2-(pyridin-3-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

2-%28pyridin-3-yl%29-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione is 2- (pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, which has a wide range of uses.
In the field of medicinal chemistry, it is often the key intermediate for the creation of new drugs. Due to its unique chemical structure, other functional groups can be introduced by organic synthesis, and then compounds with specific biological activities can be constructed. Some drugs developed based on this may have positive effects on the treatment of specific diseases. For example, for some intractable diseases, they can be precisely designed to be highly compatible with the target of lesions in the body and achieve the purpose of treatment. < Br >
In the field of materials science, it also has applications. Due to its structural stability and special optical and electrical properties, it can be used to prepare optoelectronic materials. Such materials may exhibit excellent properties in organic Light Emitting Diodes (OLEDs), solar cells and other devices, such as improving the luminous efficiency of the device and enhancing the photoelectric conversion efficiency, providing new opportunities for the development of materials science.
In addition, in the field of scientific research and exploration, as an important building block for organic synthesis, chemists use it to explore novel chemical reaction mechanisms and develop innovative synthesis methods. Through in-depth study of their reaction characteristics, the knowledge boundary of organic chemistry is expanded, and new paths are opened for the synthesis of more complex compounds.

2- (Pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione is one of the organic compounds. Its physical properties are quite important, let me tell you one by one.
Looking at its appearance, it often appears solid at room temperature and pressure. Due to the force between molecules, its structure tends to be stable and it is not easy to flow. As for the color, it is mostly white or white-like powder, which makes it easy to distinguish among many substances.
When talking about the melting point, it is about a specific temperature range. This temperature limit is crucial for the transformation of its physical form. When the temperature rises near the melting point, the thermal motion of the molecule intensifies, which is enough to overcome the constraints of the lattice energy, and then gradually changes from the solid state to the liquid state. The exact value of this melting point varies slightly due to factors such as material purity, but the approximate range can be used for reference as the basis for identification and application.
Solubility is also one of its important physical properties. In common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it has a certain solubility. This is because the groups contained in the molecular structure can form specific interactions with the solvent molecules, such as hydrogen bonds, van der Waals forces, etc., which can promote their dissolution. However, in water, its solubility is not good, because the hydrophobic part of the compound accounts for a large proportion, and the interaction with water molecules is weak.
In addition, the density of the compound also has a certain value. Density reflects the mass per unit volume of a substance, and in practical applications, it is related to the dosage, storage and transportation of the substance. Although the specific value of its density needs to be accurately measured to determine, the characteristics of its relative density can help determine its distribution when mixed with other substances.
In summary, the physical properties of 2- (pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, such as appearance, melting point, solubility and density, are of great significance to its research, identification and practical application, laying the foundation for its application in chemistry, medicine and other fields.

The preparation of 2- (pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione can be done according to the following ancient method.
First take an appropriate amount of 3-pyridyl boronic acid and 1,8-naphthalic anhydride as raw materials. These two are in the reaction system and are the key starting materials. The reaction environment is constructed with anhydrous organic solvents, such as toluene, dioxane, etc. These solvents can provide suitable dissolution and dispersion conditions for the reaction, so that the reactants can be fully contacted.
Then add palladium-based catalysts, such as tetra (triphenylphosphine) palladium, etc. The palladium catalyst has a key catalytic efficiency in the reaction, which can significantly reduce the activation energy of the reaction and promote the efficient progress of the reaction. It is accompanied by an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, etc. The function of alkali is to adjust the pH of the reaction system and help the smooth operation of the catalytic cycle.
Then, the reaction system is heated to a suitable temperature, usually controlled between 80-120 ° C. The appropriate temperature can give the reactant molecules enough energy to greatly increase the effective collision frequency and speed up the reaction rate. Under continuous stirring, the reaction can be fully carried out, and stirring can ensure that the reactants are evenly mixed, so that the reaction can be efficiently advanced in the homogeneous system.
After the reaction is completed, the product is purified by conventional post-treatment. After extraction, the product is extracted from the reaction mixture with an organic solvent that is not miscible with water, such as ethyl acetate, etc., to achieve preliminary separation. Then purified by column chromatography, the appropriate silica gel filler and eluent, such as petroleum ether and ethyl acetate mixed in a certain proportion, according to the difference in distribution coefficients between the product and impurities in the stationary phase and the mobile phase, to achieve fine separation of the product and impurities, and finally obtain a pure 2 - (pyridine-3 - yl) -1H - benzo [de] isoquinoline-1,3 (2H) -dione product.

I don't know the price range of "2- (pyridin-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione" in the market. This is a more professional chemical substance, and its price is affected by many factors. First, the purity has a great impact on the price. High purity has a high price, and low purity has a low price. Second, the scale of production also plays a role. Large-scale production leads to lower costs, and prices may decrease; small-scale production has high costs, and prices will increase. Third, the relationship between market demand is very important. If demand is strong and supply is small, prices will rise; if demand is weak and supply is large, prices will fall. In addition, the complexity of the production process and the difficulty of obtaining raw materials will all affect its price. However, it is difficult for us to determine the specific price range, or we need to check in detail on the chemical product trading platform, relevant industry information office, or consult professional chemical practitioners before we can obtain a more accurate price range.

2-%28pyridin-3-yl%29-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione is 2- (pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione, which is an organic compound. Precautions for the safety of this substance are detailed as follows:
This substance may be toxic. When operating, be sure to wear appropriate protective clothing, such as laboratory clothes, gloves, and protective eye masks to prevent it from contacting the skin and eyes. If you accidentally touch the skin, rinse with plenty of water immediately. If you feel unwell, seek medical attention immediately. If you come into contact with the eyes, open the eyelids immediately, rinse with flowing water or normal saline, and then seek medical attention as soon as possible.
Furthermore, it is crucial to operate in a well-ventilated place. Because of its possible evaporation of harmful gases, good ventilation can discharge harmful gases in time, reduce the concentration of harmful substances in the air, and avoid inhalation. If dust is generated during operation, effective protective measures should also be taken, such as wearing a dust mask to prevent dust from being inhaled in the body.
In terms of storage, it should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent dangerous reactions. The storage area should be equipped with suitable materials to contain leaks.
In addition, personnel handling this compound need to be professionally trained and familiar with its characteristics and safe operation procedures. Waste generated during the experimental process must not be discarded at will, and must be properly disposed of in accordance with relevant regulations to prevent pollution of the environment.
In short, the treatment of 2- (pyridine-3-yl) -1H-benzo [de] isoquinoline-1,3 (2H) -dione compounds must be treated with caution and strictly follow safe operation practices, so as to ensure the safety of personnel and the environment from harm.