As a leading 2,9-bis(4-methoxybenzyl)isoquino[4',5',6':6,5,10]anthra[2,1,9-def]isoquinoline-1,3,8,10(2H,9H)-tetrone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2,9-bis (4-methoxybenzyl) isoquino [4 ', 5', 6 ': 6,5,10] anthra [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetrone
This is an organic compound with a rather complex chemical structure. The compound is named 2,9-bis (4-methoxybenzyl) isoquinoline [4 ', 5', 6 ': 6,5,10] anthro [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetraone.
To view its structure, isoquinoline and anthranoisoquinoline are used as the basic structures. At positions 2 and 9, there is a 4-methoxybenzyl group attached to each. In "methoxybenzyl", the methoxy group (-OCH 🥰) is attached to the phenyl ring para-position of the benzyl group (phenyl). The anthracenoisoquinoline part contains multiple fused benzene rings and nitrogen heterocycles. There is a carbonyl group (C = O) at positions 1, 3, 8, and 10, which is in the state of tetraketone, and is occupied by hydrogen atoms at positions 2H and 9H. This structure gives the compound unique chemical and physical properties, or shows special application potential in organic synthesis, materials science and other fields.
What are the physical properties of 2,9-bis (4-methoxybenzyl) isoquino [4 ', 5', 6 ': 6,5,10] anthra [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetrone
2% 2C9 - bis% 284 - methoxybenzyl%29isoquino%5B4%27%2C5%27%2C6%27%3A6%2C5%2C10%5Danthra%5B2%2C1%2C9 - def% 5Disoquinoline - 1%2C3%2C8%2C10%282H%2C9H%29 - tetrone, which is an organic compound. Its physical properties are as follows:
The appearance is mostly crystalline, and the texture is relatively fine, like tiny crystal blocks gathered in one place. Under normal temperature and pressure stability, its color is usually light yellow, like the first color of autumn chrysanthemum, and like the faint light of morning light sprinkling on it.
The melting point is the key to measure the characteristics of this compound. Experiments have determined that the melting point of this substance is quite high, and a specific high temperature is required to cause it to melt from a solid state to a liquid state. Such a high melting point is due to the close arrangement and strong interaction force between its molecules. It is like a group of molecules holding hands and relying tightly on each other. Strong heat energy is required to break this stable structure.
Solubility is also an important physical property. In common organic solvents, its solubility varies. In some polar organic solvents, such as ethanol, there is a certain solubility, like fish entering water, some molecules can be evenly dispersed; in non-polar organic solvents, such as n-hexane, the solubility is very small, just like sand entering water, and it is difficult to blend with the solvent.
In addition, when the compound is in a solid state, it has a certain hardness and feels like a hard sand aggregate. Its density is slightly higher than that of water. If it is placed in water, it will slowly sink, like a stone sinking to the bottom. These physical properties are of great significance for their application and research in the fields of organic synthesis and materials science.
What is the synthesis method of 2,9-bis (4-methoxybenzyl) isoquino [4 ', 5', 6 ': 6,5,10] anthra [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetrone
To prepare 2% 2C9-bis (4-methoxybenzyl) isoquinoline [4 ', 5', 6 ': 6,5,10] anthrano [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetraketone, the method is as follows:
First take an appropriate amount of 4-methoxybenzyl halide and isoquinoline [4', 5 ', 6': 6,5,10] anthrano [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetraketone as raw material, in a suitable reaction vessel, add an appropriate amount of base to promote the reaction. Alkali, such as potassium carbonate, can maintain a suitable alkaline environment in the system, which is conducive to the occurrence of nucleophilic substitution reactions. Next, an appropriate amount of organic solvents, such as N, N-dimethylformamide (DMF), are added. This solvent has good solubility, which can fully mix the raw materials and disperse them uniformly in the system to improve the reaction efficiency.
Then, the reaction system is heated to an appropriate temperature, about 80 to 100 degrees Celsius. Within this temperature range, the reaction can proceed relatively smoothly. The benzyl moiety of 4-methoxybenzyl halide can be combined with isoquinoline [4 ', 5', 6 ': 6,5,10] anthrano [2,1,9 - def] isoquinoline-1,3,8,10 (2H, 9H) -tetraketone at a specific position Nucleophilic substitution reaction occurs, and the target product is gradually generated 2% 2C9-bis (4-methoxybenzyl) isoquinoline [4', 5 ', 6': 6,5,10] anthrano [2,1,9 - def] isoquinoline-1,3,8,10 (2H, 9H) -tetraketone < Br > During the reaction process, the reaction process needs to be closely monitored. By means of thin layer chromatography (TLC), when the raw material point disappears or reaches the expected degree of reaction, the heating is stopped and the reaction system is cooled. After cooling, pour the reaction liquid into an appropriate amount of water to quench the unreacted reagents and precipitate the product. Then, after extraction, washing, drying, column chromatography and other post-processing steps, a pure 2% 2C9-bis (4-methoxybenzyl) isoquinoline [4 ', 5', 6 ': 6,5,10] anthrano [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetraketone product can be obtained. In this way, the desired compound can be obtained.
