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What is the main use of 2- [ (diethoxyphosphoryl) oxy] -1H-benzo [de] isoquinoline-1,3 (2H) -dione
2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione is an organic compound with a wide range of common uses. This compound has shown a unique role in the field of pharmaceutical research and development. Due to its specific chemical structure and properties, it may be used as a potential pharmaceutical active ingredient to explore new drugs and treat related diseases.
In the field of materials science, it also has a place. Its special molecular structure may give novel properties to materials. For example, when synthesizing special polymer materials, the introduction of the compound may change the physical and chemical properties of the material, making it special in fields such as optical and electrical materials.
In addition, in agricultural chemistry, 2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione also has potential uses. It may be used as a key component of pesticides or plant growth regulators to help agricultural production and achieve goals such as crop yield increase and pest control. By precisely regulating its chemical properties and mechanism of action, it is expected to develop high-efficiency, low-toxicity and environmentally friendly agricultural chemicals.
In summary, 2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione has shown broad application prospects in many fields such as medicine, materials science and agricultural chemistry, and is worthy of in-depth exploration and development.
What are the physical properties of 2- [ (diethoxyphosphoryl) oxy] -1H-benzo [de] isoquinoline-1,3 (2H) -dione
2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione, this is an organic compound with unique physical properties.
Looking at its shape, under normal temperature and pressure, it is mostly in the shape of a solid state. Its texture may be a crystalline solid, and its appearance may be shiny, like fine crystal jade, crystal clear and clear. Under light, there may be a slight flicker.
Talking about the melting point, it has been determined by many experiments that the melting point of this compound is in a specific temperature range. However, due to subtle differences in experimental conditions, the melting point may fluctuate slightly. Between [X] ° C and [X] ° C, when heated to this temperature range, its lattice structure gradually disintegrates, and the intermolecular force weakens, so it melts from a solid state to a liquid state, just like ice melts when it is warm.
Its solubility is quite critical. In organic solvents, such as common ethanol and acetone, the compound exhibits a certain solubility. In ethanol, under appropriate temperature and stirring conditions, it can partially dissolve to form a uniform solution, just like salt dissolves in water, and the molecules are evenly dispersed. In water, its solubility is poor. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules. Therefore, it is mostly suspended in water in the form of solid particles, like sand particles entering water, and it is difficult to blend with water.
Furthermore, the density of this compound is also fixed. Compared with water, its density may be slightly larger. If it is placed in water, it will slowly sink, like a stone sinking to the bottom, following the law of physical sedimentation.
Its stability is also one of the important physical properties. Under normal environmental conditions, in a dry and dark place, this compound can maintain a relatively stable structure and properties, and is not easy to undergo chemical reactions and deteriorate by itself. However, under extreme conditions such as high temperature, high humidity or strong light, its structure may change and its stability will be damaged, just like a delicate flower in a bad climate, it is easy to lose its true color.
Is 2- [ (diethoxyphosphoryl) oxy] -1H-benzo [de] isoquinoline-1,3 (2H) -dione chemically stable?
2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione, this is an organic compound. Looking at its chemical structure, it contains phosphoryl oxy groups and structural fragments of benzoisoquinoline dione.
In terms of the stability of its chemical properties, many factors need to be considered. From a structural point of view, the part of benzoisoquinoline dione has a conjugated system, and the conjugation effect can improve the molecular stability. The delocalization of π electrons in the aromatic ring reduces the energy of the system and enhances the molecular stability.
And the phosphoryl oxy part, the P-O bond has a certain polarity. The ethoxy group attached to the phosphorus atom can affect the overall properties of the molecule through induction and conjugation effects. The ethoxy group is the power supply subgroup, and the electron cloud density of the phosphorus atom increases through induction effects. This structural characteristic may affect the reactivity of the compound to nucleophiles or electrophiles.
Under common conditions, the compound should be relatively stable if there are no extreme conditions such as strong oxidizing agents, strong reducing agents, strong acids or strong bases in the environment. However, its stability may be affected or affected when high temperatures, high humidity or the presence of specific catalysts. For example, in a strong acid environment, the ester bonds of phosphoryl groups may undergo hydrolysis reactions, resulting in changes in the molecular structure. Under strong alkali conditions, it may also trigger the breaking or rearrangement of certain chemical bonds within the molecule.
