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What is the chemical structure of (13aS) -2, 3,9,10-tetramethoxy-5,8,13, 13a-tetrahydro-6H-isoquino [3,2-a] isoquinoline
(13aS) - 2,3,9,10 - tetramethoxy - 5,8,13,13a - tetrahydro - 6H - isoquinolo [3,2 - a] isoquinoline, this is an organic compound. Looking at its name, it can be seen that its structure contains isoquinolo [3,2 - a] isoquinoline The parent nuclear structure of isoquinoline. "13aS" shows that its three-dimensional configuration at the 13a position is S-type. "2,3,9,10 - tetramethoxy" indicates that there is a methoxy group (-OCH) at the 2, 3, 9, 10 positions of the parent nucleus. The introduction of this methoxy group affects the physical and chemical properties of the compound, such as polarity and solubility. " 5,8,13,13A-tetrahydro ", indicating that the unsaturated bonds at the 5, 8, 13, and 13a positions in the parent nucleus structure are hydrogenated to form saturated bonds, resulting in corresponding changes in the stability and reactivity of the molecule.
Its specific chemical structure is based on isoquinoline and [3,2-a] isoquinoline as the core, with methoxy and hydrogen atoms added at specific positions. This structure may give the compound unique biological activity and physicochemical properties, and may have potential applications in organic synthesis, medicinal chemistry, etc. For example, because it contains multiple methoxy groups, or has a certain lipid solubility, it is conducive to crossing biological membranes, and is used in drug development, or as a potential active ingredient.
What are the physical properties of (13aS) -2, 3,9,10-tetramethoxy-5,8,13, 13a-tetrahydro-6H-isoquino [3,2-a] isoquinoline
(13aS) - 2,3,9,10 - tetramethoxy - 5,8,13,13a - tetrahydro - 6H - isoquinoline [3,2 - a] isoquinoline This substance has various physical properties. Its properties are mostly crystalline, which is caused by the regular arrangement of intermolecular forces.
Looking at its melting point, it is about a specific temperature range, which is determined by the lattice energy, causing the crystal to be heated to a certain critical point, and the lattice structure begins to disintegrate. And its solubility is quite soluble in organic solvents such as ethanol and chloroform, because the molecules and solvent molecules can form van der Waals force or hydrogen bonds to enhance mutual affinity; however, it is insoluble in water, because its molecular structure is dominated by hydrophobic groups, and it has weak affinity with water molecules.
Furthermore, the density of this substance is fixed, depending on its molecular weight and the degree of packing compactness. In solution, it has a specific absorption of light, and at the ultraviolet-visible spectrum, there is a characteristic absorption peak, which is derived from the transition of electrons in the molecule and is related to the conjugate structure. Its physical properties are controlled by the molecular structure and composition, and have important guiding effects in many fields such as chemical research and drug development.
(13aS) -2, 3, 9, 10-tetramethoxy-5,8,13, 13a-tetrahydro-6H-isoquino [3,2-a] What is the main use of isoquinoline
(13aS) - 2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolo [3,2-a] isoquinoline is a class of organic compounds with special structures. In various fields, it shows its important use.
In the field of pharmaceutical research and development, its pharmacological activity has attracted much attention. Many studies have shown that such compounds may have anti-tumor effects. It can inhibit specific tumor cell lines by interfering with the proliferation of tumor cells and inducing apoptosis, providing key lead compounds for the creation of new anti-tumor drugs, and is expected to become a sharp edge to conquer cancer. < Br >
In the field of organic synthesis, its unique fused ring structure provides challenges and opportunities for synthetic chemists. The construction of its complex structure requires delicate synthesis strategies, such as the use of new catalytic reactions and selective functionalization. The process of synthesizing this compound can promote the progress of organic synthesis methodologies, help chemists master more efficient and accurate synthesis techniques, and pave the way for the creation of more complex and unique organic molecules.
In the field of materials science, appropriate modifications may endow it with special optoelectronic properties. It can be applied to the preparation of organic Light Emitting Diodes, solar cells and other materials. Through the relationship between its molecular structure and properties, new materials with excellent properties can be developed, injecting new vitality into the development of materials science and exploring new directions.
(13aS) - 2,3,9,10 - tetramethoxy - 5,8,13,13a - tetrahydro - 6H - isoquinolo [3,2 - a] isoquinoline has potential application value and research significance in many fields such as medicine, organic synthesis, and materials science. It is like a treasure to be discovered, attracting many researchers to explore and study.
What are the synthesis methods of (13aS) -2, 3,9,10-tetramethoxy-5,8,13, 13a-tetrahydro-6H-isoquino [3,2-a] isoquinoline
The synthesis method of (13aS) -2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino [3,2-a] isoquinoline, although the ancient book "Tiangong Kaiji" does not directly describe the synthesis method of such compounds, it contains technological wisdom, which may inspire ideas.
In ancient chemical processes, to obtain this compound, you can first find suitable starting materials. Or extract natural products with isoquinoline structure, such as some alkaloids containing such structures, which can be obtained by extraction and separation from plants. In the past, the extraction method, or using solvents such as wine and water, dissolves the target component according to the difference in solubility.
If the starting material is obtained, its structure can be modified by thinking. The introduction of tetramethoxy group can imitate the method of etherification by ancient people. Select the halogenated methane with suitable activity, and react with the phenolic hydroxyl group in the starting material under the catalysis of alkali. For alkalis, basic substances such as plant ash can be used. Although its alkalinity is slightly weaker, it can be reacted under mild conditions, or the phenolic hydroxyl can be gradually etherified, and finally the product of tetramethoxy modification can be obtained.
The structure formation of tetrahydrogen, or the method of hydrogenation can be tried. Although there is no high-pressure hydrogen equipment in ancient times, it is possible to find active hydrogen donors, such as hydrogen produced by the reaction of metals and acids, or some compounds with active hydrogen, in the presence of catalysts, to hydrogenate double bonds. Catalysts or natural minerals can be tried, such as some iron and copper-containing ores, with their catalytic activity, to promote hydrogenation reactions and construct tetrahydro structures.
After the above steps, (13aS) -2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolo [3,2-a] isoquinoline can be gradually synthesized. Although the conditions of ancient times were difficult to operate and the yield was low, the idea can be followed. With the wisdom of ancient times, the synthetic chemistry of today is inspired.
(13aS) -2, 3,9,10-tetramethoxy-5,8,13, 13a-tetrahydro-6H-isoquino [3,2-a] Is isoquinoline biologically active
(This is a question involving the names of complex organic compounds, which is related to whether they are biologically active. In ancient Chinese, the following answer is made.)
Looking at this (13aS) - 2,3,9,10 - tetramethoxy - 5,8,13,13a - tetrahydro - 6H - isoquinoline [3,2 - a] isoquinoline, its structure is exquisite and quite wonderful. However, whether it is biologically active is difficult to determine.
The existence or absence of biological activity of all kinds of organic things in the world often depends on the experience of many parties. Or try it on a living being, observe its impact on the body, and see if it can cause physiological changes, such as metabolic changes and functional adjustments; or test it in an isolated system, study its interaction with biological macromolecules, such as proteins and nucleic acids, and see if it can form bonds and cause conformational changes.
However, only in terms of this name, without involving the evidence of its experiment, I cannot say whether its biological activity is present or not. Only through rigorous scientific investigation, based on experiments, and data as evidence can we know whether it can play a unique role in biological systems and whether it has biological activity or not.