1 Ethyl 6 7 Methylenedioxo 4 Quinoline 3 Carboxlicacid
quinoline thiophene imidazole thiazole

1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid

Taiy Chemical

    Specifications

    HS Code

    707456

    Chemical Formula C15H13NO5
    Molar Mass 287.27 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point Specific value would require experimental determination
    Solubility In Water Low solubility, being an organic acid
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Acidity It is a carboxylic acid, so it can donate a proton, has an acidic hydrogen on the -COOH group
    Stability Stable under normal conditions but may decompose under extreme heat or in the presence of strong oxidizing agents
    Uv Vis Absorption Absorbs in the ultraviolet - visible region due to the conjugated system in the quinoline ring

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxlic acid?
    1 + - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxylic acid is 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxylic acid. The following classical Chinese form is used to describe its chemical structure:
    This compound belongs to quinoline carboxylic acids. Quinoline is a nitrogen-containing heterocyclic aromatic hydrocarbon, with a benzene ring fused with a pyridine ring. Among its structures, the quinoline ring is the backbone, such as the pillar of a building, and its fundamental structure is determined. < Br >
    At the 4th position, it is connected with a carboxyl group (-COOH). The carboxyl group is like a flexible feather, giving compounds the sign of acidity and can participate in many chemical reactions. It is like an elite in the army, with extraordinary combat power.
    Between the 6th and 7th positions, there is a methylene dioxy group (-OCH 2O O -) connected. This methylene dioxy group is like a delicate bridge, spanning the atoms at the 6th and 7th positions, forming a unique structure. Due to its existence, the density of the electron cloud in this area changes, affecting the physical and chemical properties of the compounds, and also affecting the trend of the war.
    Above the 1 position, ethyl (-C ² H) is connected, and ethyl extends like branches, adding hydrophobicity to the whole molecule, affecting its solubility and spatial steric resistance, just like adding a channel next to the building, changing the interaction between molecules.
    Such various structural characteristics, synergistic effect, create the unique chemical properties and reactivity of 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid, which may play an important role in organic synthesis, pharmaceutical chemistry and other fields.
    What are the main physical properties of 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxlic acid?
    1 + - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxylic acid (1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxylic acid) is an important substance in the field of organic compounds. It has several key physical properties. The following are detailed by Jun:
    - ** Appearance properties **: This compound is often white to light yellow crystalline powder. Just like the ancient books said "colored frost and snow, shaped like powder chips", its powder has a fine texture and a certain luster. This appearance property is of great significance in identifying and preliminarily judging its purity. < Br > - ** Melting point **: The melting point of this substance is about 250-255 ° C. Just like the ancient alchemy, the temperature of the heat is strictly controlled, and the melting point of the substance is also a key feature. This specific melting point range, like its "identity brand", lays the foundation for accurate identification and quality control. Experimenters can determine the purity and authenticity of the compound according to the melting point.
    - ** Solubility **: 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid is slightly soluble in water, but soluble in common organic solvents such as ethanol, dichloromethane, etc. This difference in solubility is like a distinction between things, and can be skillfully exploited in the extraction, separation and synthesis process steps. Such as the ancient "water and oil phase separation", according to the different solubility, the efficient separation and purification of compounds can be achieved, which has far-reaching impact on their preparation and application.
    - ** Stability **: Under conventional storage conditions, this compound is generally stable. However, it needs to be stored in a cool place away from light, because light and high temperature may cause it to decompose or deteriorate, just like ancient objects are afraid of exposure to hot sun and wind. In a dry environment, its stability is better, and adverse changes such as high humidity or moisture dissolution should be paid attention to when storing and using.
    What are the common synthesis methods of 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxlic acid?
    1 + -Ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid, this is an important class of organic compounds, which is of great significance in the fields of medicinal chemistry. Its common synthesis methods are as follows:
    The selection and preparation of starting materials is very important. Usually aromatic compounds with specific substituents are used as starting materials, such as benzene ring derivatives containing suitable substituents. This starting material requires multiple steps of delicate transformation before the complex structure of the target molecule can be gradually constructed.
    One is a nucleophilic substitution reaction. Under specific reaction conditions, nucleophilic substitution occurs at specific positions of the starting material and nucleophilic reagents. The activity of the nucleophilic reagent and the activity of the reaction check point need to be precisely matched, so that the reaction can be carried out efficiently and with high selectivity. For example, the appropriate halogenated aromatics and nucleophilic reagents are selected to undergo nucleophilic substitution under alkali catalysis, which lays the foundation for the subsequent construction of quinoline rings.
    The second is the cyclization reaction. After nucleophilic substitution and other steps, the intermediate product can be formed by cyclization reaction to construct a quinoline ring structure. This process requires suitable reaction conditions, such as specific temperature and catalyst. Catalyzed by a suitable catalyst, the intermediate product is cyclized within the molecule to form a quinoline ring parent nucleus. This cyclization reaction is extremely sensitive to reaction conditions, and factors such as temperature and catalyst dosage will significantly affect the reaction yield and selectivity.
    The third is the introduction of substituents. After the formation of the quinoline ring, ethyl, methylene dioxy and other substituents need to be introduced at specific positions. This process is often assisted by organometallic reagents. For example, Grignard reagent or lithium reagent is used to react with specific positions on the quinoline ring to introduce alkyl substituents such as ethyl. When introducing methylene dioxy groups, methylene dioxy-containing structural units are often introduced into molecules through specific condensation reactions. This step also requires strict control of the reaction conditions to ensure the precise introduction of substituents.
