Name | 2,4-Quinolinediol |
Molecular Formula | C9H7NO2 |
Molar Mass | 161.16 g/mol |
Appearance | Solid |
Melting Point | Decomposes |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in some organic solvents like DMSO |
Pka | pKa1: ~4.2; pKa2: ~10.5 |
Uv Absorption | Absorbs in UV region, specific peaks depend on solvent |
Ir Characteristic Peaks | Characteristic peaks for OH, C=O, and aromatic C - H vibrations |
What are the chemical properties of 2,4-quinolinediol?
2% 2C4-square, light dianhydride, that is, 2,4-toluene, diformic anhydride, its chemical properties are as follows:
2,4-toluene, diformic anhydride is white, crystalline, powder-like. This substance has the typical type of acid anhydride, chemical properties, encounter, water-prone, occurrence, hydrolysis, reaction, generating 2,4-toluene, diformic acid. Its hydrolysis reaction can be expressed as:\ (C_ {9} H_ {6} O_ {3} + H_ {2} O\ longrightarrow C_ {9} H_ {8} O_ {4}\).
2,4 -toluene, diformic anhydride can react with alcohols to form esters, compounds. For example, when reacting with methanol, it will generate 2,4-toluene, dicarboxylic acid, monomethyl ester or 2,4-toluene, dicarboxylic acid, dimethyl ester, depending on the amount of reaction, strip, and alcohol, and anhydride, depending on the ratio. For example, the reaction equation for the generation of 2,4-toluene, dicarboxylic acid, and dimethyl ester is:\ (C_ {9} H_ {6} O_ {3} + 2CH_ {3} OH\ longrightarrow C_ {11} H_ {12} O_ {4} + H_ {2} O\). < Br >
In the presence of amines, 2,4-toluene and diformic anhydride react with amines to form amides, compounds. This reaction is often used in organic synthesis to prepare amide-containing compounds. < Br >
2,4-toluene, diformic anhydride has certain thermal stability, but at relatively high temperatures, decomposition reactions will occur. The decomposition products vary depending on the reaction and the strips, and may include benzene, toluene, etc., aromatic, hydrocarbons, compounds and, some, small molecule gases.
Since the molecule of 2,4-toluene and diformic anhydride contains the benzene ring, it can be replaced by the reaction on the aromatic ring, such as halogenation, reaction, nitration reaction, etc., so as to introduce the corresponding substitution, group, on the benzene ring, as the further organic, synthetic, supply, diversity. For example, in the presence of a suitable catalyst, under the reaction of chlorine gas, chlorine-substituted 2,4-toluene and diformic anhydride can be formed.
In addition, 2,4-toluene and diformic anhydride can also be used as key intermediates in organic synthesis, used to synthesize various compounds with special structures and functions, and have a wide range of applications in the fields of pharmaceuticals, pesticides, high molecules, materials, etc.
What are the common synthesis methods of 2,4-quinolinediol?
The common synthesis methods of 2% 2C4-difluorodiphenyl ether are as follows:
One is the Ullmann reaction method. This is the classic synthesis path. In the past, copper powder was mostly used as a catalyst to react halogenated aromatics with phenolic compounds in high temperature and alkaline environment. For example, 2-chloro-4-fluorophenol and 2-fluorochlorobenzene were used as raw materials, catalyzed by copper powder, supplemented by alkalis such as potassium carbonate, and reacted in a sealed system at a higher temperature. In this reaction, copper powder catalyzed the substitution between halogen atoms and phenolic hydroxyl groups. After complex steps such as oxidative addition and reduction elimination, 2% 2C4-difluorodiphenyl ether was finally obtained. However, the traditional Ullmann reaction requires high temperature, and the equipment requirements are quite high, and the yield is often limited.
The second is the cross-coupling reaction catalyzed by palladium. This is a popular method in recent years. Palladium complexes are often used as catalysts, such as tetra (triphenylphosphine) palladium, etc., with aryl halide and phenol derivatives as raw materials, in the presence of suitable ligands and bases. For example, 2-bromo-4-fluorophenylboronic acid and 2-fluorophenylboronic acid are used as starting materials, cesium carbonate is used as a base, and the reaction is carried out at a relatively mild temperature (such as 80-100 ° C) in an organic solvent under the action of palladium catalyst. The method has good selectivity, mild reaction conditions, high yield, and can effectively avoid many side reactions.
The third is to synthesize phenolic compounds through a series of reactions such as diazotization and fluorination. First, the phenolic compounds are converted into diazonium salts, and then fluorine atoms are introduced through the Sandmeyer reaction or the Schiemann reaction. For example, using 2-amino-4-fluorophenol as raw material, diazonium salts are first prepared by diazotization reaction, and then by Sandmeier reaction, using fluoroboronic acid as fluorine source, diazo groups are converted into fluorine atoms, and then with another halogenated aromatic hydrocarbon through nucleophilic substitution reaction to obtain the target product 2% 2C4-difluorodiphenyl ether. This path has a little more steps, but it is also a feasible method when specific raw materials are available.
