2 Benzylthio Quinoline
quinoline thiophene imidazole thiazole

2-(Benzylthio)quinoline

Taiy Chemical

    Specifications

    HS Code

    967541

    Chemical Formula C16H13NS
    Molar Mass 251.346 g/mol
    Appearance Solid (usually)
    Physical State At Room Temperature Solid
    Melting Point Data specific to compound needed
    Boiling Point Data specific to compound needed
    Solubility In Water Low (organic compound, likely hydrophobic)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Odor Likely has a characteristic organic odor
    Color Color may vary, often pale - colored solid

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    General Information
    Where to Buy 2-(Benzylthio)quinoline in China?
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    Frequently Asked Questions

    As a leading 2-(Benzylthio)quinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (Benzylthio) quinoline?
    2-%28Benzylthio%29quinoline is 2- (benzythio) quinoline, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, Gai can derive many organic compounds with specific functions and structures through various chemical reactions, such as participating in the construction of complex heterocyclic systems, laying the foundation for the synthesis of new drugs, natural products and functional materials.
    In the field of medicinal chemistry, 2- (benzythio) quinoline shows potential biological activity. Studies have shown that some compounds containing this structure have pharmacological properties such as antibacterial, anti-inflammatory and anti-tumor. It can be used as a lead compound, and innovative drugs with better efficacy and less side effects can be developed through structural modification and optimization.
    In the field of materials science, 2- (benzylthio) quinoline is also used. Due to its unique electronic structure and chemical properties, it can be used to prepare photoelectric materials, such as organic Light Emitting Diodes (OLEDs), solar cells, etc., to improve the photoelectric properties of materials.
    In addition, in analytical chemistry, its special structure and properties can be used as analytical reagents for qualitative or quantitative analysis of certain substances, helping to detect and identify specific compounds.
    What are the physical properties of 2- (Benzylthio) quinoline?
    2-%28Benzylthio%29quinoline, the Chinese name 2- (benzythio) quinoline, is a kind of organic compound. Its physical properties are as follows:
    In terms of view, this substance is usually in a solid state, and the color may be white to light yellow. Its melting point is about [specific value], and the melting point can be determined by conventional means such as capillary method. The characteristics of the melting point are related to its purity and intermolecular forces, which have an important impact on its physical state under specific conditions.
    As for solubility, 2- (benzythio) quinoline has a certain solubility in organic solvents such as ethanol and dichloromethane, but its solubility in water is very small. This difference in solubility is due to the role of hydrophobic groups in its molecular structure. The molecules of organic solvents and the intermolecular forces of the compound are more conducive to its dissolution than water molecules.
    Furthermore, its boiling point is also a key physical property. Under normal pressure, the boiling point is about [specific value]. The boiling point reflects the energy required for a compound to transform from a liquid state to a gas state, which is restricted by factors such as the attractive force between molecules and the relative molecular mass.
    In addition, the density of 2- (benzythio) quinoline also has a specific value, which is about [specific value] g/cm ³. The density is the mass of the substance per unit volume, and this value is of great significance for the consideration of mixing and separation operations in practical applications.
    Its refractive index is also one of the parameters that characterize the physical properties, which is about [specific value]. The refractive index reflects the degree of change in the direction of light propagation in the substance, and is related to the molecular arrangement and electron cloud distribution of the substance. It is quite useful for identification and purity analysis.
    In summary, the physical properties of 2- (benzythio) quinoline, such as melting point, solubility, boiling point, density and refractive index, play an important guiding role in its application in many fields such as organic synthesis and materials science. Researchers can choose appropriate methods according to their physical properties to process, separate and apply them.
    What are the chemical properties of 2- (Benzylthio) quinoline?
    2-%28Benzylthio%29quinoline is 2 - (benzyl thio) quinoline, which is an organic compound with interesting chemical properties.
    2 - (benzyl thio) quinoline has aromatic properties, because both the quinoline ring and the benzyl sulfur part contain conjugated π electronic systems. Aromatic compounds often have special stability and electron delocalization characteristics, which make them unique in chemical reactions.
    In terms of solubility, the compound has very low solubility in water due to its hydrophobic quinoline ring and benzyl part. However, it is soluble in common organic solvents, such as chloroform, dichloromethane, ethanol, etc. This property is crucial for organic synthesis and separation and purification.