    The fourth is oxidation and carboxylation. In some synthesis routes, intermediate products need to be oxidized to adjust the oxidation state of molecules, which is conducive to subsequent carboxylation reactions. The carboxylation reaction can be achieved by various methods, such as using carbon dioxide as the carboxyl source, introducing carboxyl groups at specific positions in the quinoline ring under suitable catalyst and reaction conditions, and finally generating 1-ethyl-6,7-methylene dioxy-4-quinoline-3-carboxylic acid.
    After each step of the reaction, the product needs to be separated and purified. Column chromatography, recrystallization and other methods are often used to obtain high-purity target products to ensure the quality of the products and the feasibility of subsequent research and application.
    Where is 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxlic acid used?
    1+-+ethyl+-+6%2C7+-+methylenedioxo+-+4+-+quinoline+-+3+-+carboxlic+acid that is, 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid, this compound has applications in pharmaceutical research and development, chemical synthesis and other fields.
    In the field of pharmaceutical research and development, it can be used as a key intermediate to create novel bioactive compounds. Because quinoline structure is common in many drugs, and the introduction of 6,7-methylenedioxy and 1-ethyl substituents may endow compounds with unique pharmacological properties. For example, antimicrobial drugs may be developed by modifying its structure. Quinoline antibacterial drugs are known for their strong inhibitory activity against a variety of bacteria. The structure of this compound may be adjusted and optimized to enhance the antibacterial efficacy against specific pathogens, opening up new paths for the creation of antibacterial drugs. Or anti-inflammatory active drugs can be developed, which can play an anti-inflammatory role by regulating the body's inflammation-related signaling pathways, providing new options for the treatment of inflammatory diseases.
    In the context of chemical synthesis, it can be used as a cornerstone for the construction of complex organic molecules. Because its structure contains a quinoline skeleton and specific substituents, it can participate in a variety of organic reactions. For example, it can be esterified and combined with alcohols to generate corresponding ester derivatives. Such esters may be used in flavors, coatings and other industries to give products a unique aroma or improve coating properties. It can also react with different nucleophiles through nucleophilic substitution reactions to expand the molecular structure and synthesize materials with special functions, such as for optical materials, so that the materials have unique optical properties, or for polymer materials to improve the mechanical properties and stability of polymer materials.
    What is the market outlook for 1 - ethyl - 6,7 - methylenedioxo - 4 - quinoline - 3 - carboxlic acid?
    1+-+ethyl+-+6%2C7+-+methylenedioxo+-+4+-+quinoline+-+3+-+carboxlic+acid is 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid, which is an organic compound and has important applications in the field of medicinal chemistry, especially the development of quinoline drugs. Its market prospects are detailed as follows:
    ###1. Pharmaceutical R & D drives demand growth
    Today, the pharmaceutical industry has never stopped exploring new antibacterial, anti-inflammatory and anti-cancer drugs. The unique chemical structure of 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid makes it potentially biologically active. In the field of antimicrobial drug research and development, scientists hope to obtain new drugs with high antibacterial properties and low drug resistance by modifying the structure of the compound. For example, the problem of drug-resistant bacteria has become more and more serious in recent years, and the demand for new antibacterial drugs is eager. This compound may provide a new idea for solving the problem of drug-resistant bacteria, so the market potential in the field of antimicrobial drug research and development is huge. In the research and development of anticancer drugs, studies have shown that quinoline compounds have a certain inhibitory effect on the growth of cancer cells. 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acids, as quinoline derivatives, may have unique anticancer activities, attracting the attention of many pharmaceutical companies and scientific research institutions, which is expected to give birth to new anticancer drugs, and then open
    ###Second, chemical synthesis raw materials are widely used
    in the chemical industry, 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid can be used as an important synthetic raw material. It can be used to prepare a variety of functional materials, such as organic materials with special optical and electrical properties. With the rapid development of electronic technology, the demand for high-performance organic materials is increasing day by day. Organic materials prepared from this compound may emerge in the fields of organic Light Emitting Diode (OLED) and solar cells. OLED displays are widely used in mobile phones, TVs and other electronic products due to their lightness, energy saving and high contrast. If 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid can help develop better OLED materials, its market demand will grow explosively. In the field of solar cells, improving the photoelectric conversion efficiency is the core goal. This compound may contribute to the development of new high-efficiency solar cell materials, thus expanding the application in the new energy materials market.
    ###III. Challenges and opportunities coexist
    Although the 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid market has broad prospects, it also faces many challenges. First, its synthesis process may be complex and costly. To achieve large-scale industrial production, it is necessary to optimize the synthesis process, reduce production costs and enhance product competitiveness. Secondly, the research and development cycle of new drugs is long, the investment is huge and the risk is high. From compound activity research to clinical trials, and then to approval for marketing, it needs to go through many links, and setbacks in any link may lead to R & D failure. However, opportunities and challenges coexist. With the continuous advancement of science and technology, the optimization of synthesis processes may be realized; the innovation of pharmaceutical research and development technology is also expected to accelerate the development of new drugs. And with the increasing emphasis on health and the growing demand for high-performance materials, as long as the problem can be overcome, 1-ethyl-6,7-methylenedioxy-4-quinoline-3-carboxylic acid will occupy an important place in the market and show great market value.