2 6 Bis Trifluoromethyl Quinoline 4 Carbonitrile
quinoline thiophene imidazole thiazole

2,6-bis(trifluoromethyl)quinoline-4-carbonitrile

Taiy Chemical

    Specifications

    HS Code

    718662

    Chemical Formula C12H4F6N2
    Molar Mass 304.166 g/mol
    Appearance Solid (predicted)
    Boiling Point 299.19°C at 760 mmHg (predicted)
    Melting Point 136 - 138°C
    Density 1.539 g/cm³ (predicted)
    Logp 3.84 (predicted)
    Pka -2.06±0.10 (predicted)
    Solubility In Water Insoluble (predicted)
    Flash Point 134.72°C (predicted)

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    General Information
    Where to Buy 2,6-bis(trifluoromethyl)quinoline-4-carbonitrile in China?
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    Frequently Asked Questions

    As a leading 2,6-bis(trifluoromethyl)quinoline-4-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-bis (trifluoromethyl) quinoline-4-formonitrile?
    2% 2C6-bis (triethylamino) fluorescent-4-ethanesulfonic acid, often used as a biological buffer, is of great significance in biochemical and molecular biology experiments.
    Its primary use is to maintain the pH stability of the system. Chemical reactions in organisms are extremely sensitive to pH, and small changes may affect enzyme activity and biomolecular structure functions. This substance has good buffering ability, which can maintain the pH of the reaction system within a specific range to ensure the normal progress of biochemical reactions. For example, in protein purification and analysis experiments, it can stabilize the pH of the solution, prevent protein from denaturing due to pH changes, and ensure reliable experimental results.
    is also indispensable in patch clamp technology. This technology is used to study the electrical activity of ion channels, which requires precise control of the composition and pH of the solution inside and outside the cell. 2% 2C6-bis (triethylamino) fluorescence-4-ethanesulfonic acid can create a stable pH environment, enabling researchers to accurately record ion channel currents and explore their physiological and pathological mechanisms.
    In addition, it has made great contributions to the field of cell culture. Cell growth requires strict environmental requirements, and appropriate pH is a key factor. Adding this substance to cell culture medium can maintain a stable pH, create suitable conditions for cell growth and reproduction, and improve the success rate and quality of cell culture.
    In summary, 2% 2C6-bis (triethylamino) fluorescence-4-ethanesulfonic acid plays a key role in many biomedical experiments and research links by maintaining pH stability, promoting the development of life sciences.
    What are the synthesis methods of 2,6-bis (trifluoromethyl) quinoline-4-formonitrile?
    The synthesis method of 2% 2C6-bis (triethylamino) fluorescent-4-cresol is a very important topic in the field of organic synthesis. Its synthesis path, there are many strategies.
    One is that the target molecule can be constructed by multi-step reaction starting from the basic organic compound. For example, using compounds containing phenolic hydroxyl groups as raw materials, the phenolic hydroxyl groups are first protected to prevent their unprovoked participation in the subsequent reaction and affect the reaction process. The choice of this protective group needs to be in line with the subsequent reaction conditions, which is easy to introduce and easy to remove at a suitable stage.
    Then, after the halogenation reaction, the halogen atom is introduced at the appropriate position, and the halogen atom is the key activity checking point for the subsequent nucleophilic substitution reaction. Then, the nucleophilic substitution reaction with triethylamine is carried out, so that the triethylamino group is introduced into the molecular structure. In this step, the control of reaction conditions is particularly critical, such as reaction temperature, reaction time and the proportion of reactants, which will affect the reaction yield and selectivity.
    Second, there are also fluorescein-like compounds as starters. On the basis of the structure of such compounds, some of the required fluorescent skeletons have been modified to introduce cresol and bis (triethylamino) structures. First, the specific position of fluorescein is chemically modified to change its electron cloud distribution and reactivity. Then, through ingeniously designed reaction steps, cresol groups and bis (triethylamino) groups are gradually introduced. In this process, the selectivity of each step of the reaction needs to be precisely controlled to ensure the formation of the target product.
    Third, there is a strategy to use transition metal catalysis. Transition metal catalysts can effectively promote the formation of various chemical bonds, improving the efficiency and selectivity of the reaction. For example, the coupling reaction catalyzed by palladium can achieve the efficient construction of carbon-carbon bonds and carbon-nitrogen bonds. The synthesis of 2% 2C6-bis (triethylamino) fluorophosphor-4-cresol can be achieved by rational selection of substrate and catalyst and optimization of reaction conditions. Although this method requires high equipment and operation, it can provide a more convenient and efficient way for synthesis.
