What is the chemical structure of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione methanesulfonate hydrate (1:1:2)

This is the chemical structure description of (1S, 9S) - 1 - amino - 9 - ethyl - 5 - fluoro - 9 - hydroxy - 4 - methyl - 1, 2, 3, 9, 12, 15 - hexahydro - 10H, 13H - benzo [de] pyrano [3 ′, 4 ′: 6,7] indolicino [1,2 - b] quinoline - 10,13 - diketone methanesulfonate dihydrate (1:1:2). Its chemical structure is quite complex, composed of multiple cyclic structures fused to each other.

Looking at its name, the main structure contains benzo [de] pyrano [3 ′, 4 ′: 6,7] indolicino [1,2 - b] quinoline, and this core structure has been modified by multi-step derivatization. The 1 position is connected to an amino group, the 9 position is connected to an ethyl and a hydroxyl group, the 5 position has a fluorine atom, and the 4 position is a methyl group. The overall structure contains multiple chiral centers, and this (1S, 9S) specific configuration has a great influence on its biological activity or physical properties.

Furthermore, it exists in the form of methanesulfonate and binds to water in a ratio of 1:1:2 to form a hydrate. This salt formation and hydration form have significant effects on the solubility and stability of the compound. Such a complex chemical structure determines its specific uses and properties in the fields of medicine, chemical industry, etc., and also lays the foundation for related research and applications.

What are the uses of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione methanesulfonate hydrate (1:1:2)

(1S, 9S) - 1 - amino - 9 - ethyl - 5 - fluoro - 9 - hydroxy - 4 - methyl - 1,2,3,9,12,15 - hexahydro - 10H, 13H - benzo [de] pyrano [3 ', 4': 6,7] indolo [1,2 - b] quinoline - 10,13 - diketone methanesulfonate dihydrate (1:1:2), this medicine is widely used.

In the medical system, it is often used for the treatment of specific intractable diseases. It can have significant curative effect on some diseases of viscera and meridians, can regulate the flow of qi and blood, and return yin and yang to balance. For example, for all kinds of diseases caused by stagnation of qi and blood in the body and blockage of meridians, this medicine can dredge the qi machine, dissipate stagnation, make the meridians unobstructed, and relieve pain.

It can also act on the metabolism and transformation of human subtle substances, helping the normal play of viscera functions. For example, due to the dysfunction of the viscera, the movement of subtle substances is abnormal, and various diseases arise. This medicine can adjust the qi machine of the viscera, make the subtle transportation orderly, and improve the overall condition of the body.

Furthermore, for some diseases caused by the intersection of exogenous evil energy and internal disease, the medicine can be both internal and external, not only to eliminate exogenous evil, but also to regulate endogenous diseases, so that the body can recover health. In clinical application, it is often reasonably compatible with other medicines according to the specific symptoms and constitution of the patient, so as to achieve the best healing effect. It is an important medicine for physicians to treat diseases.

What is the synthesis method of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione methanesulfonate hydrate (1:1:2)

The synthesis of (1S, 9S) -1 -amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolo [1,2-b] quinoline-10,13-diketone methanesulfonate dihydrate (1:1:2) is an important matter in chemical synthesis. To make this substance, a specific method and precise steps need to be followed. < Br >
At the beginning, select the right raw material, and its quality and quantity must be precisely controlled. When the raw material is available, it can be changed under specific conditions by chemical reaction. If the appropriate solvent is selected, the appropriate temperature is adjusted, and the precise time is controlled, the reaction can proceed in an orderly manner.

Or first, based on a reactant, mix with others in a specific solvent at a certain temperature to interact and form an intermediate product. The structure and properties of this intermediate product need to be tested in detail to ensure that the reaction is correct. < Br >
Then, the intermediate product is reacted through other reactions, or new reagents are added, or the reaction conditions are changed, such as heating and cooling, adjusting pH, etc., so that the molecular structure is gradually transformed and the shape of the target product is gradually changed.

After the reaction is completed, it needs to be separated and purified. Pure (1S, 9S) -1 -amino-9 -ethyl-5 -fluoro-9 -hydroxy-4 -methyl-1,2,3,9,12,15 -hexahydro-10H, 13H -benzo [de] pyrano [3 ', 4': 6,7] indolo [1,2 - b] quinoline-10,13 -diketone methanesulfonate dihydrate (1:1:2) was obtained by extraction, crystallization, chromatography and other methods. Each step requires careful operation, and the results may be very different. Therefore, the synthesis method depends on precision and concentration.

What is the safety of (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione methanesulfonate hydrate (1:1:2)

(This is a long list of complex chemical names, hereinafter referred to as "this drug") The safety of this drug is related to many aspects, and it is difficult to hide it. Looking at its pharmacology, this drug has a unique structure, the interaction of chemical groups it contains is complex, or it affects human physiology. In animal experiments, or the reaction of specific organs may be seen, but human and animal physiology are different, and it cannot be fully believed. During clinical application, although it has been verified many times, there are still latent risks. If the dosage of the drug is not properly controlled, the efficacy of the drug will not be reached, and if it is heavy, the toxicity will suddenly appear, and the viscera will be damaged. And individual differences are also the key. Different people have different constitutions, and their tolerance and metabolism to the drug are different. There may be allergies, which endanger life. In addition, long-term use of this medicine, its long-term impact on the human body is difficult to predict, or it may cause chronic lesions, lurking in the body, and developing in time. Therefore, when doctors use drugs, they should carefully weigh the pros and cons, carefully observe the patient's condition, and strive for drug safety. Never be careless.

What is the market outlook for (1S, 9S) -1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1, 2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline-10,13-dione methanesulfonate hydrate (1:1:2)

Today there is a thing whose name is (1S, 9S) - 1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H, 13H-benzo [de] pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-10,13-diketone methanesulfonate dihydrate (1:1:2). This thing is worth exploring in front of the city.

To observe the scene in front of the city, it is necessary to observe many aspects. The first is the process of research and development. It has gone through research, and scientific researchers have made every effort to repeatedly try and error in the experimental room to study the nature, quality and effect of this thing. The difficulty of its research and development is like walking on a rugged road, step by step cautiously, lest there be mistakes.

Furthermore, it depends on the needs of the market. If this thing can solve the disease of the world, or meet the needs of a certain industry, its market scene is quite impressive. If doctors expect it to be a cure for diseases, and if industries expect it to help new materials, it will lead to an increase in demand.

However, there are also challenges. The bundle of regulations must be followed, and inspection and approval must be followed, strict and strict. And the competition is fierce, similar products may have entered the market first, and it is easier said than done to compete for a place.

Even if there are challenges, if it has unique advantages, outstanding curative effect, or extraordinary performance, it is also expected to emerge in the market, add new color to the city, and show its ability in the world.