What is the chemical structure of 2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] quinoline-3-carboxylic acid?

This is the name of an organic compound, in modern chemical expression, its name is "2 - [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] quinoline-3-carboxylic acid". To clarify its chemical structure, the following disassembly method should be followed.

First view "quinoline-3-carboxylic acid", it can be seen that this compound has a quinoline ring as the base and a carboxyl group attached to the third position of the quinoline ring. The quinoline ring is a double ring structure formed by fusing a benzene ring with a pyridine ring.

Look at "2 - [4-methyl-5-oxo-4 - (isopropyl) -4,5-dihydro-1H-imidazole-2-yl]", which is the substituent connected to the 2 position of the quinoline ring. Among them, "1H-imidazole" is a five-membered heterocyclic ring containing two nitrogen atoms, "4,5-dihydro" indicates that the 4 and 5 positions of the imidazole ring are hydrogenated by double bonds to form a single bond; "4-methyl" and "4-isopropyl" show that the imidazole ring has methyl and isopropyl at the 4 position; "5-oxo" means that the 5 position of the imidazole ring exists in the form of carbonyl (C = O).

The complete chemical structure of "2 - [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] quinoline-3-carboxylic acid" is obtained by connecting this substituent to the second position of the quinoline ring. Its structure has the characteristics of both the rigidity of the quinoline ring and the substituent of the imidazole ring. This structure may endow the compound with specific physical, chemical and biological activities, and may have important applications and research value in organic synthesis, medicinal chemistry and other fields.

What are the physical properties of 2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] quinoline-3-carboxylic acid?

2-%5B4-methyl-5-oxo-4-%28propan-2-yl%29-4%2C5-dihydro-1H-imidazol-2-yl%5Dquinoline-3-carboxylic acid, this is an organic compound, often called a specific quinoline carboxylic acid derivative. It has many physical properties, let me tell you one by one.

Looking at its properties, under room temperature and pressure, it is mostly solid, but the specific crystal form varies depending on the preparation conditions, either in needle-like crystals or in powder states. The color of this compound is usually almost white to light yellow, but if it contains impurities, the color may change.

When it comes to the melting point, the melting point of this compound is quite high, about 200-250 ° C. The high melting point is due to strong interactions between molecules, such as hydrogen bonds, van der Waals forces, etc. The strong interaction makes the molecules closely arranged, and a high energy is required to break the lattice and increase the melting point.

In terms of solubility, its solubility in water is very small. Although the carboxyl group in the molecule can form a hydrogen bond with water, the hydrophobic part of the molecule as a whole accounts for a large proportion, such as the quinoline ring and the imidazolinone structure containing isopropyl group, which makes it difficult to dissolve in water. However, in organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc., the solubility is relatively good. In dichloromethane, it is soluble at a certain temperature and can form a homogeneous solution, which is conducive to related reactions and separation operations.

In addition, the compound has certain stability. In a dry environment at room temperature, it can be stored for a certain period of time without significant decomposition. However, under extreme conditions such as strong acid, strong base or high temperature and high humidity, the molecular structure may change. If in a strong base solution, the carboxyl group may react, and the imidazolinone ring may also be affected to cause structural changes.

The physical properties of this compound have a profound impact on its application in chemical synthesis, drug development and other fields. Understanding these properties can better control its reaction and application.

Where is 2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] quinoline-3-carboxylic acid used?

2-%5B4-methyl-5-oxo-4-%28propan-2-yl%29-4%2C5-dihydro-1H-imidazol-2-yl%5Dquinoline-3-carboxylic acid, this is an organic compound with unique chemical structure and properties. It has applications in many fields, as detailed below:
1. ** Pharmaceutical field **: Such compounds containing quinoline and imidazole structures are often biologically active. The quinoline structure is found in many drugs, such as the antimalarial drug quinine; the imidazole structure is also commonly found in many biologically active molecules. Or by modifying the structure of this compound, new antibacterial and antiviral drugs can be developed. It may bind to key proteins of pathogens, interfere with the metabolic process of pathogens, and inhibit their growth and reproduction. In the development of anti-tumor drugs, it may interact with specific targets of tumor cells to block the proliferation signaling pathway of tumor cells and induce tumor cell apoptosis.
2. ** Material science field **: because of its specific chemical structure and electronic properties, or can be used to prepare functional materials. For example, in the field of organic optoelectronic materials, or can be reasonably designed and synthesized to prepare materials with specific optical and electrical properties. Or can be used to prepare organic Light Emitting Diode (OLED), using its luminescent properties under the action of an electric field to achieve efficient luminescence, applied to display technology to improve display quality and efficiency.
3. ** Agricultural field **: Similar structural compounds or have insecticidal and bactericidal activities. Or can be developed as new pesticides for crop pest control. It can specifically target specific targets in pests or pathogens, destroy their physiological functions, and achieve the purpose of controlling pests and diseases. Compared with traditional pesticides, it is more environmentally friendly and selective, and has less impact on beneficial organisms, which is conducive to sustainable agricultural development.

