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What is the chemical structure of (1E) -1- [ (3,4-diethoxyphenyl) methylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
(1E) -1- [ (3,4 -diethoxybenzyl) acetyl] -6,7 -diethoxy-1,2,3,4 -tetrahydroisoquinoline formic anhydride, this is an organic compound. To understand its chemical structure, let me tell you in detail.
In this compound, the configuration of (1E) epitope double bond is E type. The 1-position is connected to a specific group, [ (3,4-diethoxybenzyl) acetyl], of which 3,4-diethoxybenzyl, that is, the phenyl ring of the benzyl group is connected to ethoxy at the 3,4-position; after the acetyl group is connected to the benzyl group, it is connected to the 1-position of the main structure as a whole. 6,7-diethoxy, showing that the 6 and 7 positions of the main structure are connected to ethoxy groups. 1,2,3,4-tetrahydroisoquinoline is the basic skeleton, and this skeleton is connected to formic anhydride.
In the ancient style of "Tiangong Kaiwu":
"There is a thing today, and its structure is very different. ( 1E) The configuration determines its double bond state, and the first position is connected to the (3,4-diethoxybenzyl) acetyl group, which is like an odd branch. The ethoxy group at positions 3 and 4 is embellished with the benzyl benzene ring. The ethoxy group at positions 6 and 7 adds a unique appearance to it. 1,2,3,4-tetrahydroisoquinoline is the bone, which is related to formic anhydride, resulting in this unique structure. This structure is seamless, and the parts are related to each other. It is unique in the field of organic. "
What are the physical properties of (1E) -1- [ (3,4-diethoxyphenyl) methylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
(1E) - 1 - [ (3,4-diethoxybenzyl) acetyl] - 6,7-diethoxy-1,2,3,4-tetrahydroisoquinolinone ketoate is a chemical substance. Its physical properties are as follows:
Looking at it, this substance often takes a specific form. Or in the form of crystals, white and pure, like snow falling at the beginning of winter, the texture is delicate and uniform, and under the light, it shines with a subtle and soft luster, as if it contains countless tiny stars.
Its melting point is also an important physical property. After careful determination, under certain conditions, when a certain precise temperature is reached, this substance slowly melts from the solid state to the liquid state. This temperature limit is clear, which is its inherent characteristic, just like the precise scale given by nature.
In terms of solubility, it shows different performance among many common solvents. In some organic solvents, such as alcohol solvents, it can be moderately dissolved, just like being integrated into it to form a uniform and stable system; in solvents such as water, the degree of solubility is quite limited, like a water-repellent leaf, which can only float on the surface and is difficult to truly blend.
In addition, its density also has a unique value. Placing this object in an accurate measuring instrument and measuring the ratio of its mass to volume, a specific value can be obtained. This value reflects the degree to which its molecules are closely arranged, just like the embodiment of the interaction between molecules in the microscopic world.
Furthermore, the boiling point of this object is also a key property. When enough heat is applied to reach a certain high temperature, the liquid boils, and a large number of bubbles gush out of the liquid and transform into a gaseous state. This boiling point temperature is stable and clear, providing an important basis for the identification and application of this substance.
Various physical properties are like a key to help us open the door to understanding this object, which is of crucial significance in many fields such as chemical research and industrial production.
What is the use of (1E) -1- [ (3,4-diethoxyphenyl) methylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride?
(1E) - 1 - [ (3,4 - diethoxybenzyl) acetyl] - 6,7 - diethoxy - 1,2,3,4 - tetrahydroisoquinoline benzoate, which is an organic compound, in the field of medical chemistry, often has unique medicinal value.
According to the "Tiangong Kaiji", the use of various substances depends on their characteristics. As far as this compound is concerned, it may be used for medical research and development. In modern medical research, organic compounds are often key elements in the creation of new drugs. Its structure contains diethoxybenzyl, acetyl and other groups, or gives this compound specific biological activity.
The combination of different groups can interact with specific targets in organisms. For example, in the drug development of nervous system diseases, the compound may use its unique structure to precisely act on neurotransmitter receptors or related enzymes, modulate nerve signaling, and achieve therapeutic purposes. Or in the field of cardiovascular diseases, it can act on specific ion channels on vascular smooth muscle cells, regulate vascular tension, and stabilize blood pressure.
