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What is the chemical structure of 2-butoxy-n- (2- (diethylamino) ethyl) -4-quinolinecarboxamidmonohydrochlorid?
2-Butoxy - n - (2 - (diethylamino) ethyl) - 4 - quinolinecarboxamidmonohydrochlorid, this is the name of an organic compound. To explain its chemical structure in the style of the ancient proverbs of "Tiangong Kaiwu", when as follows.
The name of this compound, "2-butoxy", is in the second position of the main structure, connected with butoxy. The butoxy group is formed by connecting butyl (a chain-like alkyl group containing four carbons) with an oxygen group. It is shaped like a branch and is attached to a specific position of the main structure. < Br >
"n- (2- (diethylamino) ethyl) ", which means that the nitrogen atom (n) is connected to a group, which is 2- (diethylamino) ethyl. Diethylamino, which is connected by a nitrogen atom to two ethyl groups, ethyl is a chain alkyl group containing two carbons. This 2- (diethylamino) ethyl group is connected to the nitrogen atom of the main structure at one end, as if it were extended by an arm, and is connected to the main structure.
"4 - quinolinecarboxamid", which indicates that the main structure is quinoline, and at the fourth position of quinoline, there is a formamide group. Quinoline, with the ring structure of azonaphthalene, is the core structure of this compound, like the backbone of the house. Formamide is connected to the quinoline 4 position, adding a special functional group to the structure.
Finally "monohydrochlorid" indicates that this compound is a monohydrochloride, that is, the whole compound is combined with a molecule of hydrogen chloride. The hydrogen atom of hydrogen chloride is connected to a specific atom in the compound by a certain chemical action, giving this compound its unique chemical properties.
In summary, this compound takes quinoline as the core, is connected to butoxy group at 2 position, formamide group at 4 position, nitrogen atom and 2 - (diethylamino) ethyl group, and the whole is in the form of monohydrochloride salt, and the parts are connected to each other to form a complex and ordered chemical structure.
What are the main uses of 2-butoxy-n- (2- (diethylamino) ethyl) -4-quinolinecarboxamidmonohydrochlorid?
2-Butoxy-N- (2- (diethylamino) ethyl) -4-quinolinoformamide monohydrochloride, this is an organic compound. Its main uses are quite extensive and of great significance in the field of medicine.
In the process of drug development, it is often used as a key intermediate. It can be skillfully converted into drugs with unique pharmacological activities through specific chemical reactions. Due to its unique molecular structure, it can precisely combine with specific targets in organisms, just like the fit between a key and a keyhole, and then exhibit a variety of biological activities. Or it can regulate specific physiological processes in organisms and greatly assist in the treatment of diseases.
For example, this compound plays an important role in the development of some antimalarial drugs. Malaria is a disease that seriously threatens human health, and with its unique chemical structure, it can effectively inhibit the growth and reproduction of malaria parasites. It is like a sharp blade on the battlefield, precisely attacking malaria parasites and opening up new paths for malaria treatment.
In addition, it has also emerged in the research of drugs related to neurological diseases. Neurological diseases are complex and difficult to treat, and it may regulate the release and transmission of neurotransmitters by interacting with specific receptors on the surface of nerve cells, just like a fine tuner, adjusting the "melody" of the nervous system, providing possible directions for the treatment of neurological diseases such as Alzheimer's disease and Parkinson's disease.
At the same time, in the field of antimicrobial drug research and development, it also has potential to be tapped. It can interfere with the normal physiological metabolism of bacteria, just like destroying the enemy's logistics supply, making it difficult for bacteria to survive and multiply, laying the foundation for the birth of new antimicrobial drugs. In short, 2-butoxy-N - (2 - (diethylamino) ethyl) - 4 - quinoline formamide monohydrochloride has important uses in many directions of pharmaceutical research and development, just like a key to open the door to the treasure house of medicine.
What are the physical properties of 2-butoxy-n- (2- (diethylamino) ethyl) -4-quinolinecarboxamidmonohydrochlorid?
2-Butoxy-N- (2- (diethylamino) ethyl) -4-quinolinoformamide monohydrochloride, this is an organic compound. Its physical properties are rich and diverse, let me tell them one by one.
Looking at its properties, under normal temperature and pressure, it is often in the state of white to quasi-white crystalline powder, which is easy to store and use.
As for solubility, this substance exhibits different degrees of solubility in common solvents such as water and ethanol. In water, it has a certain solubility due to the interaction of polar groups and water molecules in its molecular structure, but it is also restricted by factors such as temperature. When heating up, the solubility may increase, just like the ancients said "hot dissolves, cold condenses". The change of temperature affects the movement of molecules, and then the degree of solubility is left and right. In organic solvents such as ethanol, the solubility is better due to the principle of similar phase dissolution. Because its molecular structure has a certain degree of compatibility with ethanol, the two can be better miscible.
