Chemical Name | 1-Cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride |
Molecular Formula | C20H23ClFN3O4 |
Molecular Weight | 423.87 |
Appearance | Solid (predicted) |
Melting Point | No data available |
Boiling Point | No data available |
Pka | No data available |
Logp | No data available |
1-Cyclopropyl-8-fluoro-6-methoxy-1, 4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-3-quinolinecarboxylic acid hydrochloride
This is the name of 1-cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolio [3,4-b] pyridine-6-yl] -4-oxo-3-quinoline carboxylic acid hydrochloride. To clarify its chemical structure, let me tell you in detail.
This compound belongs to the quinoline carboxylic acid class. The quinoline ring is its core structure, with a carboxyl group at the 3 position and a carbonyl group at the 4 position, which are common functional groups of quinoline carboxylic acids. The 1 position is connected to the cyclopropyl group, which can affect the spatial structure of the molecule and the distribution of electron clouds, and has an important impact on the activity of compounds. The introduction of fluorine atoms at the 8 position has a large electronegativity, which can change the molecular polarity and metabolic stability. Methoxy at the 6 position can increase the lipophilicity of molecules and affect their transmembrane transport and other properties.
The structure of [ (4aS, 7aS) -octahydro-6H-pyrrolio [3,4-b] pyridine-6-yl] connected to the 7th position has a unique spatial conformation and alkalinity, which has a profound impact on the binding of compounds to targets and pharmacological activities. The whole molecule exhibits specific physicochemical properties and biological activities due to the interaction of each group. In the form of hydrochloride, the compound forms a salt with hydrochloric acid, which can improve its solubility and stability.
In summary, the chemical structure of this compound is composed of a quinoline ring as the core and connects multiple unique groups. Each part works together to determine its chemical and biological properties.
1-Cyclopropyl-8-fluoro-6-methoxy-1, 4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-3-quinolinecarboxylic acid hydrochloride
1-Cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-3-quinolinocarboxylic acid hydrochloride, which is a chemical substance. Its main uses are quite extensive and its effectiveness is significant in the field of medicine.
It plays a key role in the development of antibacterial drugs. Due to its structural properties, it has the ability to inhibit and kill many bacteria. For example, it has effects on both Gram-positive and Gram-negative bacteria, and can effectively intervene in the physiological process of bacteria, such as hindering the function of bacterial DNA gyrase, which in turn affects the replication and repair of bacterial DNA, and eventually causes bacterial death. It can be used to treat a variety of diseases caused by bacterial infections, such as respiratory tract infections, such as pneumonia, bronchitis, etc., as well as urinary system infections, such as cystitis, pyelonephritis, etc.
In addition, it is also an important research object in the study of new antibacterial strategies. By analyzing the interaction mechanism with bacterial targets, researchers hope to develop more potent, more targeted and less side effects antibacterial drugs. Modify and modify its structure, explore the optimization direction, and promote the continuous development of antimicrobial drugs to deal with the increasingly serious problem of bacterial resistance.
1-Cyclopropyl-8-fluoro-6-methoxy-1, 4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-3-quinolinecarboxylic acid hydrochloride
1-Cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-3-quinolinocarboxylic acid hydrochloride, this drug is related to the safety of life, and its safety cannot be ignored.
Looking at its pharmacology, although it can cure diseases, it also has potential dangers. During clinical trials, doctors carefully observe the condition of the subjects. Some people take it, or have gastrointestinal discomfort, such as abdominal pain and diarrhea, which is the reason why the drug is in contact with the stomach. Some people feel dizzy, which may be due to the drug entering the blood and disturbing the clearing of the orifice.
Furthermore, long-term use of this drug also affects the organs of the liver and kidney. Liver and kidney, the main detoxification and excretion, the components of the drug accumulate in the body for a long time, or cause damage to its function. Therefore, those who use the drug should regularly check the ability of the liver and kidney to detect its changes.
And this drug needs to be used cautiously in special groups, such as pregnant women, the elderly and the weak. The body of pregnant women is related to the fetal essence, and the nature of the drug may be passed on to the fetus, causing its development to be biased. In the old and weak, the viscera are gradually declining, and the tolerance of the medicine is not as good as that of the young and strong. The dosage and course of treatment should be considered.
Those who use this medicine must follow the doctor's advice and do not change the dose or duration without authorization. If there is any discomfort, please tell the doctor immediately for treatment, so as to ensure the safety of the medication and achieve the effect of curing the disease.
1-Cyclopropyl-8-fluoro-6-methoxy-1, 4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-3-quinolinecarboxylic acid hydrochloride
1-Cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-3-quinoline carboxylic acid hydrochloride, according to its name, can be known as a chemically synthesized organic compound. Such compounds are mostly derived from modern chemical and pharmaceutical techniques and are not common in nature.
Looking at the current pharmaceutical market, if this compound is a new drug ingredient, its market prospect may be related to many factors. From the perspective of the disease field, if the disease it targets is a common and difficult disease, such as some complex infectious diseases, and the efficacy of existing drugs is not ideal, it may have a broad market. Both doctors and patients hope that new therapies will be released to relieve the pain of the disease.
However, when a new drug enters the market, it must go through many barriers. Pharmacological research needs to show that its efficacy is accurate and the side effects are minor. Clinical trials are also key, and multi-stage trials are conducted to prove its safety and effectiveness. Furthermore, market competition should not be underestimated. If there are many mature drugs for similar diseases, this compound needs to have unique advantages, such as better efficacy and ease of taking.
In terms of production, the difficulty of the synthetic process is related to the cost. If the process is complicated and the cost remains high, it will also affect its marketing activities. Sales strategy is also essential. Accurate positioning of the target doctor-patient group and strong publicity can make the product known to everyone. Therefore, its market prospect is like seeing flowers in the fog. Although there is hope, it is also full of thorns. Whether it succeeds or fails, there are still many efforts and opportunities.
1-Cyclopropyl-8-fluoro-6-methoxy-1, 4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-3-quinolinecarboxylic acid hydrochloride
1-Cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-3-quinoline carboxylic acid hydrochloride, which is a complex organic compound. Its production process is quite exquisite. When it is discussed by ancient methods, it is just like the exploration of ancient pharmaceuticals, which requires multiple exquisite processes.
Bear the brunt of the selection and preparation of raw materials. Select several pure and quality raw materials, which is the cornerstone of good products. Raw materials are like stars and moons, each performing its own role in the process according to its own characteristics.
Then, step into the journey of reaction. In a special reaction vessel, with precise heat and duration, the raw materials are blended and reacted with each other. This process is like a delicate chemical reaction dance, each raw material dances under specific conditions, and gradually generates the precursor of the target product according to the predetermined trajectory.
During the reaction process, the control of conditions is crucial. The level of temperature, just like the drumbeat of the reaction rhythm of the palm, or exciting or soothing, all affect the purity and yield of the product. The reaction time, just like the rhythm of the movement, can cause the product to change.
After the reaction is completed, the product is initially formed, but it still needs to be purified and refined. This step is like a craftsman carving beautiful jade to remove impurities and make the product pure and flawless. Or use the method of extraction, such as liquid-liquid extraction, to toss the product between different solvents and discard its dross; or by recrystallization, in a suitable solvent, let the product precipitate in a pure crystalline state.
Finally, after drying and other processes, the product is presented in a solid state and becomes 1-cyclopropyl-8-fluoro-6-methoxy-1,4-dihydro-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-3-quinoline carboxylic acid hydrochloride finished product. Each step requires rigorous operation. With a little carelessness, all previous efforts may be wasted. Only in this way can qualified products be prepared.