2-oxo-1,2-dihydroquinoline-4-carboxylate

2-Oxo-1,2-dihydroquinoline-4-carboxylate is one of the organic compounds and is useful in many fields.
In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to the common structure of quinoline in many bioactive molecules, 2-oxo-1,2-dihydroquinoline-4-carboxylate can be chemically modified to access various functional groups to develop compounds with specific pharmacological activities. For example, for some disease-related targets, drugs synthesized from this intermediate are expected to exhibit good therapeutic effects, such as anti-tumor, antibacterial, anti-inflammatory, etc. < Br >
In the field of materials science, it also has potential applications. Some organic compounds can exhibit unique photoelectric properties after specific design and synthesis. 2-Oxo-1,2-dihydroquinoline-4-carboxylate may be used to prepare materials with specific photoelectric properties through reasonable molecular design, such as in organic Light Emitting Diode (OLED), solar cells and other devices, providing new ways for material performance optimization.
Furthermore, in the field of organic synthesis chemistry, as an important intermediate, it can participate in a variety of chemical reactions to construct more complex organic molecular structures. With different reaction conditions and reagents, it can undergo functional group transformation, cyclization and other reactions, thereby enriching the structural diversity of organic compounds and contributing to the development of organic synthetic chemistry.
In summary, 2-oxo-1,2-dihydroquinoline-4-carboxylate plays an important role in many fields such as medicine, materials and organic synthesis, and has broad application prospects and research value.

2-Oxo-1,2-dihydroquinoline-4-carboxylate is a type of organic compound. Its physical properties are crucial to the behavior of this compound in various environments and reactions.
When it comes to appearance, this compound is often a crystalline solid, with a color ranging from white to pale yellow. The crystalline morphology implies that its molecules are arranged in a regular order in the solid state, and this arrangement affects many of its properties. Its melting point is a specific value, which is crucial for the identification and purification of this compound. Knowing the melting point allows chemists to judge the purity of the compound, as impurities usually widen or decrease the melting point range.
In terms of solubility, 2-oxo-1,2-dihydroquinoline-4-carboxylate exhibits specific solubility properties in organic solvents. In polar organic solvents such as ethanol and acetone, there may be a certain solubility, because some groups in the molecular structure can form interactions with solvent molecules, such as hydrogen bonds or dipole-dipole interactions. However, in non-polar solvents such as n-hexane, the solubility may be very low, because the molecules are not highly non-polar.
The density of this compound is also an important physical property. The density determines its floating or sinking in liquid mixtures, and this property needs to be taken into account in processes involving liquid-liquid separation or mixing.
Furthermore, the stability of 2-oxo-1,2-dihydroquinoline-4-carboxylate to light and heat is also a physical property category. If it is sensitive to light, it may decompose or undergo chemical reactions under light, resulting in changes in its structure and properties. Similarly, when the thermal stability is poor, it is easy to decompose or rearrange under heat, limiting its application in high temperature environments.
In addition, its refractive index is also a physical property. The refractive index reflects the degree of bending of light when passing through this compound, which may be of some significance in applications related to optical materials or analytical techniques. The physical properties of 2-oxo-1,2-dihydroquinoline-4-carboxylate are diverse, ranging from appearance, melting point, solubility to density, stability, and refractive index, all of which play a key role in their research and application in chemistry, materials science, and related fields.

To prepare 2-oxo-1,2-dihydroquinoline-4-carboxylate, follow the ancient method as follows:
First take an appropriate amount of anthranilic acid, place it in the kettle, and use alcohol as a solvent, such as ethanol, in an amount sufficient to fully disperse anthranilic acid. Then add an appropriate amount of acetic anhydride, which has a molar ratio of about 1.2:1 to anthranilic acid. After mixing the two, slowly raise the temperature to 60-80 degrees Celsius. This process needs to be carefully observed to make the temperature in the kettle rise smoothly.
After reaching the specified temperature, maintain this temperature and continue to stir for about 2-3 hours (about 3-4.5 hours) to fully react. During the reaction, the material in the kettle gradually changes, the visible color changes, and the smell is slightly different.
After the reaction is completed, the product in the kettle is poured into ice water, and precipitation can be seen at this time. Then filter with a Brinell funnel to collect the precipitation. Then wash it with cold water several times to remove impurities until the filtrate is clear.
The obtained precipitation is recrystallized with an appropriate amount of ethanol. The precipitation is placed in ethanol, heated to dissolve, then slowly cooled to room temperature, and then moved into an ice bath to make the crystallization more perfect. After suction filtration, the crystals are collected and dried at low temperature in an oven to obtain pure 2-oxo-1,2-dihydroquinoline-4-carboxylate.
Throughout the process, it is necessary to strictly abide by the procedures and control the temperature, dosage and time in order to obtain satisfactory products.

2-Oxo-1,2-dihydroquinoline-4-carboxylic acid ester, this substance has a wide range of uses and has extraordinary applications in many fields such as medicine, chemical industry, and materials.
In the field of medicine, it is often a key intermediate in drug synthesis. Through delicate chemical modification and reaction, compounds with specific biological activities can be constructed. In the development of anti-cancer drugs, this is used as a starting material to synthesize drugs that can precisely act on cancer cell targets through a series of reactions, interfering with the proliferation and metastasis of cancer cells, providing a powerful weapon for conquering cancer. In the field of antimicrobial drugs, drugs can be derived that have significant inhibitory effects on specific bacteria and help humans resist the invasion of pathogens.
In the chemical industry, it plays an important role in dye synthesis. Due to its special chemical structure, it can impart excellent color fastness and color brightness to dyes. It is widely used in the textile, printing and dyeing industries to make fabrics look colorful and bright after multiple washes and lighting. It is also used in plastics, rubber and other polymer material additives to improve material stability and weather resistance and prolong service life.
In the field of materials, it can be used to prepare functional materials. In terms of optical materials, it can participate in the synthesis of materials with special optical properties for optoelectronic devices, such as Light Emitting Diode (LED), to optimize luminous efficiency and color purity; in polymer composites, the addition of this substance can improve the mechanical properties of materials, enhance strength and toughness, and meet the high-performance needs of materials in high-end fields such as aerospace and automobile manufacturing.
It can be seen that although 2-oxo-1,2-dihydroquinoline-4-carboxylic acid ester is an organic compound, it plays a key role in many fields with its unique chemical structure and reactivity, contributing to human life and scientific and technological progress.

2-Oxo-1,2-dihydroquinoline-4-carboxylic acid ester, this product has considerable market prospects in the current market. Guanfu Chemical Industry, the field of organic synthesis, is often a key intermediary. In the process of drug creation, many new agents with special curative effects are developed based on it. Due to its unique chemical structure, a variety of bioactive molecules can be derived, which is of great significance for the development of antimalarial, antimicrobial and anti-tumor drugs.
In the field of materials science, 2-oxo-1,2-dihydroquinoline-4-carboxylic acid esters have also emerged. Because it can participate in the synthesis of polymer materials, the material has unique optical and electrical properties, and has great potential for the preparation of optoelectronic materials and high-performance polymers.
Furthermore, with the gradual rise of the concept of green chemistry, the optimization and innovation of its synthesis process has also become a trend. The exploration of efficient and environmentally friendly synthesis paths can reduce production costs, increase production efficiency, and meet the needs of sustainable development. Therefore, this compound is expected to expand the boundaries of application due to the advancement of technology in the future market, and gain wider attention and application. It will occupy an increasingly important position in the chemical industry, medicine, materials and other industries, leading the reform and development of related fields.