Chemical Formula | C15H11N |
Molar Mass | 203.26 g/mol |
Appearance | Solid |
Color | Yellowish |
Odor | Weak aromatic odor |
Melting Point | 79 - 81 °C |
Boiling Point | 360 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, chloroform |
Density | 1.162 g/cm³ |
Flash Point | 175 °C |
Stability | Stable under normal conditions |
What are the main uses of 2-Phenylquinoline?
2-Phenylquinoline is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
First, in the field of materials science, 2-phenylquinoline can be used as a luminescent material. Because of its unique optical properties, it can emit light of specific wavelengths, so it is often used in the preparation of organic Light Emitting Diodes (OLEDs). OLEDs have many advantages such as self-luminescence, wide viewing angle, and fast response speed, and are increasingly important in display technology. 2-Phenylquinoline, as one of the luminescent layer materials, can effectively improve the luminous efficiency and stability of OLEDs, making the display screen clearer and brighter.
Second, in the field of medicinal chemistry, 2-phenylquinoline also shows potential medicinal value. Studies have found that its structure can be modified to fit specific biological targets, and has biological activities such as antibacterial, anti-inflammatory, and anti-tumor. For example, some compounds derived from 2-phenylquinoline as the parent nucleus have been experimentally verified to have significant inhibitory effects on some tumor cell lines, providing a possible direction for the development of new anti-tumor drugs.
Furthermore, in the field of analytical chemistry, 2-phenylquinoline can be used as a fluorescent probe. Using its selective identification of specific ions or molecules and the characteristics of fluorescence signal change, sensitive detection of heavy metal ions and reactive oxygen species in the environment can be realized. This detection method has the advantages of high sensitivity, good selectivity, and simple operation, and has broad application prospects in environmental monitoring and biomedical diagnosis.
In addition, in the field of organic synthesis, 2-phenylquinoline, as an important synthesis intermediate, can be used to construct more complex organic molecular structures through various chemical reactions, laying the foundation for the synthesis of organic compounds with special functions.
What are the physical properties of 2-Phenylquinoline?
2-Phenylquinoline is a kind of organic compound. It has unique physical properties, which are described in detail by you.
First of all, its appearance, 2-phenylquinoline is often in a crystalline state, with a pure texture and a certain luster. The formation of this crystalline form is derived from the ordered structure formed by the interaction of its molecules.
As for the melting point, it is about [specific melting point value] degrees Celsius. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point value of 2-phenylquinoline reflects the strength of its intermolecular forces. At this temperature, the molecule is energized enough to break free from the shackles of the solid lattice and begin to flow in the liquid state. The boiling point of
is about [specific boiling point value] degrees Celsius. The boiling point characterizes the conditions for the transformation of substances between liquid and gas states. At this temperature, the surface and interior of the liquid simultaneously vaporize violently, and the molecules escape from the liquid phase to form a gas phase.
In terms of solubility, 2-phenylquinoline has a certain solubility in organic solvents such as ethanol and chloroform. This is because the organic solvent and 2-phenylquinoline molecules can form interactions such as van der Waals force and hydrogen bonds, which help them disperse in the solvent. However, in water, its solubility is very small, because the polarity of water and the molecular structure of 2-phenylquinoline are quite different, and the interaction between the two is difficult to overcome the molecular cohesion of 2-phenylquinoline.
Density is also one of its important physical properties, which is about [specific density value] g/cm3. Density reflects the mass per unit volume of a substance, reflecting the close arrangement of molecules and the relative mass size.
In addition, 2-phenylquinoline is relatively stable under normal temperature and pressure. In case of specific conditions, such as high temperature, strong oxidants or catalysts, it can also participate in many chemical reactions, demonstrating its reactivity as an organic compound.
The above are all the physical properties of 2-phenylquinoline, which will help you gain a deeper understanding of this compound.
Is 2-Phenylquinoline chemically stable?
2-Phenylquinoline is also an organic compound. The stability of its chemical properties depends on various factors and cannot be generalized.
In terms of structure, the quinoline ring is connected to the phenyl group to form a unique conjugated system. This conjugated structure makes the molecular electron cloud more uniform and gives a certain stability. The π electrons of the aromatic ring are delocalized, which reduces the energy of the system and stabilizes the structure.
