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What is the chemical structure of 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione?
The Chinese name of 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione is 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione. This is an organic compound with complex and unique chemical structure.
The core structure of this compound is benzo [de] isoquinoline, which is formed by fusing a phenyl ring with an isoquinoline ring. At the second position of 1H-benzo [de] isoquinoline, there is a hydroxyl group (-OH) connected. This hydroxyl group has active chemical properties and can participate in various chemical reactions, such as nucleophilic substitution reactions, esterification reactions, etc., which have a great influence on the physical and chemical properties of the compound.
At the 1,3 (2H) position, there are two carbonyl groups (C = O), that is, the dione structure. The presence of carbonyl groups makes the compound have certain polarity and reactivity, and can undergo addition reactions with nucleophiles. This dione structure may also affect the conjugation system of the compound, which in turn affects its optical and electronic properties.
The overall chemical structure of 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione gives it potential application value in organic synthesis, medicinal chemistry and other fields. Due to its particularity of structure, it may be used as a key intermediate in the synthesis of biologically active compounds and play an important role in the development of new drugs.
What are the main uses of 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione?
2-Hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione, which is a unique organic compound, has important uses in many fields.
In the field of medicine, it shows significant potential. Because of its unique structure, it can interact with specific targets in vivo. Or it can be used as a lead compound and ingeniously modified and optimized to develop new drugs. For example, in the development of anti-tumor drugs, its structural characteristics can be used to design drugs that can precisely inhibit tumor cell proliferation and induce tumor cell apoptosis. Or in the development of drugs for neurological diseases, it is expected to provide effective treatment for related diseases by regulating the transmission of neurotransmitters and inhibiting abnormal activity of nerve cells.
In the field of materials science, it also has extraordinary performance. Because of its specific optical and electrical properties, it can be used to prepare functional materials. For example, it can be used as a key component of luminescent materials in organic Light Emitting Diode (OLED) technology to improve its luminous efficiency and color purity, and contribute to the development of display technology. Furthermore, in terms of sensor materials, with the ability to selectively identify specific substances, high-sensitivity and high-selectivity sensors can be constructed for detecting environmental pollutants, biomarkers, etc. < Br >
In the dye industry, its structure gives unique color light and dyeing properties. As the core component of new dyes, dyes with high color fastness, good light resistance and washable properties can be developed, which are widely used in textile, leather and other industries, bringing new changes to dyeing processes.
In summary, 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione has significant uses in the fields of medicine, materials, dyes, etc. It is a compound with great research value and application prospects.
What are the physical properties of 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione?
2-Hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione is an organic compound. Its physical properties are quite elusive.
When it comes to appearance, this compound is often in a solid state, but its specific color varies according to the preparation method and purity. It is either white to light yellow powder, or in a crystalline form, with a fine and regular texture. It has a specific crystal structure, which is closely related to the interaction between molecules.
As for the melting point, this is one of its important physical properties. After experimental investigation, its melting point is within a certain temperature range, which is crucial for the identification and identification of this compound, and can be used as one of the indicators to measure its purity. The higher the purity, the narrower the range of melting point and the closer to the theoretical value.
In terms of solubility, in common organic solvents, their solubility varies. In some polar organic solvents, such as ethanol and acetone, or with a certain solubility, a uniform solution can be formed. This is because the polar groups contained in the molecular structure can form specific interactions with the solvent molecules, such as hydrogen bonds, van der Waals forces, etc., to promote dissolution. In non-polar solvents, such as n-hexane and toluene, its solubility is very small. Due to the difference between molecular polarity and non-polar solvents, it is difficult to overcome the force between molecules to achieve dissolution.
In addition, density is also a characterization of its physical properties. Although the exact density value needs to be determined by precise experiments, the density is closely related to the mass of the molecule and the degree of molecular packing. The molecular structure of tight packing often corresponds to higher density values.
The physical properties of this compound provide an important basis for its application in chemical synthesis, drug development and other fields. In practical applications, appropriate separation, purification and preparation methods can be selected according to their physical properties to achieve the desired effect.
What are the synthesis methods of 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione?
2-Hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione, that is, 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione. The synthesis method of this compound has been investigated in the past. The common method described above is as follows.
One is to use phthalic anhydride and anthranilic acid as starting materials. Under suitable reaction conditions, the two first undergo a condensation reaction to obtain an intermediate product. This reaction requires a specific catalyst to interact with the temperature and pressure environment, so that the active checking points of the two interact and bond between molecules. Subsequently, the intermediate product is further reacted, or through cyclization, oxidation and other steps, after several fine adjustments, the final product is 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione. In this process, the control of the reaction conditions is extremely critical, the temperature is slightly different, or the reaction rate and product purity are affected; the choice of catalyst is also related to the smooth progress of the reaction, and has a significant effect on the product yield.
The second is based on a specific organic synthesis route, with compounds containing benzene rings and nitrogen heterocycles as starting materials. The functional group of the starting material is modified and activated first, and the skeleton of the target molecule is gradually constructed by classical organic reactions such as nucleophilic substitution and electrophilic addition. During this period, the protective group strategy needs to be skillfully used to avoid unnecessary side reactions and ensure that the reaction is accurately in the direction of generating the target product. After the skeleton is built, the molecular structure is finely carved through subsequent steps such as deprotection and oxidation to finally obtain the product. This synthesis method requires in-depth understanding of the organic reaction mechanism, and the conditions of each step of the reaction need to be carefully designed to achieve higher yield and purity.
The third is to use natural products or compounds with similar structures as raw materials for semi-synthesis. After analyzing the structure of natural products, finding their modifiable check points, and gradually introducing the required functional groups by means of chemical transformation, the transformation to 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione is realized. This approach often benefits from the inherent structural characteristics of natural products, or can simplify some synthesis steps, but also faces challenges such as limited raw material sources and difficulties in extraction and separation. It is necessary to comprehensively consider its feasibility and economy.
What are the precautions for using 2-hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione?
2-Hydroxy-1H-benz [de] isoquinoline-1,3 (2H) -dione is 2-hydroxy-1H-benzo [de] isoquinoline-1,3 (2H) -dione. When using this compound, pay attention to many matters.
First, safety protection is essential. This compound may be toxic and irritating. When contacting, be sure to wear suitable protective equipment, such as gloves, goggles and protective clothing, to prevent skin and eye contact. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment as appropriate.
Second, the operating environment should be treated with caution. It should be operated in a well-ventilated place. It is best to carry out relevant work in a fume hood to avoid inhaling its dust or volatile gases. If used in a confined space, the gas will accumulate or cause respiratory irritation, and even more serious health problems.
Third, storage conditions should not be ignored. It should be stored in a cool, dry and ventilated place, away from fire and heat sources to prevent deterioration or other safety hazards due to temperature and humidity discomfort. At the same time, it should be stored separately from oxidants, acids, bases, etc., to prevent chemical reactions.
Fourth, the dosage should be strictly controlled during use. Precisely weigh it according to experimental or production needs to avoid waste and prevent uncontrollable reactions or adverse consequences caused by excessive use. After use, properly dispose of the remaining materials, follow relevant environmental protection regulations, and do not discard them at will.
Fifth, understanding its chemical properties is crucial for correct use. Knowing its stability, solubility and possible chemical reactions under different conditions can make reasonable planning steps during use to ensure operation safety and smooth progress of experiments and production.