Furthermore, in the drug synthesis process, this compound may act as an important intermediate. After a specific chemical reaction, other functional groups can be added to construct more complex drug molecules with specific therapeutic effects. In this way, with its unique structure, it can provide diverse possibilities for pharmaceutical research and development to meet the needs of human health.
What is the synthesis method of (1E) -1- [ (3,4-diethoxyphenyl) methylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride?
To prepare (1E) -1- [ (3,4-diethoxybenzyl) ethylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline benzoate, the following ancient method can be carried out.
First take the appropriate raw materials, and interact with the components in a specific reaction sequence and conditions. Initially, put the relevant reagents in a suitable reaction vessel in precise proportions. < Br >
First, the reactants containing specific groups, such as compounds with diethoxy benzyl structures, and reagents that can introduce ethylene groups, under appropriate catalysts and reaction temperatures, are condensed to form (3,4-diethoxy benzyl) ethylene structural units. This step requires strict control of the reaction temperature and time. If the temperature is too high, side reactions will easily occur, and if it is too low, the reaction rate will be too slow.
After obtaining this key intermediate, it will react with compounds containing 6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline structures. This reaction can be carried out in a specific organic solvent under appropriate alkali catalysis to combine the two to form a key skeleton.
Subsequently, the resulting product is esterified with benzoic acid reagents under suitable reaction conditions to introduce benzoate groups. During this process, attention should be paid to the pH, temperature and reaction time of the reaction system to ensure that the reaction proceeds smoothly in the direction of generating the target product.
After the reaction is completed, the impurities are removed through multiple processes such as separation and purification, and the final product is pure (1E) -1- [ (3,4-diethoxybenzyl) ethylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline benzoate. The whole process requires fine operation and strict control of each reaction parameter to obtain satisfactory yield and purity.
What are the safety precautions for (1E) -1- [ (3,4-diethoxyphenyl) methylene] -6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride?
(1E) - 1 - [ (3,4 - diethoxybenzyl) acetyl] - 6,7 - diethoxy - 1,2,3,4 - tetrahydroisoquinoline benzoate is a complex organic compound. The safety precautions for this compound are detailed as follows:
First, the inherent characteristics of chemical substances cannot be ignored. Such organic compounds may be flammable. When storing and using, it is necessary to keep away from fire and heat sources to avoid the risk of fire. And because of its complex structure, some functional groups or chemical activity, it is easy to react with other substances. Therefore, before mixing or contacting other chemicals, it is necessary to carefully consult relevant information to clarify their chemical properties and compatibility to avoid dangerous chemical reactions.
Second, the impact on human health also needs to be paid attention to. If the compound is accidentally exposed to the skin, it may cause skin irritation, redness, swelling, itching and other symptoms. Once such a situation occurs, it should be immediately rinsed with a lot of water, and then seek medical attention as appropriate. If it comes into contact with the eyes, the consequences are more serious, or cause eye burns. At this time, you need to immediately open the eyelids, rinse with flowing water for more than 15 minutes, and go to the ophthalmology department for treatment as soon as possible. If you inhale it inadvertently, or it irritates the respiratory tract, causing symptoms such as cough and asthma, you should quickly move to a place with fresh air. If the symptoms are not relieved, you must seek medical attention in time. In case of accidental ingestion, you need to seek medical attention immediately without delay.
Third, environmental considerations In the process of production, use and disposal of this compound, do not release it into the environment at will. Because of its complex structure or difficult to degrade, it causes pollution to environmental factors such as soil and water sources. Environmental protection regulations should be followed, and proper disposal methods should be adopted, such as handing over to professional waste treatment institutions for harmless treatment, in order to minimize the negative impact on the environment.
Fourth, storage and operation practices are also key points to ensure safety. When storing, it should be placed in a cool, dry and well-ventilated place, away from direct sunlight. At the same time, it should be stored separately from oxidants, acids, alkalis and other substances, and must not be mixed with storage and transportation. During the operation, the operator must wear appropriate protective equipment, such as protective gloves, protective glasses, gas masks, etc., to reduce the risk of contact. The operation site also needs to be equipped with corresponding fire equipment and leakage emergency treatment equipment, so that in the event of an emergency, it can respond quickly.