What are the synthesis methods of 2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] quinoline-3-carboxylic acid?

2-%5B4-methyl-5-oxo-4-%28propan-2-yl%29-4%2C5-dihydro-1H-imidazol-2-yl%5Dquinoline-3-carboxylic acid is 2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] quinoline-3-carboxylic acid, and its synthesis methods are diverse. The following are common methods.

The starting material is quinoline-3-carboxylic acid and the corresponding imidazole derivatives containing isopropyl and methyl. In one method, the quinoline-3-carboxylic acid is modified with appropriate protective groups to make the specific position activity suitable. After that, the modified quinoline-3-carboxylic acid and imidazole derivatives containing isopropyl and methyl are put into suitable organic solvents, and then catalyzed by bases to promote nucleophilic substitution reactions between the two. Bases such as potassium carbonate, sodium carbonate, etc. Organic solvents can choose dichloromethane, N, N-dimethylformamide, etc. The reaction temperature is adjusted according to the specific situation, or at room temperature, or heated to reflux, so that the reaction can advance towards the formation of the target product.

Another method is to prepare imidazole intermediates containing active groups first, and then react with quinoline-3-carboxylic acid derivatives. The imidazole derivative containing a halogen atom is formed by reacting with a suitable halogen with imidazole. The halogen atom has high activity, which is conducive to subsequent reactions. The derivative is then reacted with quinoline-3-carboxylic acid in the presence of a metal catalyst, such as a palladium catalyst, by means of catalysis to realize the coupling of the two to form the target product. This process requires strict control of the reaction conditions, such as temperature and catalyst dosage, to improve the reaction yield and selectivity.

In addition, the target molecular structure can be gradually constructed through a multi-step reaction. The imidazole ring is first constructed, and then it is connected to the quinoline ring and a carboxyl group is introduced. The imidazole ring structure was formed by condensation, cyclization and other reactions with suitable amines, aldose and ketones as starting materials. After that, the imidazole ring was connected to the quinoline ring through functional group conversion, coupling reaction, etc., and the carboxyl group was introduced at the appropriate position to obtain 2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] quinoline-3-carboxylic acid. During the reaction process, the product of each step needs to be separated and purified to ensure the purity and quality of the final product.

What is the market outlook for 2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] quinoline-3-carboxylic acid?

There is now a product named 2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] quinoline-3-carboxylic acid. Looking at its market prospects, it is like a fog to be revealed, which needs to be studied carefully.

This product has potential in the field of pharmaceuticals. Due to its unique structure, it may be used as a precursor for targeted drugs. Nowadays, there is a growing demand for targeted drugs. If this compound can be researched and optimized to fit specific targets, it may be useful in the creation of anti-cancer, anti-inflammatory and other drugs. However, the research and development of new drugs is a long and difficult process, and it needs to go through many tests, from cell experiments to animal experiments, and then to human clinical trials. There are many barriers, all of which need to be carefully approached.

In the field of materials, although it is rarely seen for the time being, the technology is new, or it will be modified in the future for the preparation of special functional materials. Materials with specific adsorption and optical properties are also unknown. However, the research and development of materials also needs to consider the feasibility of cost and process.

Looking at the market competition, similar structural compounds or existing research and development exploration. If you want to come out on top, you need to start research quickly and find their unique advantages through innovative methods. And marketing activities are also critical, and it is necessary to cooperate with pharmaceutical companies and scientific research institutions to make the potential of this product fully available in the market. Although the future is uncertain, if you study hard over time, you may be able to gain a place in the market and bloom.