In which fields is 2,9-bis (4-methoxybenzyl) isoquino [4 ', 5', 6 ': 6,5,10] anthra [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetrone used?
2% 2C9 - bis% 284 - methoxybenzyl%29isoquino%5B4%27%2C5%27%2C6%27%3A6%2C5%2C10%5Danthra%5B2%2C1%2C9 - def% 5Disoquinoline - 1%2C3%2C8%2C10%282H%2C9H%29 - tetrone, this chemical substance has applications in many fields.
In the field of medicine, its structure is unique or has specific biological activities. After research, it has been found that this substance may have effects on certain disease-related targets and can regulate specific biological pathways. For example, in tumor research, it may affect the proliferation and apoptosis of tumor cells, providing a direction for the development of new anti-cancer drugs. Although it may not be widely used in clinical practice, its potential medicinal value has attracted the attention of researchers.
In the field of materials science, this substance may endow materials with unique properties due to its special chemical structure. It can be used as a functional additive to improve the optical and electrical properties of materials. For example, it can be used to prepare new photoelectric materials to enhance the light absorption and charge transport capabilities of materials, and is expected to be applied to solar cells, Light Emitting Diodes and other photoelectric devices to improve their performance and efficiency.
In the field of organic synthesis, it can act as a key intermediate. With its complex structure and activity check point, through a series of organic reactions, more compounds with complex structures and diverse functions can be derived, which will contribute to the development of organic synthetic chemistry, expand the boundaries of synthetic chemistry, and help chemists create more new compounds.
What is the safety of 2,9-bis (4-methoxybenzyl) isoquino [4 ', 5', 6 ': 6,5,10] anthra [2,1,9-def] isoquinoline-1,3,8,10 (2H, 9H) -tetrone
2% 2C9 - bis% 284 - methoxybenzyl%29isoquino%5B4%27%2C5%27%2C6%27%3A6%2C5%2C10%5Danthra%5B2%2C1%2C9 - def% 5Disoquinoline - 1%2C3%2C8%2C10%282H%2C9H%29 - tetrone, this is a complex organic compound. When it comes to the safety of this compound, it needs to be examined from multiple aspects.
First look at its chemical structure, the compound contains many special functional groups and fused ring structures. Among them, the fused aromatic hydrocarbons may have potential biological activity and toxicity. Like fused aromatic hydrocarbons, some of them can be metabolically activated under specific conditions to generate electrophilic products, which bind to biological macromolecules such as DNA, causing gene damage and increasing the risk of cancer.
However, their safety is also affected by substituents. This compound contains 4-methoxybenzyl substituent, methoxy as the power supply subgroup, or changes the electron cloud distribution and chemical activity of the compound, affecting the mode and intensity of its interaction with targets in organisms. However, the specific impact of this substituent on safety still needs to be supported by experimental data.
Re-discussion on its behavior in the environment. If it is released into the environment, it will cause environmental residues due to its complex structure or difficulty in rapid degradation by microorganisms. Its potential toxicity to environmental organisms cannot be ignored, or it may affect the ecological community structure and function of aquatic organisms and soil microorganisms.
From the perspective of human exposure, if it enters the human body through inhalation, skin contact or accidental ingestion, it may be difficult to be processed by the normal metabolic pathways of the human body due to its complex structure. Or accumulate in specific tissues and organs in the body, interfere with normal physiological functions, and cause health problems. However, specific toxicological effects, dose-response relationships, and metabolic pathways all need in-depth experimental studies.
In summary, based on the available information, it is difficult to determine the safety of 2% 2C9 - bis% 284 - methoxybenzyl%29isoquino%5B4%27%2C5%27%2C6%27%3A6%2C5%2C10%5Danthra%5B2%2C1%2C9 - def% 5Disoquinoline - 1%2C3%2C8%2C10%282H%2C9H%29 - tetrone. More experimental studies are urgently needed to explore its toxicological properties, environmental behaviors, and human exposure risks in order to comprehensively evaluate the safety.