However, the stability is not static. In case of strong oxidants, such as potassium permanganate, some groups on the quinoline ring or phenyl group can be oxidized. Although the aromatic ring is relatively stable, under strong oxidation conditions, oxidation reactions may still occur, resulting in structural changes. < Br >
In the case of electrophilic reagents, due to the difference in electron cloud density distribution between quinoline ring and phenyl group, electrophilic substitution reactions are prone to occur in areas with higher electron cloud density. Although the overall structure is stable, under the attack of electrophilic reagents, it can also initiate reactions and change chemical properties.
Re-discussion on the influence of temperature and environment. At high temperatures, the thermal motion of molecules intensifies, the vibration of chemical bonds is enhanced, and the stability may be challenged. In acid-base environments, if 2-phenylquinoline has reactive groups, it will also react due to acid-base catalysis, which affects its stability.
The stability of 2-phenylquinoline is not absolute, and its chemical properties can be changed under specific conditions. It is necessary to comprehensively consider factors such as structure, reagents, temperature, and environment in order to understand the full picture of its stability.
What are the synthesis methods of 2-Phenylquinoline?
2-Phenylquinoline is an organic compound, and its synthesis method has been explored by many scholars in the past. It is briefly described as follows:
First, aniline and acetophenone are used as raw materials, and can be obtained through the steps of condensation and cyclization. First, aniline and acetophenone are condensed under the action of an appropriate catalyst to form an intermediate product. The catalyst used is either a protonic acid or a Lewis acid, depending on the reaction conditions and yield. The condensation product is then cyclized to form the structure of 2-phenylquinoline. This cyclization process may require heating or the addition of an agent to promote cyclization before the reaction can proceed smoothly. < Br >
Second, o-aminobenzaldehyde and styrene derivatives are used as starting materials. O-aminobenzaldehyde and styrene derivatives undergo the process of addition and intramolecular cyclization under a specific reaction environment. In this addition reaction, transition metal catalysts are often required to promote the activity and selectivity of the reaction. The addition product undergoes intramolecular cyclization under appropriate conditions to form the structure of 2-phenylquinoline. This approach can regulate the substituents of the product due to the characteristics of the starting materials and enrich the structural diversity of the product.
Third, the coupling reaction catalyzed by transition metals. Using haloquinoline and phenylboronic acid or its derivatives as raw materials, Suzuki coupling reaction or other similar coupling reactions occur under the catalysis of transition metals (such as palladium, copper, etc.). In the reaction, the transition metal catalyst and the ligand work synergistically to activate haloquinoline and phenylboronic acid, so that they are coupled to form 2-phenylquinoline. This method has relatively mild conditions and good compatibility with functional groups, so it is widely used in organic synthesis.
All synthesis methods have their own advantages and disadvantages, or the raw materials are easy to obtain and the steps are complicated, or the conditions are harsh but the yield is high. Experimenters should carefully choose suitable methods according to their own needs, availability of raw materials and experimental conditions, in order to achieve the purpose of synthesizing 2-phenylquinoline.
What is the price range of 2-Phenylquinoline in the market?
In today's market, the price of 2-phenylquinoline is difficult to determine. The price of phenylquinoline often varies due to various reasons, such as the place of production, the quality of the coarse, and the demand for supply.
Looking back at the past, the price of materials sold in the city varied depending on the place of origin. If the place of production is abundant, the quantity produced is large, the price may be slightly lower; if the place of origin is remote, difficult to harvest and transport, and the quantity is small and there are many people seeking, the price will be high. 2-Phenylquinoline is the same. Those with a wide area of origin and high production capacity may be priced more easily; those with a narrow area and difficult to obtain will be more expensive.
In addition, the quality of 2-phenylquinoline has a great impact on the price. Refined 2-phenylquinoline has few impurities and high purity. It is convenient for all kinds of things, and its price is high. If the quality is not pure and contains more impurities, although it can be used for ordinary things, the price must be lower than that of the refined one.
Furthermore, the state of demand is the main reason for pricing. If there are many people who need 2-phenylquinoline in the world, and there are few people who supply it, the merchant will take advantage of the time to raise the price to seek a big profit; on the contrary, if the market is full of this product and there are few people who want it, the merchant will sell it quickly, or reduce the price to get rid of it. < Br >
Therefore, in order to know the exact price of 2-phenylquinoline, it is necessary to consult the merchants of the city, carefully check the current demand for supply, and review the real estate office in order to obtain a more accurate price, rather than a range of prices that can be determined.