In addition, lighting conditions may play a role in its stability. If the molecule absorbs photons of a specific wavelength, or induces electron transitions, it initiates photochemical reactions, which affect its stability.
In general, 2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione have certain stability under normal mild conditions, but under the influence of specific extreme conditions or special environmental factors, its chemical properties are stable or change.
What is the synthesis method of 2- [ (diethoxyphosphoryl) oxy] -1H-benzo [de] isoquinoline-1,3 (2H) -dione
To prepare 2 - [ (diethoxyphosphoryl) oxy] -1H - benzo [de] isoquinoline - 1,3 (2H) - dione, you can do it according to the following method.
First take a certain amount of 1H - benzo [de] isoquinoline - 1,3 (2H) - dione and place it in a suitable reaction vessel. Add an appropriate amount of organic solvent, such as dichloromethane, N, N - dimethylformamide, etc., stir to fully dissolve it to form a uniform solution. < Br >
Take another diethoxyphosphoryl chloride and slowly add it dropwise to the above solution. The dropwise rate should be moderate, and at the same time, a certain reaction temperature should be maintained. Generally, it can be controlled between 0 and 50 ° C. It can be adjusted appropriately according to the actual process and effect of the reaction. Continue to stir during the dropwise addition process to make the reactants fully contact and react.
In order to promote the reaction, an appropriate amount of alkali can be added, such as triethylamine, pyridine, etc. The amount of alkali needs to be accurately calculated and tested to achieve the best reaction effect. During the reaction, the reaction process can be monitored by means of thin-layer chromatography (TLC). When the raw material point is basically eliminated, it indicates that the reaction is approaching completion. After the
reaction is completed, the reaction mixture is post-treated. First, an appropriate amount of water is washed to remove unreacted alkali and some water-soluble impurities, and the organic phase is collected after stratification. Then the organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove the moisture. Subsequently, the organic solvent is removed by vacuum distillation to obtain a crude product.
The crude product can be purified by column chromatography with a suitable eluent, collect the eluent containing the target product, and steam off the solvent to obtain a pure 2- [ (diethoxyphosphoryl) oxy] -1H -benzo [de] isoquinoline-1,3 (2H) -dione product. The whole synthesis process requires strict control of the reaction conditions and operation details of each step to ensure the purity and yield of the product.
2- [ (diethoxyphosphoryl) oxy] -1H-benzo [de] isoquinoline-1,3 (2H) -dione What are the latent risks
2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione is an organic compound, and its related risk of dissolution, let me tell you in detail.
This compound may have different dissolution behaviors in common organic solvents due to the phosphoxy group in its structure. In non-polar organic solvents, such as n-hexane and cyclohexane, because of the large difference between molecular polarity and non-polar solvents, the interaction force is weak, so it is difficult to dissolve, just like oil and water, incompatible with each other.
In polar organic solvents, such as ethanol, acetone, etc., or show a certain solubility. In ethanol, the hydroxyl group can form a hydrogen bond with the polar part of the compound, enhancing the interaction between the two and promoting dissolution; the carbonyl group of acetone can also interact with the compound to produce a dipole-dipole interaction, which is beneficial to dissolve. However, its solubility is not infinite. When it reaches a certain concentration, it will reach a dissolution equilibrium.
In water, this compound may have poor solubility due to the relatively large molecular structure and hydrophobic part. Even if it contains some polar groups, the whole is still biased towards hydrophobicity, just like a difficult-to-dissolve wax, which is difficult to disperse and dissolve in water.
Furthermore, temperature also affects its solubility. Generally speaking, when the temperature increases, the thermal movement of molecules intensifies, and the diffusion speed in the solvent accelerates, which is beneficial for dissolution. However, it also depends on the stability of the compound. If the temperature is too high to cause its decomposition, it is another matter.
In summary, 2-%5B%28diethoxyphosphoryl%29oxy%5D-1H-benzo%5Bde%5Disoquinoline-1%2C3%282H%29-dione non-polar solvents are insoluble, polar organic solvents have a certain solubility, poor solubility in water, and temperature also plays a role in their dissolution process.