethyl) -2-quinolinocarbonitrile?
In today's world, the market prospects of trimethylolpropane and diphenylformamide are related to the rise and fall of industry and commerce, and cannot be ignored.
Guanfu trimethylolpropane has a wide range of uses and is indispensable in coatings, polyester, polyurethane and other industries. In today's world, the paint industry is booming and prosperous, and people are increasingly seeking for home decoration and utensils painting, which has created a vast market for trimethylolpropane. And the polyurethane industry is also in the ascendant, which is widely used in furniture, automobile interiors, building insulation and other fields. As a key raw material, the demand for trimethylolpropane is also rising. In addition to the new technology, new application fields may have opportunities to develop. The market prospect of trimethylolpropane is quite promising, and it is expected to rise in volume and price with the progress of various industries.
As for diphenylformamide, it is also an important raw material in the pharmaceutical, pesticide, dye and other industries. The pharmaceutical industry is related to people's livelihood and health, and is always valued by the world. In the process of developing new drugs, diphenylformamide may be helpful, and with the increase of population and the people's growing desire for health, the expansion of the pharmaceutical market is difficult to stop, and the demand for diphenylformamide should also increase. In terms of pesticides, in order to ensure abundant agricultural production and deal with pests, the demand for pesticides is also rising steadily. Although the dye industry is affected by environmental regulations, with technological innovation, environmentally friendly dyes are on the rise. If diphenylformamide can fit this trend, it is also expected to gain a place in the market.
In summary, trimethylolpropane and diphenylformamide play an important role in their respective related industries. Although there may be some challenges, such as environmental regulations and market competition, in general, with the development of the industry and the progress of technology, its market prospect is quite bright, and it is expected to develop its talents in the business sea and bring rich benefits to the industry.
What are the storage conditions for 4- (trifluoromethyl) -2-quinolinocarbonitrile?
The storage conditions of (triethyl) -2-difluoroacetylbenzene are the key elements related to the storage of this drug. This drug needs to be placed in a cold place to avoid the disturbance of temperature. The definition of cold place probably refers to between two and ten degrees Celsius. In this temperature range, the chemical structure of the drug can be kept stable, and it is not easy to decompose and deteriorate due to temperature fluctuations.
and must be sealed. Sealed to prevent external moisture, air, etc. from coming into contact with the drug. Moisture entering the interior may cause the drug to deliquescent, changing its physical properties, thereby affecting the efficacy of the drug; in the air, oxygen and other components may also react with the drug, damaging the quality of the drug.
Furthermore, it needs to be stored in shade away from light. Light, especially strong light, contains high energy photons, or induces a photochemical reaction of a drug. Once this reaction is initiated, the active ingredients of the drug may be destroyed, and the curative effect will also be damaged. Therefore, choose a place protected from light, such as brown bottles containing drugs, or stored in opaque containers or cabinets, to reduce the effect of light on the drug.
In summary, (triethyl) -2-difluoroacetylbenzene should be stored in a cold place of two to ten degrees Celsius, sealed and protected from light, in order to maintain its quality and efficacy for a long time.