1H-Benz(de)isoquinoline-1,3(2H)-dione, 6-amino-2-(2,4-dimethylphenyl)-

This is 6-amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione. Its chemical properties are as follows:
This compound contains amino, dimethylphenyl and benzoisoquinoline dione structural units. From a structural point of view, amino groups are alkaline to a certain extent, and can bind protons because nitrogen atoms have lone pairs of electrons. In a suitable acidic environment, amino groups are easily protonated, which in turn affects the overall charge distribution and solubility of the compound.
Dimethylphenyl is used as an aromatic hydrocarbon substituent to endow the compound with certain hydrophobicity. The π-electron system of phenyl groups makes the compound have a certain conjugation effect, which affects its electron cloud distribution and spectral properties. The presence of two methyl groups increases the steric resistance, which has an impact on the reaction activity and the interaction between molecules. Methyl groups are the power supply subgroups, which can increase the electron cloud density of the benzene ring through the induction effect and the superconjugation effect, which affects the electrophilic substitution reaction activity on the benzene ring.
The structure of benzoisoquinoline dione part, the dione structure makes the region have a certain acidity. Due to the electron-withdrawing action of carbonyl groups, α-hydrogen has a certain acidity. It is easy to leave under the action of alkali, which triggers related reactions, such as enolization reaction, forming an enol structure with special reactivity, participating in nucleoph The whole benzisoquinoline framework has a rigid planar structure, which affects the molecular accumulation and crystal structure, and also plays a role in its physical properties such as melting point and solubility. And due to the existence of the conjugate system, the structure has characteristic absorption in the ultraviolet and visible regions, which can be used for spectral analysis and identification. Its chemical properties make it potentially used in organic synthesis, medicinal chemistry and other fields. It can be used as an intermediate for constructing more complex structures, or based on its structural modification to develop compounds with specific biological activities.

6-Amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione, which is widely used. In the field of medicine, it may be a key pharmaceutical intermediate. Due to its unique chemical structure, it can be derived from compounds with pharmacological activity through specific chemical reactions to fight a variety of diseases. For example, in the development of new anti-tumor drugs, the structure of this compound can be used as a basic framework, modified and modified to bind to specific targets in tumor cells, thereby inhibiting the growth and spread of tumor cells.
also has potential applications in the field of materials science. Due to its special molecular structure, it may endow materials with special optical and electrical properties. For example, through rational design and synthesis, materials with specific fluorescence properties may be prepared for use in optical sensors, Light Emitting Diodes and other devices to improve the performance and function of such devices.
Furthermore, in the field of organic synthesis, this compound can be used as an important starting material or intermediate. With its active groups such as amino groups and diketones, it can participate in many classical organic reactions, such as nucleophilic substitution, cyclization, etc., to construct more complex and diverse organic molecular structures, providing new avenues and possibilities for the development of organic synthesis chemistry. In conclusion, 6-amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione has shown important application value in many fields, and the prospect is quite promising.

To prepare 6-amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione, you can follow the following ancient method.
Take 2,4-dimethylbenzoic acid first, and heat it with thionyl chloride in an appropriate way to obtain 2,4-dimethylbenzoyl chloride. This step requires attention to the temperature and duration of the reaction to ensure that the reaction is sufficient and the device is well sealed to prevent the escape of harmful gases. < Br >
Then the obtained 2,4-dimethylbenzoyl chloride and ethyl anthranilate are added to a suitable organic solvent, such as toluene, with an appropriate amount of catalyst, such as triethylamine, and stirred at temperature. In this reaction, the proportion of materials, reaction temperature and stirring rate are all crucial, and fine regulation is required to enable the acylation reaction of the two to occur smoothly to obtain the corresponding intermediate product.
Subsequently, the obtained intermediate product is placed in a strong alkali environment, such as sodium hydroxide solution, and heated for hydrolysis. During the hydrolysis process, the reaction phenomenon should be closely observed, and the temperature and reaction time should be adjusted according to the progress of the reaction, so that the ester group can be hydrolyzed smoothly.
After hydrolysis is completed, it can be treated by acidification to precipitate a solid. The solid is recrystallized and purified many times to remove impurities and improve the purity of the product.
Finally, the purified product can be prepared by intramolecular cyclization under specific conditions, such as heating and adding an appropriate dehydrating agent, to obtain 6-amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione. After each step of the reaction, the product needs to be properly handled, or separated and purified, or stored for later use, and the operation of each step must be fine and accurate to obtain the ideal product.

I haven't heard the exact price of "1H + -Benz (de) isoquinoline -1,3 (2H) -dione, 6 -amino-2- (2,4 -dimethylphenyl) " in the market. This may be a rare chemical, and its price varies greatly due to quality, purity, and supply and demand.
If in the context of "Tiangong Kaiwu", although there is no such modern chemical thing, it can be deduced that its pricing is reasonable. In ancient times, the price of a thing often depended on the rarity of the material and the simplicity of the production. Today, if the raw materials of this chemical product are rare, difficult to collect, and the synthesis method is complicated, it requires exquisite skills and valuable utensils, and its price is high.
And if there is a large demand for this product and the supply is limited, the price will also rise. On the contrary, if the raw materials are easy to obtain, it is not difficult to make, and the market is oversupplied, the price will be cheaper.
However, I do not know the specific price range of this chemical in the current market conditions. If you want to know more about it, you can get a more accurate price range by consulting a chemical material dealer or a chemical product trading platform.

In order to know the safety and toxicity of 6-amino-2- (2,4-dimethylphenyl) -1H-benzo (de) isoquinoline-1,3 (2H) -dione, it is necessary to check all kinds of books in detail.
Looking at this compound, it is a product of organic synthesis, and the structure is slightly complicated. In general, substances containing such structures may pose potential risks. However, looking at its structure alone, it is difficult to determine the details.
To investigate the safety of this substance, it is necessary to check from multiple ends. First, check its preparation process, the raw materials, reagents and reaction conditions used, or have implications for its safety. If the raw material is toxic and harmful, and it is not completely transformed or removed during the reaction, the product or residue is toxic. Second, consider its chemical properties. The amino group, diketone and other groups contained in this compound may have a certain activity, in a specific environment, or react with other substances, resulting in toxic changes.
When it comes to toxicity, follow the scientific method. Animal experiments are required to observe its impact on animal physiology, behavior, organs, etc., to measure its acute toxicity, subacute toxicity, chronic toxicity, etc. It is also necessary to consider its toxicity to the environment, if it flows into nature, or what effects it has on ecosystems such as water, soil, and organisms.
Sadly, at this time I do not have detailed information, it is difficult to fully describe its safety and toxicity. However, those who seek to know this product should visit professional books, scientific research literature, or consult the experts of chemistry and toxicology to obtain its true meaning, in order to understand whether it is available in the fields of production, life, and scientific research, and how to avoid its harm and develop its strengths.