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What is the chemical structure of 2-Amino-3- (2-dihydro-2-oxoquinoline-4-yl) propanoic acid hydrochloride
This is the problem of 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride. To know its chemical structure, let me tell you in detail.
According to its name, the 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid part, the structure of propionic acid is\ (CH_3CH (COOH) \), and a substituent is introduced at its No. 3 position. This substituent is 1, 2-dihydro-2-oxyquinoline-4-yl, quinoline is a nitrogen-containing heterocyclic aromatic hydrocarbon with a benzopyridine structure. In this substituent, 1, 2-dihydro means that the double bonds of the 1 and 2 positions of the quinoline ring are hydrogenated, and 2-oxygen represents the carbon atom at the 2 position of Ming with a double bond to an oxygen atom. And because it is connected to the 3 position of propionic acid, that is, a hydrogen atom on the 3 position of the substituted propionic acid.
And the hydrochloride salt is obtained by forming a salt of this organic compound with hydrochloric acid. When the organic compound has a basic group, such as an amino group, it can combine with the hydrogen ion in hydrochloric acid to form a salt. The amino group of this compound obtains hydrogen ions to form positively charged ammonium ions, and chloride ions form salts with it.
In summary, the chemical structure of 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride is the core of the propionic acid skeleton, which is connected to 1, 2-dihydro-2-oxyquinoline-4-yl in 3 positions, and the amino group is in the form of hydrochloride. This structure makes the compound have specific physical and chemical properties and may have important uses in organic synthesis, medicinal chemistry and other fields.
What are the main uses of 2-Amino-3- (2-dihydro-2-oxoquinoline-4-yl) propanoic acid hydrochloride
2-Amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride has a wide range of uses. In the field of pharmaceutical development, it may be a key intermediate for the synthesis of specific drugs. Due to its specific chemical structure and activity, it can be integrated into the molecular structure of drugs through subtle reaction steps by means of organic synthesis, giving drugs specific pharmacological activities, such as the creation of drugs involved in regulating physiological functions and intervening in disease processes.
In the field of chemical research, it is also an important research object. By exploring its chemical properties and reaction characteristics, researchers can gain insight into the reaction mechanism of organic compounds, develop novel synthesis paths, and enrich the theoretical system of organic chemistry. And because its structure contains specific functional groups, it can trigger a variety of chemical reactions, providing opportunities and challenges for the development of organic synthetic chemistry.
In the field of biochemistry, or interact with specific biomacromolecules in organisms, such as proteins, nucleic acids, etc. This interaction may affect the structure and function of biomacromolecules, and then interfere with physiological and biochemical processes in organisms. The study of the mechanism of their interaction with biomacromolecules helps to deeply understand the essence of life activities and provides important information for basic research in biochemistry.
In addition, it has made a name for itself in materials science. After appropriate modification and modification, functional materials with special properties may be prepared, such as materials with the ability to identify and adsorb specific substances, which may have extraordinary application potential in separation, detection and other fields.
What are the physical properties of 2-Amino-3- (2-dihydro-2-oxoquinoline-4-yl) propanoic acid hydrochloride
2-Amino-3- (1,2-dihydro-2-oxoquinoline-4-yl) propionic acid hydrochloride, this is an organic compound. Looking at its physical properties, it is mostly solid at room temperature. White or off-white crystalline powders are common in appearance, but their color may vary slightly due to purity. Pure ones are as white as snow, and slightly gray with slightly more impurities.
In terms of solubility, this substance may have a certain solubility in water. Water is a common solvent. Polar groups contained in its molecular structure, such as amino and carboxyl groups, can form hydrogen bonds with water molecules to promote their dissolution. However, its solubility in organic solvents varies greatly depending on the type of solvent. In polar organic solvents, such as methanol and ethanol, the solubility is good; in non-polar organic solvents, such as benzene and n-hexane, it is difficult to dissolve.