In which fields is 2,4-quinolinediol used?
2% 2C4-planar binaphthalene is useful in many fields. In the field of medicine, its unique chemical structure makes it stand out in drug development. It can be modified and modified to synthesize compounds with specific pharmacological activities, or used as drug carriers to facilitate precise drug delivery, improve drug efficacy and reduce side effects.
In the field of materials science, 2% 2C4-planar binaphthalene can greatly improve material properties. When preparing Organic Light Emitting Diode (OLED), adding this substance can optimize luminous efficiency and stability, resulting in clearer display screens and more brilliant colors. In polymer materials, it can act as a cross-linking agent or modifier to enhance the mechanical properties and thermal stability of the material, making the material stronger and more durable.
In the field of sensors, 2% 2C4-planar dinaphthalene is very useful due to its sensitive response characteristics to specific substances. When there is a target analyte in the environment, it can produce detectable physical or chemical changes, so as to develop high-sensitivity sensors for detecting biomolecules, heavy metal ions, etc., which is of great significance in food safety detection and environmental monitoring.
In the field of organic synthesis, 2% 2C4-planar dinaphthalene is an extremely critical intermediate. With its unique structure, it can participate in a variety of organic reactions to synthesize complex organic compounds, injecting new vitality into the development of organic synthetic chemistry and promoting the continuous emergence of innovative compounds and materials.
What is the market price of 2,4-quinolinediol?
In today's world, business conditions change, and the market price of 2,4-tetradecanhydride also rises and falls with many factors.
The determination of its price is primarily related to the trend of supply and demand. If there are many people in the market who want it, but there are few people who produce it, the price will rise. The demand for cover is prosperous and the supply is in short supply, like the water on a boat, its price will rise. In recent years, due to the vigorous development of electronics and medicine, the demand for 2,4-tetradecanhydride has increased greatly. The electronics industry produces special materials, and the pharmaceutical industry researches new drugs, all rely on this material, so that the demand for it exceeds the supply, and the price will rise.
Furthermore, the number of costs is also the price of the cardinal. The production of 2,4-square acid dianhydride requires all kinds of raw materials, and the rise and fall of its price is directly related to the cost. If the price of raw materials rises, if the material for building a building is expensive, the cost of making this material will increase, and the price between the cities will also rise accordingly. And the production method and the simplicity of the process are also related to the cost. If the new technique is released, which can save materials and time, and reduce the cost, the price may have the opportunity to drop; on the contrary, the old method is difficult to change, the cost is high, and the price is also difficult to drop.
Again, changes in the current situation and government regulations also affect the price. If the government strictly regulates chemical production and sets many regulations, the production will be limited, and the quantity will be reduced and the price will rise. Or there may be trade disputes, tariffs increase or decrease, cross-border supply and demand are blocked, and prices fluctuate.
As for the current market price, it is about [X] yuan per kilogram. However, this is only a temporary number, and the market conditions are ever-changing, so it cannot be argued. Businesspeople should have insight into the current situation, and clearly observe supply and demand, costs, and decrees, in order to grasp the changes in the market price of 2,4-tetradecanoic acid in the business sea, seek business opportunities, and lead to prosperity.
What are the safety and toxicity of 2,4-quinolinediol?
2% 2C4-difluorodioxycyclohexane, although this substance is not recorded in Tiangong Kaiwu, its safety and toxicity are discussed from a scientific perspective.
In terms of safety, 2% 2C4-difluorodioxycyclohexane is more active because its chemical structure contains fluorine and oxygen heterocycles. When storing, it is necessary to keep away from open flames and hot topics, because it may be flammable, in case of hot topics or open flames, or cause combustion or even explosion, endangering the safety of the surrounding area. At the same time, because of its chemical activity, or react with various substances, storage should avoid mixing with oxidants, reducing agents, etc., to prevent accidental reactions.
Toxicity level, 2% 2C4-difluorodioxane may be toxic to organisms. If inhaled through the respiratory tract, or irritate the respiratory mucosa, cause cough, asthma, or even cause more serious respiratory diseases. If exposed to the skin, or cause skin irritation, allergies, redness, swelling, itching and other symptoms. If accidentally ingested, or damage the digestive system, causing vomiting, abdominal pain, etc. And long-term low-dose exposure, or potential chronic effects on the nervous system, endocrine system, etc.
In summary, when using and storing 2% 2C4-difluorodioxane, it is necessary to strictly follow the safety operating procedures and take protective measures to ensure safety.