    What are the physicochemical properties of 2,6-bis (trifluoromethyl) quinoline-4-formonitrile?
    The physicochemical properties of 2% 2C6-bis (triethylidene) -4-methylthio are as follows:
    The color state of this substance is often [specific color state, because it is not clear, it needs to be determined experimentally here], and the smell is specific, which needs to be carefully identified by experiments. Its melting point is in a specific temperature range [specific melting point range needs to be experimentally determined]. This characteristic is crucial in identification and purification, and can be accurately measured by melting point meters. The boiling point also occupies a specific range [specific boiling point range needs to be experimentally determined]. This data can be obtained through a distillation device. The boiling point is of great significance for separation and refining.
    In terms of solubility, in water [explain the solubility in water, such as insoluble, slightly soluble, etc., need to be determined experimentally], in common organic solvents such as ethanol, ether, and chloroform, the solubility varies [respectively describe the solubility in different organic solvents, need to be determined experimentally]. According to the principle of similarity compatibility, it can be inferred that the source of differences in solubility in different solvents.
    Its chemical properties have specific chemical activities. Contains specific functional groups, such as [indicate the specific functional groups contained], these functional groups determine its main chemical properties. Can participate in many chemical reactions, such as [list typical types of chemical reactions that may participate, such as substitution reactions, addition reactions, etc.]. Under specific conditions, such as temperature and catalyst, react with specific reagents [give examples of specific reactions and conditions that may occur].
    Stability is also an important property. Under normal temperature and pressure, [describe the stability at room temperature and pressure, such as stable, relatively stable, etc.], but under extreme conditions such as high temperature, strong oxidants, strong acids and alkalis, [explain the changes under these extreme conditions]. In-depth investigation of its physical and chemical properties can provide solid theoretical support and practical guidance for its rational application in [list possible application fields, such as chemical production, materials science, etc.].
    What is the price range of 2,6-bis (trifluoromethyl) quinoline-4-formonitrile in the market?
    I look at your question, but I am inquiring about the price of 2,6-bis (triethylamino) diphenyl-4-ethanesulfonic acid in the market. However, the market conditions of this product often change due to the quality of the quality, the amount of supply, and the rise and fall of the demand, and the exact number is not easily determined.
    Or in the market, the price of this product is different. If its quality is refined, the system is good, and the supply is small and the demand is numerous, the price will be high; if the quality is average, the system is regular, and the supply is large and the demand is slow, the price will be low. And times change, and the price will change accordingly.
    I have heard that the price of such products ranges from tens to hundreds of dollars per catty. However, this is only an approximate number, and it cannot be determined. To know the details, when you visit Jia people in various cities, the genus of medicine shops, or ask for the records of various commercial cities, you can get a near-real price.
    Therefore, if you want to obtain the confirmed price of 2,6-bis (triethylamino) diphenyl-4-ethanesulfonic acid, you must personally enter the market to inquire, or observe the reports of business conditions, in order to know the price range, so as not to be confused by the approximate number.
    What are the storage conditions for 2,6-bis (trifluoromethyl) quinoline-4-formonitrile?
    2% 2C6-bis (triethylamino) fluorescent-4-ethanesulfonic acid, this substance should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources and prevent direct sunlight. Due to its relatively active chemical properties, if the storage environment temperature is too high or the humidity is too high, it is easy to cause chemical reactions and lead to material deterioration.
    The container in which the substance is stored must be tightly sealed to avoid contact with air. Because it may react with certain components in the air, such as oxygen, water vapor, etc. At the same time, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent dangerous interactions. The storage place should be equipped with suitable materials to contain the leakage, so that in the event of accidental leakage, it can be dealt with in time and reduce hazards.
    Light handling is required during handling to prevent damage to packaging and containers. For storage warehouses, corresponding firefighting equipment and leakage emergency treatment equipment should be provided. Warehouse management personnel need to be professionally trained, familiar with the characteristics and storage precautions of the substance, and strictly follow relevant operating procedures, so as to ensure the safety and quality stability of 2% 2C6-bis (triethylamino) fluorescent-4-ethanesulfonic acid during storage.