Melting point is an important physical property for identifying the compound. Heating this substance to a specific temperature, the lattice structure disintegrates, and the solid state turns to a liquid state. This temperature is the melting point. Accurate determination of the melting point can help to distinguish its purity. If the melting point is fixed and consistent with the literature value, the purity or high; if the melting point range is wide and deviates from the literature value, or contains impurities.
Furthermore, its hygroscopicity is also a property that cannot be ignored. In humid air, it can absorb water vapor, increase its own water content, or affect its stability and other physical properties, so it is necessary to pay attention to moisture protection when storing.
The physical properties mentioned above, such as appearance, solubility, melting point, hygroscopicity, etc., are of critical significance in the research, production, storage and application of this compound, providing an important basis for comprehensive understanding and rational use of this substance.
What are the synthesis methods of 2-Amino-3- (2-dihydro-2-oxoquinoline-4-yl) propanoic acid hydrochloride
The synthesis method of 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride has been around for a long time, and with the changes of time, the technology has become more and more exquisite. The details are as follows:
The method of the past depends on natural materials as the beginning. Find grass, wood, gold and stone rich in specific ingredients, and wash and grind them many times to make fine powder. Then, with the technique of combining water and fire, put them in a special pottery kettle to control their heat, or attack with fire, or simmer slowly. At a specific time, various additives are added. This additive is either a secret liquid or a refined powder, and it interacts with it to promote the reaction. However, this method takes a long time, and the product is impure and contains many impurities. It needs to be purified repeatedly to obtain usable products.
Today's synthesis is advanced in technology, and chemical synthesis is the mainstream. Quinoline compounds are often used as starting materials. Because their structure is similar to the target product, the desired structure can be precisely constructed by means of organic chemistry. First, quinoline is specially modified, and appropriate groups are introduced at specific positions. This step requires precise control of reaction conditions, such as temperature, pH, reaction time, etc. Then, the propyl structure containing amino and carboxyl groups is connected, and this process can be achieved by means of condensation reaction and substitution reaction. After the reaction is completed, it is acidified with hydrochloric acid to obtain the hydrochloride of the target product.
In order to make the reaction efficient and the product pure, advanced instruments and equipment are often used today. For example, high-performance liquid chromatography can monitor the reaction process, so that the degree of reaction can be known in real time, and the end point of the reaction can be accurately grasped; the structure of the product can be analyzed by nuclear magnetic resonance instrument, mass spectrometer, etc., to ensure that the obtained product is the target. In this way, the synthesized 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride is of good quality and can meet the needs of all parties.
2-Amino-3- (2-dihydro-2-oxoquinoline-4-yl) propanoic acid hydrochloride in storage and transportation
2-Amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride, this is a special chemical substance, when storing and transporting, many matters should be paid attention to.
First talk about storage, the temperature and humidity of the first environment. It should be placed in a cool, dry place to prevent deliquescence due to excessive humidity, and high temperature may cause chemical reactions and cause it to deteriorate. The warehouse temperature should not be higher than [X] ° C, and the relative humidity should be maintained below [X]%.
Furthermore, the storage place must be kept away from tinder and heat sources. Because it may have certain chemical activity, in case of open flame, hot topic, or risk of combustion and explosion. Therefore, smoking is strictly prohibited in the warehouse, and all kinds of electrical equipment must be explosion-proof.
At the same time, this substance should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Because of its special chemical properties, contact with the above substances, or violent chemical reactions occur, endangering safety.
As for transportation, the packaging must be tight and firm. Choose packaging materials that meet relevant standards to ensure that the packaging is not damaged or leaked during transportation. And the transportation process should be protected from rain and sun protection to avoid affecting its quality due to external environmental factors.
Transportation vehicles also need to take appropriate protective measures, equipped with fire extinguisher materials and leakage emergency treatment equipment. If a leak occurs during transportation, drivers and passengers should take emergency measures immediately to evacuate the crowd and prevent the spread of pollution.
In this way, careful storage and transportation of various precautions can ensure the safety of 2-amino-3- (1,2-dihydro-2-oxyquinoline-4-yl) propionic acid hydrochloride.