What is the chemical structure of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione?

This is the chemical structure analysis of (1S, 9S) -1 -amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione.

Looking at this lengthy name, it can be seen that this compound has a complex structure. Among them, (1S, 9S) is marked with the configuration of the chiral center, indicating the arrangement of the specific stereochemistry. " 1-Amino ", the number 1 position is connected to the amino group. The amino group is a nitrogen-containing functional group and is alkaline. It is often an active check point in chemical reactions and can participate in many nucleophilic reactions." 9-Ethyl ", indicating that the number 9 position is connected to the ethyl group, and the ethyl group is a saturated alkyl group, which has an impact on the hydrophobicity and spatial structure of the compound." 5-Fluorine "refers to the fluorine atom at the number 5 position, which has strong electronegativity, can change the molecular polarity and electron cloud distribution, and affect the physical and chemical properties of the compound." 9-Hydroxy ", the number 9 position also has a hydroxyl group, and the hydroxyl group is hydrophilic, which can form a hydrogen bond, which affects the solubility and reactivity of the compound. 4-Methyl ", that is, methyl at the 4th position, the introduction of methyl can change the molecular steric resistance and electronic effects.

Looking at the main structure," 1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione ", which is composed of multiple fused cyclic structures. The structures of benzo [de] pyran, indolicino, and quinoline fuse with each other to form a complex rigid skeleton. 10,13-Dione indicates that the 10 and 13 positions each have a carbonyl group, which is polar and has high chemical activity, and can participate in various reactions such as nucleophilic addition.

This compound may have potential applications in organic synthesis, medicinal chemistry and other fields due to its unique structure or special physical, chemical and biological activities.

What is the main use of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione?

(1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione, which is a complex organic compound. However, such compounds are rarely recorded in ancient books. Due to their complex structure, they are the products of modern chemical synthesis.

In the field of chemistry today, such compounds are mostly used for drug development. Due to their unique chemical structure or specific biological activity, they can act on specific targets in the human body. Or can regulate physiological processes, such as participating in the regulation of cell signaling pathways, affecting cell growth, differentiation and apoptosis.

In the development of anti-tumor drugs, such compounds may inhibit the proliferation of tumor cells, induce their apoptosis, block tumor angiogenesis, and bring hope for solving cancer problems. In the research of drugs for neurological diseases, it may regulate the transmission of neurotransmitters, improve neurological function, and assist in the treatment of Parkinson's disease, Alzheimer's disease and other diseases.

Although its use is not mentioned in ancient books, the integration of modern chemistry and medicine has endowed it with an important mission, which is expected to contribute to human health and well-being and open up a new world in the field of disease treatment.

What are the physical properties of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione?

(1S, 9S) -1 -Amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione, a complex organic compound. Its physical properties are critical and are relevant to many practical applications.

Let's talk about the appearance first. Under normal temperature and pressure, it may be a crystalline solid, just like a shining ice crystal. The crystal form is regular and orderly, which is caused by the clever arrangement of intermolecular forces. When powdered, it is delicate like dust, evenly distributed, like fine sand.

Then there is the melting point, which has a specific melting point. At a certain precise temperature, the lattice structure disintegrates, and the substance gradually melts from solid to liquid. This temperature is the inherent property of the compound, which is similar to the unique birthmark of a person. It can be used for purity identification. If impurities are mixed in, the melting point may drop and the melting range becomes wider.

The solubility cannot be ignored, and in organic solvents, it may show different dissolution characteristics. In polar organic solvents, such as methanol and ethanol, there may be a certain solubility. Due to the principle of "similar miscibility", polar molecules and solvent molecules attract each other and dissolve well; in non-polar organic solvents, such as n-hexane and benzene, the solubility may be extremely low. Due to the large difference in molecular polarity, the interaction force is weak.

In addition, density is also an important physical property, reflecting the mass of a unit volume of matter. Under specific conditions, there is a fixed value. This value affects the behavior of substances in different environments. In mixed systems, it is related to processes such as stratification and diffusion.

The physical properties of this compound, like the parameters of precision instruments, are of critical significance in the fields of chemical synthesis, drug development, materials science, etc., to help researchers gain a deeper understanding of its properties and apply it rationally in various practical scenarios.

(1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione What are the synthesis methods?

The synthesis of (1S, 9S) -1 -amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione is a key investigation in the field of organic synthesis. This compound has a unique and complex structure, and the synthesis path is full of thorns, requiring delicate strategies and superb skills.

Many talents in the past often followed a number of paths when synthesizing this compound. First, the basic structure of benzo [de] pyran and indolisinoquinoline is used as the starting material. First, fluorine atoms are introduced at specific positions of benzo [de] pyran by clever reactions. This step requires careful selection of reagents and conditions to prevent side reactions from breeding. Nucleophilic substitution or electrophilic substitution reactions can be used, depending on the characteristics of the raw material activity and the reaction check point.

Then, the structure of indolisinoquinoline is carefully constructed, during which multiple steps of reactions may be required, or through cyclization and condensation. In the construction process, it is crucial to control the stereochemistry. If you want to obtain the (1S, 9S) configuration, you need to use an asymmetric synthesis method. Chiral additives or chiral catalysts can be introduced to guide the reaction to a specific configuration.

When introducing substituents such as amino, ethyl, hydroxyl and methyl, there are also many considerations. If amino is introduced, aminolysis can be used. However, it is necessary to pay attention to the reaction temperature, time and proportion of reactants to ensure the selectivity of the reaction. Introduce alkyl groups such as ethyl and methyl, or alkylation reactions can be used to select suitable alkylation reagents and bases to ensure the smooth progress of the reaction. The introduction of hydroxyl groups can be achieved through hydrolysis, reduction and other reactions, and the influence on other functional groups should be taken into account.

In addition, during the synthesis process, the separation and purification of the reaction intermediates is extremely critical. After each step of the reaction, column chromatography, recrystallization and other methods are often used to ensure the purity of the intermediates and lay a good foundation for subsequent reactions. Synthesizing this compound is like a delicate chemical dance, and each step of the reaction needs to be closely coordinated to successfully obtain the target product.

What is the market outlook for (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione?

There is a product named (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione. The prospect of this product in the market is really related to many factors, so let me explain in detail.

Looking at the field of medicine, this compound has a unique structure or potential pharmacological activity. Today, medical research is often seeking new molecules to treat various diseases. If this substance is proved to have a definite curative effect on specific diseases, such as difficult diseases or diseases for which there is no good method, then the market demand will rise. And in today's pharmaceutical market, innovative drugs are competing for many companies. If it can stand out, enter clinical trials, and then be approved for marketing, the future will be bright.

Furthermore, the chemical industry is also a consideration. If its synthesis method can be optimized, the cost can be controlled, and the yield is considerable, it can be cost-effective in chemical production. The chemical industry often seeks efficient and economical products. If this product meets these standards, it may be favored by the chemical industry and applied to the preparation of related fine chemicals to broaden its market path.

However, there are also challenges. The difficulty of synthesis is related to the possibility of mass production; the depth and breadth of pharmacological research depends on whether it can be recognized by the medical community. Only by breaking these difficulties can it be used in the market.

Overall, (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-dione Although the future is uncertain, if it is developed effectively and overcome difficulties, it is expected to open up a world in the pharmaceutical and chemical markets.