2 8 Bis Trifluoromethyl 4 Bromoquinoline
quinoline thiophene imidazole thiazole

2,8-Bis(Trifluoromethyl)-4-Bromoquinoline

Taiy Chemical

    Specifications

    HS Code

    956174

    Chemical Formula C11H4BrF6N
    Molecular Weight 358.05
    Appearance Typically a solid (description may vary by purity and conditions)
    Melting Point Data may vary, check literature for exact value
    Boiling Point Data may vary, check literature for exact value
    Solubility Solubility characteristics would depend on solvents; may be sparingly soluble in water, more soluble in organic solvents like dichloromethane
    Density Data may vary, check literature for exact value
    Vapor Pressure Low vapor pressure as it is likely a solid at room conditions
    Pka Data may vary, check literature for exact value
    Flash Point Data may vary, check literature for exact value

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    General Information
    Where to Buy 2,8-Bis(Trifluoromethyl)-4-Bromoquinoline in China?
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    Frequently Asked Questions

    As a leading 2,8-Bis(Trifluoromethyl)-4-Bromoquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,8-bis (trifluoromethyl) -4-bromoquinoline?
    2% 2C8-bis (triethylmethyl) -4-benzodimethylene light is a rare substance with unique physical properties. The appearance of this substance is often crystal clear, just like the carving of ice crystals, pure and flawless. Under the light, it reflects a fascinating brilliance, like a dream bubble.
    When it comes to the melting point, it is about a specific range. When the temperature is suitable, it will slowly melt from a solid state to a liquid state, just like spring snow melting under the warm sun. Its boiling point is also fixed. When it reaches this temperature, it will turn into a curling state, like light smoke.
    Furthermore, density is also one of its important physical properties. The density of this substance is moderate, it does not float or sink, as if it has found a balance in the world. In terms of solubility, in some specific solvents, it can quietly dissolve, as if it is integrated into it, and it is difficult to distinguish each other; in other solvents, it is incompatible, such as oil and water, which are distinct.
    Its hardness is moderate, not as hard as steel, difficult to carve; nor as soft as mud, untouchable. When tapped lightly, it will make a crisp sound, like jade hitting each other, with a lingering sound. The conductivity of this substance is weak, just like a trickle, and it is difficult to carry a strong current. In the circuit, it is like a bystander, rarely participating in the transmission of current.
    Such various physical properties make 2% 2C8-bis (triethyl) -4-benzodimethyl light unique in many fields, either as a raw material for delicate instruments or as a medium for wonderful reactions. It is a stunner with unique physical properties.
    What are the chemical properties of 2,8-bis (trifluoromethyl) -4-bromoquinoline
    2% 2C8-bis (triethylmethyl) -4-phthalic acid, this substance is an organic compound. Its chemical properties are unique, let me explain in detail for you.
    When it comes to physical properties, under normal conditions, it may be a solid, with a certain melting point and boiling point. Due to the molecular structure containing groups such as benzene ring and carboxyl group, its solubility is different. In organic solvents, such as ethanol and acetone, there may be a certain solubility; however, in water, the solubility may be limited. This is because the hydrophobicity of the benzene ring and the carboxyl group have a certain hydrophilicity, but under the overall influence, the water solubility is not good.
    Its chemical properties, the first is the reactivity of carboxyl group. The carboxyl group is an active functional group and can neutralize with bases. In case of sodium hydroxide, the corresponding carboxylate and water can be formed. This reaction is often used for acid-base neutralization and preparation of carboxylate compounds.
    The esterification reaction is also an important property. Under the catalysis of concentrated sulfuric acid and heating conditions, it can react with alcohols to form esters and water. This reaction is widely used in organic synthesis, and can prepare a variety of esters with special flavors and uses, which are of great value in flavors, coatings and other industries.
    In addition, the structure of benzene rings also gives it special chemical properties. Benzene rings are aromatic, relatively stable, and can undergo electrophilic substitution reactions. Such as halogenation reactions, under the catalysis of iron or iron salts, can be substituted with halogens to introduce halogen atoms on the benzene ring; in nitrification reactions, under the mixing of concentrated sulfuric acid and concentrated nitric acid, the benzene ring can introduce nitro groups to form nitro substituents.
    Because it contains multiple substituents, the intermolecular interaction is complex, or it affects its reactivity and selectivity. In organic synthesis and chemical production, the reaction conditions need to be carefully controlled to achieve the expected reaction effect and product purity.
    What are the common synthesis methods of 2,8-bis (trifluoromethyl) -4-bromoquinoline?
    The common synthesis methods of 2% 2C8-bis (triethylamino) -4-hydroxyphenyl fluorescence are as follows:
    ###Raw material preparation
    Triethylamine, p-hydroxybenzaldehyde, suitable phosphor and other raw materials, as well as corresponding catalysts and solvents, etc. The purity of the raw materials has a great impact on the reaction effect, so it needs to be carefully purified to meet the reaction requirements.
    ###Reaction steps
    1. ** First step reaction **: Place an appropriate amount of p-hydroxybenzaldehyde and triethylamine in a reaction vessel according to a specific molar ratio, and add suitable organic solvents, such as toluene, dichloromethane, etc., to help the reactants mix evenly, so that the reaction can proceed smoothly. In this system, add an appropriate amount of catalyst, such as some organic base catalysts. Turn on the stirring device to allow the reactants to fully contact, and at the same time adjust the reaction temperature to a specific range, usually between 40-60 ° C. This step of the reaction is designed to make the substitution reaction of p-hydroxybenzaldehyde with triethylamine to form a preliminary intermediate product. The reaction lasts about 2-4 hours. During this period, the reaction progress can be monitored by thin layer chromatography (TLC). When the raw material point is basically eliminated, the reaction is considered to be basically completed.
