2 Methyl 4 Aminoquinoline
quinoline thiophene imidazole thiazole

2-Methyl-4-aminoquinoline

Taiy Chemical

    Specifications

    HS Code

    794617

    Name 2-Methyl-4-aminoquinoline
    Molecular Formula C10H10N2
    Molecular Weight 158.20 g/mol
    Appearance Solid (usually)
    Physical State At Room Temperature Solid
    Odor Typical organic compound odor
    Melting Point 98 - 100 °C
    Boiling Point 306 - 307 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, chloroform
    Stability Stable under normal conditions
    Hazardous Nature May be harmful if swallowed, inhaled or in contact with skin

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    General Information
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    Frequently Asked Questions

    As a leading 2-Methyl-4-aminoquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-Methyl-4-aminoquinoline?
    2-Methyl-4-aminoquinoline is one of the organic compounds. It has many unique chemical properties and has important uses in many fields.
    First of all, this substance is alkaline. Because its molecular structure contains nitrogen atoms, this nitrogen atom has lone pairs of electrons and can accept protons, so it is alkaline. This alkaline property allows it to react with acids to form corresponding salts. For example, by reacting with hydrochloric acid, 2-methyl-4-aminoquinoline hydrochloride can be obtained. This reaction is actually a process of acid-base neutralization, and the solubility of the generated salts in water is often better than that of the original compound. This property is of great value in the preparation, separation and purification of drugs.
    Secondly, the aromaticity of 2-methyl-4-aminoquinoline is also an important chemical property. Its quinoline ring structure satisfies the Shockell rule and has a high degree of stability. This aromaticity makes its electron cloud distributed uniformly, and its chemical properties are relatively stable. It is not prone to addition reactions, but more prone to electrophilic substitution reactions. For example, under appropriate conditions, halogenation, nitrification, sulfonation and other electrophilic substitution reactions can occur, and corresponding substituents can be introduced into the ring, and then a variety of compounds with different functions can be derived.
    Furthermore, the amino group of the compound is also active. Amino groups can participate in a variety of chemical reactions, such as acylation reactions. When interacting with acyl chloride or acid anhydride, the hydrogen atom on the amino group can be replaced by acyl groups to form amide derivatives. This reaction is often used in organic synthesis to form new chemical bonds to prepare compounds with specific biological activities or physicochemical properties.
    In addition, the methyl group of 2-methyl-4-aminoquinoline is not completely inert. Under some special reaction conditions, methyl groups can undergo oxidation, halogenation and other reactions, providing a possible way for the modification and modification of molecular structures.
    In summary, 2-methyl-4-aminoquinoline shows important application potential in organic synthesis, medicinal chemistry and other fields due to its basic, aromatic, amino and methyl reactive chemical properties. It can be structurally modified and functionalized through various chemical reactions to meet different practical needs.
    2-Methyl-4-aminoquinoline in what areas?
    2-Methyl-4-aminoquinoline, which is useful in many fields such as medicine and chemical industry.
    In the field of medicine, it is an important intermediate for drug synthesis. The preparation of many antimalarial drugs depends on its participation. Malaria is an ancient disease, and it is very harmful. In the past, malaria epidemics were rampant, and people were struggling to live. And antimalarial drugs containing 2-methyl-4-aminoquinoline structure are like a god's weapon, making great contributions to the fight against malaria. Because it can effectively interfere with the metabolic process of malaria parasites, curb their reproduction in human red blood cells, thereby alleviating and even curing malaria and saving thousands of patients from illness.
    In the chemical industry, it is also indispensable. In the synthesis of dyes, it is often used as a key raw material. With its special chemical structure, dyes with colorful and excellent performance can be synthesized. As in the past printing and dyeing workshops, if you want to get bright and long-lasting colors, the dyes made of 2-methyl-4-aminoquinoline are the best choice. Based on it, the dyed fabrics have a bright color and will not fade after being washed over the years, which is deeply loved by everyone. At the same time, in the preparation of some functional materials, 2-methyl-4-aminoquinoline can endow the materials with unique physical and chemical properties, such as improving the optical and electrical properties of the materials, which can help the research and development and application of new materials.
    What is 2-Methyl-4-aminoquinoline synthesis method?
    The synthesis of 2-methyl-4-aminoquinoline is the key to chemical preparation. In the past, the synthesis of this compound often followed various paths.
    First, the quinoline derivative was used as the starting material. First, the appropriate quinoline precursor was taken, and the specific position was modified through fine chemical reactions. If the halogenated quinoline was used as the starting point, under specific conditions, the methylation reaction was carried out with a suitable methylating reagent. In this process, the reaction temperature, time, reagent dosage and other factors need to be precisely controlled. If the temperature is too high or too low, the reaction may deviate from the expected, or form by-products, or the reaction rate is too slow. Uncertain time control will also affect the purity and yield of the product.