Its melting point is also an important physical property. After determination, the melting point is in a specific temperature range, which provides a key basis for the identification and purification of this compound. Just like the ancient people purified gold and stone, they needed to know its melting point and temperature in order to store it. The determination of the melting point can help distinguish its purity. If it contains impurities, the melting point may be offset.
In addition, the density of the compound also has a specific value under relevant conditions. Density reflects the compactness of a substance and is related to molecular accumulation and structure. This value is of great significance for its distribution and mixing in different media. For example, when preparing a drug, density affects the uniformity of the composition.
In summary, the physical properties of 2-butoxy-N- (2- (diethylamino) ethyl) -4-quinolinoformamide monohydrochloride, such as properties, solubility, melting point, density, etc., are crucial to its research and application, and are indispensable factors in the fields of chemical industry and medicine.
What is the production method of 2-butoxy-n- (2- (diethylamino) ethyl) -4-quinolinecarboxamidmonohydrochlorid?
To prepare 2 - butoxy - n - (2 - (diethylamino) ethyl) - 4 - quinolinecarboxamidmonohydrochlorid, follow the following ancient method.
First take an appropriate amount of 4 - quinolinecarboxylic acid and place it in a clean reactor. Use an alcohol solvent such as ethanol as a medium, add an appropriate amount of 2 - (diethylamino) ethanol, and then add a little concentrated sulfuric acid as a catalyst. Warm to a moderate temperature, about 80 - 90 degrees Celsius, to fully react. The purpose of this step is to esterify 4-quinolinecarboxylic acid with 2 - (diethylamino) ethanol to form n - (2 - (diethylamino) ethyl) - 4 - quinolinecarboxamide. During the reaction, continuous stirring is required to ensure full contact of the reactants and accelerate the reaction process.
After the esterification reaction is completed, cool the reaction solution to room temperature. Take another appropriate amount of 2-butoxy chloride and slowly add it dropwise to the above reaction solution. At the same time, add an appropriate amount of acid binding agent, such as potassium carbonate, to neutralize the hydrogen chloride generated by the reaction. The reaction temperature is maintained at 40-50 degrees Celsius, and the substitution reaction is carried out to introduce the 2-butoxy group into the compound to generate 2-butoxy-n- (2 - (diethylamino) ethyl) - 4 - quinolinecarboxamide.
Finally, the resulting product is dissolved in a suitable organic solvent, such as dichloromethane. Dry hydrogen chloride gas is introduced into it until the product is completely converted to 2-butoxy-n- (2 - (diethylamino) ethyl) - 4 - quinolinecarboxamidmonohydrochlorid. After that, the organic solvent is removed by reduced pressure distillation and recrystallized with a suitable solvent to obtain a purified target product. During the whole process, attention should be paid to the control of temperature, reactant ratio and reaction time to ensure the smooth progress of the reaction and improve the purity and yield of the product.
What are the precautions for the use of 2-butoxy-n- (2- (diethylamino) ethyl) -4-quinolinecarboxamidmonohydrochlorid?
2-butoxy-N - (2 - (diethylamino) ethyl) -4 -quinoline formamide monohydrochloride, this is a rather complex chemical agent. During use, many matters need to be paid attention to.
Bearing the brunt, it is necessary to read and strictly abide by the instruction manual attached to the drug. This instruction manual is like a "drug" guide, which contains detailed key information on the usage, dosage, applicable conditions, and contraindications of the drug. Do not increase or decrease the dose without authorization. If the dosage is too small, it may not achieve the expected efficacy; if the dosage is too much, it is easy to cause adverse reactions and damage the body.
Furthermore, the user must pay attention to his own physical condition. During the medication period, if you feel sudden discomfort, such as rash, itching, breathing difficulties and other allergic symptoms, or have adverse reactions such as dizziness, nausea, vomiting, etc., you should stop the medication immediately and seek medical treatment as soon as possible. Due to individual physical differences, the reaction to the drug varies, so it is essential to pay close attention to your own reaction.
Storage should not be underestimated. It should be properly stored according to the storage conditions required by the drug, or at room temperature, or refrigerated, and avoid exposure to high temperature, humidity or direct sunlight. Improper storage can easily cause the drug to deteriorate and impair its efficacy.
At the same time, when using this drug, you should also pay attention to its interaction with other drugs. If you are taking other drugs, you should inform your doctor or pharmacist to prevent the drugs from interfering with each other and causing adverse consequences.
In addition, special groups, such as pregnant women, breastfeeding women, children, the elderly and people with hepatic and renal insufficiency, need to be cautious with medication. The physical functions of such people are different from ordinary people, and the impact of drugs on them may be more complicated. Therefore, it is necessary to consult a professional doctor before use, and obtain their guidance before taking medication.
In short, when using 2-butoxy-N - (2 - (diethylamino) ethyl) -4 -quinolinoformamide monohydrochloride, all aspects should not be ignored, so as to ensure the safety and effectiveness of medication.