    2. ** Second step reaction **: After the first step of the reaction is completed, the reaction system is cooled to room temperature. Then, add the prepared phosphor matrix, and also precisely control the molar ratio of it to the intermediate product. Adjust the reaction temperature again, generally raise the temperature to 80-100 ° C, and maintain this temperature for 6-8 hours. This step is a key step in the reaction, which aims to make the intermediate product and the phosphor matrix undergo condensation reaction to construct the basic structure of the target product. The reaction process is also monitored by TLC until the new product point no longer changes significantly.
    3. ** Product separation and purification **: After the reaction is completed, the reaction mixture is cooled to room temperature, followed by post-processing operations. The organic phase is usually separated by a liquid separation funnel, and then washed with an appropriate amount of dilute acid solution (such as dilute hydrochloric acid) to remove unreacted organic bases and other basic impurities. The organic phase is then washed with distilled water to neutral to remove residual acid. Subsequently, the organic phase is dried with anhydrous sodium sulfate to remove any remaining water. Finally, the organic solvent is removed by vacuum distillation to obtain a crude product. The crude product needs to be further purified, and column chromatography is often used. Using silica gel as the stationary phase, select a suitable eluent system, such as the mixed solvent of petroleum ether and ethyl acetate, separate by column chromatography, collect the eluent containing the target product, and then remove the eluent by reduced pressure distillation to obtain a high-purity 2% 2C8-bis (triethylamino) -4-hydroxyphenyl fluorescent product.
    During the entire synthesis process, precise control of reaction conditions, purity assurance of raw materials and reagents, and rigorous operation of each step are the keys to obtaining high-purity and high-yield target products.
    In which fields is 2,8-bis (trifluoromethyl) -4-bromoquinoline used?
    2% 2C8-bis (triethyl) -4-hydroxybenzaldehyde, which is useful in many fields.
    In the field of medicine, it is a key raw material for the synthesis of specific drugs. Due to its unique chemical structure and activity, it can participate in the construction of drug molecules, which has a great impact on the pharmacological activity and efficacy of drugs. For example, some drugs with antibacterial and anti-inflammatory effects, in the synthesis process, 2% 2C8-bis (triethyl) -4-hydroxybenzaldehyde plays an important role, helping to shape the precise molecular configuration of drugs, enhance their ability to bind to biological targets, and improve drug efficacy.
    In the field of materials science, it can be used as an important component in the synthesis of functional materials. For example, in the preparation of some special optical materials, the introduction of this substance can improve the optical properties of the material, such as adjusting the material's light absorption and luminescence properties, so that it can show unique advantages in optical sensors, optoelectronic devices, etc., providing the possibility for technological innovation in related fields.
    In the field of organic synthetic chemistry, 2% 2C8 -bis (triethyl) -4 -hydroxybenzaldehyde is an extremely important intermediate. With its active chemical properties, it can react with various reagents through various organic reactions to construct complex organic molecular structures. Organic chemists can use this to synthesize a series of organic compounds with novel structures and specific functions, injecting new vitality into the development of organic synthetic chemistry and expanding the synthesis path and scope of organic compounds. < Br >
    In the fragrance industry, because of its special smell and chemical stability, it can be used to prepare unique fragrances. After ingenious formula design, it can give fragrances a unique aroma level and lasting fragrance effect, meeting the pursuit of aroma quality by different consumers, and is widely used in perfumes, air fresheners and other products.
    What is the market price of 2,8-bis (trifluoromethyl) -4-bromoquinoline?
    It is difficult to determine the market price of 2,8-bis (triethylamino) -4-cyanofluorescence today. The price of this fluorescent material is determined by various factors.
    First, the price of raw materials is the main factor. If the price of the raw materials required for this fluorescent product is high, or due to the special origin, difficulty in procurement, and shortage of supply, the cost can rise, and the market price will also increase accordingly.
    Second, the simplicity and efficiency of the production method are also related to the price. If the production method is exquisite, but the process is complicated, takes a long time, consumes a lot of manpower and material resources, or the equipment used is expensive and the maintenance is expensive, the price of the fluorescent material produced will be expensive. On the contrary, if the production method is simple and efficient, the cost will be reduced, and the price may be close to the people.
    Third, the supply and demand of the market will determine the price. If this product is in the market, and there are many people who want it, the supply is in short supply, and the merchants will see an opportunity to raise the price; if the supply exceeds the demand, the merchants will sell the product, or reduce the price to attract customers.
    Fourth, the quality is also the difference between the price. Those with high quality have good fluorescence efficiency and strong stability. They are suitable for high-end domains, and the price is high; those with lower quality are difficult to enter the high-demand market, and the price is also low.
    There are multiple taxes and transportation fees, or the price may be affected. If the tax is heavy, the merchant will be at the expense of the price; if the transportation distance and high cost are high, the price will also rise.
    From this perspective, if you want to know the price of 2,8-bis (triethylamino) -4-cyanofluorophore in the market, you must consider various factors in detail, and it cannot be generalized.