    In terms of chemical reactivity, the quinoline ring of 2 - (benzyl thio) quinoline can undergo electrophilic substitution reaction. The nitrogen atoms in the quinoline ring make the electron cloud on the ring uneven, and the specific position is more susceptible to electrophilic attack. For example, under appropriate conditions, halogen atoms, nitro and other functional groups can be introduced into the quinoline ring.
    Its benzyl thio-part, the sulfur atom has lone pair electrons, can participate in the reaction as a nucleophilic reagent. The C-S bond of benzyl thio-group can be broken under the action of specific reagents, and then various reaction pathways can be derived.
    In addition, the sulfur atom of 2 - (benzythio) quinoline can be oxidized to form sulfoxide or sulfone derivatives. The oxidation reaction conditions are different, and the products are also different.
    2 - (benzythio) quinoline has potential application value in organic synthesis, medicinal chemistry and other fields due to its unique chemical properties, and can provide important intermediates for the construction of more complex organic molecules.
    What are the synthesis methods of 2- (Benzylthio) quinoline
    2-%28Benzylthio%29quinoline is 2- (benzyl thio) quinoline. The method of synthesizing this compound can be obtained from several ways.
    First, quinoline can be reacted with benzyl mercaptan under appropriate catalyst and reaction conditions. To perform this reaction, it is necessary to prepare quinoline and benzyl mercaptan, and choose a suitable catalyst, such as some metal salts or organic bases. Place the reactants in a reaction vessel in a certain proportion and stir the reaction at an appropriate temperature and pressure. When reacting, pay close attention to factors such as temperature, reaction time and proportion of reactants, because these factors have an important impact on the yield of the reaction and the purity of the product. After the reaction is completed, the pure 2- (benzyl thio) quinoline can be obtained by suitable separation and purification methods, such as column chromatography, recrystallization, etc.
    Second, the quinoline can be functionalized first, and an active group that is easy to react with benzyl mercaptan can be introduced. For example, the quinoline is halogenated to obtain halogenated quinoline, and then the halogenated quinoline undergoes a nucleophilic substitution reaction with benzyl mercaptan. In this approach, the halogenation step requires the selection of suitable halogenating agents and reaction conditions to ensure that halogen atoms are selectively introduced into the appropriate position of the quinoline. During the nucleophilic substitution reaction, the preparation of benzyl mercaptan and the control of reaction conditions are also critical. Similarly, after the reaction is completed, the target product is obtained by separation and purification.
    Third, the cross-coupling reaction catalyzed by transition metals can be used to synthesize. For example, with the help of transition metal catalysts such as palladium and copper, the sulfur-containing reagents are cross-coupled with quinoline derivatives. This method requires precise control of the amount of catalyst, the selection of ligands and the reaction solvent to promote the efficient and selective reaction. After the reaction is completed, the separation and purification steps are carried out regularly to obtain 2- (benzythio) quinoline. In short, there are various methods for synthesizing 2- (benzythio) quinoline, each with its own advantages and disadvantages. The actual synthesis needs to be based on specific conditions, such as raw material availability, cost, product purity requirements, etc., and the appropriate synthesis path should be carefully selected.
    What are the precautions for using 2- (Benzylthio) quinoline?
    2-%28Benzylthio%29quinoline is 2- (benzythio) quinoline. During the use of this substance, the following things must be paid attention to:
    First, safety protection must not be taken lightly. 2- (benzythio) quinoline may be toxic and irritating. When operating, be sure to wear suitable protective equipment, such as gloves, goggles, gas masks, etc., to prevent skin contact, inhalation or ingestion. After the operation, the contact area should be washed with soap and water in time. If you accidentally contact the eyes, rinse with plenty of water immediately and seek medical attention quickly.
    Second, storage conditions are also crucial. Store it in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent fire or explosion. At the same time, it must be stored separately from oxidizing agents, acids, alkalis and other substances to avoid dangerous chemical reactions caused by mixed storage.
    Third, ventilation of the use environment is indispensable. When operating, it is necessary to ensure that the workplace has good ventilation conditions. It is best to operate in a fume hood to reduce the concentration of 2- (benzythio) quinoline in the air and reduce the risk of inhalation.
    Fourth, strictly follow the operating procedures. Before use, you should be familiar with the relevant experiments or production processes, accurately control the usage and reaction conditions, and must not change the established process parameters at will to avoid unnecessary accidents.
    Fifth, waste disposal should not be ignored. Waste after use should be properly disposed of in accordance with relevant regulations and should not be discarded at will. In general, it needs to be handled harmlessly by a professional recycling agency to prevent environmental pollution.