1 Isopropyl 2 Oxo 1 2 Dihydroquinoline 3 Carboxylicacid
quinoline thiophene imidazole thiazole

1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylicacid

Taiy Chemical

    Specifications

    HS Code

    698088

    Chemical Formula C13H13NO3
    Molar Mass 231.25 g/mol
    Appearance Solid
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents
    Stability Stable under normal conditions

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    General Information
    Where to Buy 1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylicacid in China?
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    Frequently Asked Questions

    As a leading 1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylicacid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 1-Isopropyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid?
    1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid, according to its name, its structure can be roughly analyzed. In this compound, the quinoline ring is its core structure. The quinoline ring is a nitrogen-containing heterocyclic ring formed by fusing the benzene ring with the pyridine ring.
    In the 1,2-dihydroquinoline part, it can be seen that the double bond between the 1,2 positions of the quinoline ring has been hydrogenated to form a single bond, so it is a dihydro state. And the 2-oxo generation shows that there is a carbonyl group connected to the 2 positions, and the oxygen atom is connected to the carbon by a double bond, which gives the molecule a specific chemical activity.
    Furthermore, 1-isopropyl indicates that the group attached to the 1-position carbon is isopropyl. The isopropyl group is a monovalent hydrocarbon group composed of three carbon atoms, which is branched like a branch.
    As for the 3-carboxylic acid, there is a carboxyl group at the 3rd position of the quinoline ring. The carboxyl group is formed by linking the carbonyl group to the hydroxyl group. The structure of -COOH makes it acidic and can participate in many chemical reactions. < Br >
    The structure of this compound is composed of quinoline ring as the base, supplemented by various substituents, and each part affects each other to jointly determine its chemical properties and reactivity. It may have important research value and application prospects in the fields of organic synthesis, medicinal chemistry, etc.
    What are the main physical properties of 1-Isopropyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid?
    1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid, this is an organic compound. Its physical properties are quite important, let me tell you in detail.
    Looking at its properties, under normal temperature and pressure, this compound is often in a solid state. As for the color, or white to white powder, the texture is fine, just like the frost and snow that falls at the beginning of winter, pure and uniform.
    When it comes to melting point, this is one of its key physical properties. After many experiments, its melting point is roughly within a certain range, but it will also change slightly due to slight differences in experimental conditions. The determination of the melting point is like exploring the key node of the transformation of this compound under the action of heat, and it is like a key to open the door to the mystery of its inherent properties.
    In terms of solubility, this compound behaves differently in different solvents. In organic solvents such as ethanol and acetone, it has a certain solubility, just like a fish entering water, it can blend with solvent molecules and disperse them; however, in water, its solubility is relatively poor, just like the incompatibility of oil and water. Most of them remain in the water in solid form, making it difficult to dance closely with water molecules.
    In addition, its density is also a physical property that cannot be ignored. Although the exact value needs to be accurately measured with the help of professional instruments, roughly speaking, its density gives this compound a unique relationship between mass and volume, which is of great significance in both practical application and theoretical research.
    In summary, the physical properties of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid, such as properties, color, melting point, solubility and density, are like a fine intertwined picture, which together depict the external physical appearance of this compound, laying the foundation for its research and application in many fields.
    Where is 1-Isopropyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid used?
    1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid is used in medicine, chemical industry and other fields.
    In the field of medicine, it is often the key intermediate for synthesizing drugs. Taking the development of antibacterial drugs as an example, with its unique chemical structure, it can introduce specific functional groups through a series of chemical reactions to construct compounds with high antibacterial activity. By interfering with bacterial cell walls, cell membranes or key metabolic pathways, it exhibits antibacterial effect and adds a sharp edge to the battle against bacterial infections in human beings.
    In the field of chemical industry, it also has a role in materials science. It can be used to prepare polymer materials with special properties, such as polymers with good thermal stability and mechanical properties. Because its structure contains specific aromatic rings and functional groups, it can play a unique role in the polymerization reaction, promoting the formation of a regular structure of the polymer, thereby improving the properties of the material. In the coating industry, it can be added as a modifier to the coating to enhance the adhesion and corrosion resistance of the coating, so that the coating can maintain a good state in different environments and protect the surface of the coated object.
    What are the synthesis methods of 1-Isopropyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid
    The synthesis method of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid has been investigated throughout the ages. In the past, many scholars worked hard in the field of organic synthesis and created many methods to prepare such compounds.
    One method is to use quinoline derivatives as starting materials. First take the appropriate quinoline and introduce the isopropyl group under specific reaction conditions. In this step, a suitable reagent and reaction environment need to be selected to ensure that the isopropyl group is precisely added to the specific position of the quinoline. The commonly used method, or the nucleophilic substitution reaction, uses a reagent containing isopropyl, such as isopropyl halide, to react with quinoline derivatives under the catalysis of alkali. The type and dosage of base, the reaction temperature and time are all key factors, and need to be carefully controlled to obtain the ideal yield and selectivity.
    After the introduction of isopropyl, the oxidation reaction is continued to construct a 2-oxo structure. For this oxidation step, strong oxidants such as potassium permanganate and potassium dichromate, or specific transition metal catalyzed oxidation systems can be selected. During the reaction, pay attention to the tolerance of the substrate to avoid damage to the product due to excessive oxidation.
    As for the construction of 3-carboxylic acid moiety, it can be achieved by carboxylation reaction on the basis of the above reaction. Or use carbon dioxide as the carboxyl source, and under the action of suitable metal catalysts and ligands, the substrate reacts with carbon dioxide to introduce carboxyl groups. In this process, the activity of the catalyst and the structure of the ligand have a great influence on the reaction process and results.
    There is another way, using o-amino benzoic acid derivatives as the starting material. First, the cyclization reaction is carried out to construct a quinoline skeleton. This cyclization reaction may require conditions such as high temperature and strong acid to promote the formation of intra-molecular rings. After cyclization, isopropyl and 2-oxo structures are introduced in turn. The methods for introducing isopropyl and constructing 2-oxo structures are similar to those described above, but the reaction details may vary due to different starting structures.
    In addition, there are strategies for gradually constructing target molecules by using other heterocyclic compounds as raw materials through multi-step transformation. Each method has its advantages and disadvantages, and it needs to be weighed according to actual needs, such as the availability of raw materials, the difficulty of the reaction, and the purity of the product.
    What is the market prospect of 1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid?
    1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid has considerable market prospects. Looking at the field of pharmaceutical chemical industry today, the research and development of innovative drugs is booming, and many new compounds have emerged, and this acid substance also plays a role in it.
    From a pharmaceutical point of view, it may have unique pharmacological activities and can be used as an intermediate for drug development. The creation of many new anti-cancer, anti-inflammatory and other drugs often relies on such nitrogen-containing heterocyclic carboxylic acid compounds as the basic framework. Due to its special molecular structure, it can be combined with specific targets in organisms to exert pharmacological effects. Therefore, in the pharmaceutical synthesis industry chain, its demand may be on the rise.
    In the chemical industry, there is also a potential demand for it in the paint and dye industries. With its structural characteristics, it can be chemically modified to give products special properties, such as improving the light resistance of dyes and the adhesion of coatings.
    Furthermore, with the deep penetration of the concept of green chemistry, if this compound can be synthesized in an environmentally friendly process, it will be able to meet the market's pursuit of sustainable products. Although the current market may not have reached its peak state, over time, with the deepening of research and the expansion of application fields, its market prospects are expected to bloom gradually, playing a more critical role in the pharmaceutical and chemical industries, attracting more manufacturers and researchers to participate in it and promote its development.