2-METHYLQUINOLINE-4-CARBOXALDEHYDE

2-Methylquinoline-4-formaldehyde has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate and participates in the synthesis of many drugs. Due to the unique chemical properties of quinoline and aldehyde groups, it can react with a variety of compounds to build complex medicinal molecules. For example, in the creation of some antibacterial and anti-inflammatory drugs, 2-methylquinoline-4-formaldehyde can be integrated into the core structure of the drug through specific reaction steps to give the drug corresponding biological activity.
In the field of materials science, it also has important uses. It can be used to prepare organic materials with unique functions. Alaldehyde groups can participate in polymerization reactions, etc., and combine with other monomers to shape materials with special photoelectric or mechanical properties. For example, in the research and development of organic Light Emitting Diode (OLED) materials, with the special structure of 2-methylquinoline-4-formaldehyde, luminescent materials with high luminous efficiency and excellent stability can be synthesized to improve the performance of OLED devices.
In addition, in the field of dye chemistry, it is also useful. It can be used as an important raw material for the synthesis of new dyes. The quinoline ring imparts a certain conjugate structure to the dye, which helps to enhance the color depth and stability of the dye. The aldehyde group can introduce different substituents through chemical modification to adjust the affinity and dyeing performance of the dye to different substrates, so as to meet the diverse dyeing needs.

2-Methylquinoline-4-formaldehyde is one of the organic compounds. It has many physical properties and is widely used in the field of chemistry.
Looking at its appearance, 2-methylquinoline-4-formaldehyde is solid or crystalline at room temperature, with a white or yellowish color and fine texture. This appearance characteristic makes it easy to distinguish among many chemical substances.
When it comes to melting point, the melting point of this compound is in a specific range, and this value is an important physical parameter. Due to the existence of melting point, its physical state can be controlled by temperature regulation in chemical experiments and industrial production. For example, in a specific chemical reaction, it is necessary to maintain the temperature above the melting point to make it liquid to facilitate the smooth progress of the reaction; or in the separation and purification of substances, the difference in melting point is used to achieve separation from other substances.
The boiling point is also an important physical property of 2-methylquinoline-4-formaldehyde. The boiling point indicates the temperature at which it changes from liquid to gaseous state under a specific pressure. This property is crucial in separation technologies such as distillation. By precisely controlling the temperature, it reaches its boiling point, vaporizes it, and then separates from other substances with different boiling points to achieve the purpose of purification.
In terms of solubility, 2-methylquinoline-4-formaldehyde exhibits different solubility in various organic solvents. In some polar organic solvents, such as ethanol and acetone, it has good solubility and can be uniformly dispersed to form a solution. This property makes it possible to use a suitable solvent to promote full contact of the reactants, accelerate the reaction rate and improve the reaction efficiency in organic synthesis reactions. However, in water, its solubility is poor, which is determined by the interaction between its molecular structure and water molecules.
In addition, 2-methylquinoline-4-formaldehyde has a certain volatility. Although the volatility is not very significant, some substances will evaporate into the air under open environment or heating conditions. This characteristic should be paid attention to during storage and use. It should be ensured that the storage environment is well sealed and operated in a fume hood to prevent its volatilization from causing losses or adverse effects on the environment and human health.
In summary, the physical properties of 2-methylquinoline-4-formaldehyde, such as appearance, melting point, boiling point, solubility and volatility, are interrelated and jointly determine their application and treatment in the chemical field.

The stability of the chemical properties of 2-methylquinoline-4-formaldehyde is related to many aspects. In terms of structure, the quinoline ring has a certain conjugate system, which makes the molecule relatively stable. The methyl group is connected to the quinoline ring. Due to the effect of the methyl power supply, or the influence on the density distribution of the ring electron cloud, the effect has not greatly shaken the overall structural stability.
Under common conditions, if there are no extreme factors such as strong oxidants and strong acids and bases in the environment, 2-methylquinoline-4-formaldehyde can maintain a certain stability. Although the aldehyde group is active and easily involved in oxidation, addition and other reactions, it will not react rapidly at room temperature and pressure without specific reagents.
However, in case of high temperature, the internal energy of the molecule increases, the activity of chemical bonds is enhanced, or a reaction occurs, which affects its stability. In case of strong oxidants, the aldehyde group is easily oxidized to a carboxyl group; in case of nucleophiles, the aldehyde group may undergo an addition reaction.
Overall, 2-methylquinoline-4-formaldehyde is chemically stable under conventional mild conditions; however, under special and harsh conditions, such as high temperature, strong oxidation or strong nucleophilic environment, its stability will be challenged, or chemical reactions will occur to transform into other substances.

The synthesis methods of 2-methylquinoline-4-formaldehyde have existed in ancient times and are of various kinds. The following are several common approaches:
First, quinoline derivatives are used as starting materials. Under specific conditions, the quinoline ring is modified to introduce methyl and aldehyde groups at the desired position. For example, a suitable quinoline substrate is selected, and when a catalyst is involved, the methyl group is introduced into the 2-position of the quinoline ring by electrophilic substitution reaction. Then, through oxidation or other functional group conversion steps, the aldehyde group is constructed at the 4-position. This process requires fine regulation of reaction conditions, such as temperature, reaction time, catalyst type and dosage, etc., because each factor has a significant impact on the yield and purity of the product.
Second, with the help of heterocyclic synthesis strategy. Starting from the basic organic raw materials, the quinoline ring is constructed by multi-step reaction, and the reaction route is ingeniously designed to make the methyl group and aldehyde group fall precisely at the target position. Although this method is complicated, it can effectively control the structure of the product. For example, using aniline derivatives and β-ketoate as starting materials, through a series of reactions such as condensation and cyclization, the quinoline parent nucleus is first constructed, and then methyl group and aldehyde group are introduced.
Third, a metal-catalyzed coupling reaction is used. Using the unique activity of metal catalysts, specific fragments containing methyl and aldehyde groups are connected to the quinoline ring through coupling reaction. This method has high selectivity and can obtain the target product efficiently. However, metal catalysts are expensive, and the reaction conditions are also harsh, which requires high reaction equipment and operation.
In actual synthesis, it is necessary to weigh and choose the most suitable synthesis method according to many factors such as experimental conditions, availability of raw materials, cost considerations, and product purity requirements, in order to efficiently prepare 2-methylquinoline-4-formaldehyde.

I look at your question, but I am inquiring about the price range of 2-methylquinoline-4-formaldehyde in the market. However, this price is not constant and is made due to various factors.
First, the purity of this compound is extremely critical. If the purity is high, it is close to chemical purity or analytical purity, and its price is high; if the purity is slightly lower, it is used for general experiments, and the price may be slightly reduced.
Second, the purchase quantity also affects the price. If the purchase quantity is small, it is only a single use in the laboratory, and the merchant may price it at retail, and the price is higher; if the purchase quantity reaches a certain quantity, the merchant may offer a discount to promote sales, and the price will decrease.
Third, the market supply and demand situation cannot be ignored. If the demand for this product is strong and the supply is limited, the price will rise; if the supply is sufficient, the demand will slow down slightly, and the price may stabilize or drop.
In addition, the manufacturer and brand also affect its price. Well-known manufacturers, with their excellent craftsmanship and quality assurance, the price may be higher than that of ordinary manufacturers.
In general, if you buy a small amount in the laboratory, if the purity is higher, the price per gram may be in the tens to hundreds of yuan. If you buy in bulk, such as the kilogram level, the price per kilogram may be between several thousand yuan and ten thousand yuan. However, this is only a rough estimate. The actual price needs to be consulted with various chemical raw material suppliers before the exact number can be obtained.