    After the methyl group is successfully introduced, the amination step is carried out. Suitable amination reagents are often selected to replace the halogen atom with an amino group in the presence of a catalyst. The type and amount of catalyst have a great impact on the reaction process. Different catalysts have different activities and need to be carefully selected according to the specific reaction system.
    Second, it is also synthesized by the strategy of constructing nitrogen-containing heterocycles. Starting from the basic nitrogen-containing raw materials, the quinoline skeleton is constructed by multi-step cyclization reaction. For example, a specific amine and aldehyde-ketone compounds are first synthesized by condensation reaction in an acidic or basic catalytic environment. This intermediate is then cyclized to form a quinoline ring under the action of a high temperature and highly active catalyst. Then, according to the above method, methyl and amino groups are introduced in sequence.
    When synthesizing 2-methyl-4-aminoquinoline, every step of the reaction is a matter of success or failure. Precise control of reaction conditions, such as pH, temperature, pressure, etc., as well as careful selection of reactants and catalysts, is the key to obtaining high-purity and high-yield products. The separation and purification steps after the reaction should not be underestimated. It is necessary to use re-distillation, extraction, chromatography and other techniques to obtain pure 2-methyl-4-aminoquinoline.
    What is the market outlook for 2-Methyl-4-aminoquinoline?
    2-Methyl-4-aminoquinoline has attracted much attention in the field of pharmaceutical and chemical industry. Looking at its market prospects, it is like the first light of dawn, which is quite vigorous.
    At the end of medicine, it is a key raw material for the synthesis of antimalarial drugs. Malaria is a major infectious disease worldwide, which is very harmful. The chemical structure of 2-methyl-4-aminoquinoline makes it a cornerstone and indispensable in the synthesis of antimalarial drugs. With the increasing attention to malaria prevention and control worldwide, the demand for antimalarial drugs continues to rise. Therefore, the production of related drugs based on this raw material is expected to expand the market and create a broader demand space for 2-methyl-4-aminoquinoline.
    Furthermore, in the chemical industry, it can be used as an intermediate for organic synthesis. The industry of organic synthesis is like the construction of a building, and intermediates are like the pillars in the middle. With its unique chemical properties, 2-methyl-4-aminoquinoline can participate in many organic reactions and derive various high-value-added fine chemicals. With the fine development trend of the chemical industry, the demand for such high-performance intermediates will surely rise.
    However, although the market prospect is bright, there are also challenges. First, the optimization of the synthesis process is a top priority. If the process is complicated and costly, it will hinder its large-scale production and marketing activities. Second, the stricter regulation requires the production process to strictly abide by environmental and safety standards. Although this is a move to regulate the industry, it also makes the production company face higher compliance costs.
    Overall, the 2-methyl-4-aminoquinoline market has a bright future, but it also needs to deal with many challenges. If it can be properly resolved, it will be able to emerge in the market and shine.
    2-Methyl-4-aminoquinoline impact on the environment
    2-Methyl-4-aminoquinoline is a genus of organic compounds. The impact of this on the environment cannot be ignored.
    It may enter the natural environment due to the production of chemical industry, the process of pharmaceutical production, and even the use and disposal of related products.
    In water bodies, if 2-methyl-4-aminoquinoline exists, it may cause water quality to deteriorate. Aquatic organisms live in this environment and suffer first. It may interfere with the physiological functions of aquatic organisms, or damage their respiratory and circulatory systems, cause their movement to be sluggish, or even endanger their lives. For plankton, it may also disturb their growth and reproduction process, and then disrupt the balance of aquatic ecology.
    As for the soil environment, if it penetrates into the soil, it may set up obstacles for the activity of soil microorganisms. Soil microorganisms play a key role in soil fertility maintenance and material circulation. The existence of 2-methyl-4-aminoquinoline, or the structural and functional changes of microbial communities, damage the ecological function of soil.
    In the atmospheric environment, although its volatilization and existence in the air may be rare, it should not be ignored. It may be breathed into organisms, and may have adverse effects on the human respiratory system, nervous system, etc.
    And 2-methyl-4-aminoquinoline has a certain stability, is difficult to degrade in the environment, and is easy to accumulate. Over time, the potential threat to the ecological environment will gradually become apparent, so it should be handled with caution to prevent it from causing serious harm to the environment.