1 Cyclopropyl 6 Fluoro 8 Methoxy 7 4as 7as Octahydro 6h Pyrrolo 3 4 B Pyridin 6 Yl 4 Oxo 1 4 Dihydroquinoline 3 Carboxylic Acid Hydrochloride 1 1
Quinoline Thiophene Imidazole Thiazole
1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)
Chemical Name 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)
FAQ

What is the chemical structure of 1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)?

This is the chemical structure description of 1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolio [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1). This compound belongs to quinoline carboxylic acid derivatives. Its core structure is dihydroquinoline, which is connected with cyclopropyl at the 1st position, fluorine-containing atom at the 6th position, methoxy at the 8th position, carbonyl at the 4th position, and carboxyl at the 3rd position. Particularly critical, it is connected at the 7th position [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl], which is modified from the pyrrolido-pyridine ring system by octahydro saturation, and has a specific stereo configuration at the 4a and 7a positions. The hydrochloric acid salt form indicates that the compound is salted in a 1:1 ratio with hydrochloric acid. This chemical structure has a profound effect on its pharmacological activity, physicochemical properties and pharmacokinetic behavior.

What are the main uses of 1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)?

1-Cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrroso [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1), this is the name of the chemical substance, which is very important in the field of medicine.

This substance is often used as a key component of antibacterial drugs. Because it has a specific chemical structure, it can interfere with the key metabolic process of bacteria and inhibit the growth and reproduction of bacteria. Specifically, it can be combined with specific targets in bacteria to hinder the synthesis of bacterial nucleic acids or the assembly of proteins, and then achieve antibacterial effect.

In clinical terms, it is mostly used to treat infections caused by a variety of bacteria, such as respiratory tract infections, including pneumonia, bronchitis, etc.; also used for urinary system infections, such as cystitis, pyelonephritis, etc. In addition, it is also effective for skin and soft tissue infections. With its unique antibacterial mechanism and good antibacterial activity, it provides a powerful means for the treatment of many infectious diseases, plays an important role in maintaining people's health, and has become a class of compounds that have attracted much attention in pharmaceutical research and development and clinical treatment.

What are the side effects of 1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-1, 4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)?

1-Cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1), although this drug has significant efficacy, it also has various side effects.

Looking at its disturbance to the stomach and intestines, many users often feel abdominal discomfort after taking the medicine, or see nausea and vomiting, and even vomiting, and there is no lack of abdominal pain and diarrhea. This is because the drug stimulates the gastrointestinal mucosa, causing gastrointestinal transportation and loss of division, and poor qi.

It also affects the central nervous system. After taking the drug, some people may experience dizziness, like being in clouds and fog, walking unsteadily; or insomnia, insomnia, tossing and turning at night. Because the drug passes through the blood-brain barrier, it interferes with the transmission and regulation of neurotransmitters, causing neurological disorders.

In addition, it also has side effects on the skin, or the rash appears, the itching is intolerable, and the redness and swelling become more and more after scratching. This is caused by the body's allergic reaction to the drug, the loss of qi and blood, and the skin's pathology and pathology.

And this drug also has potential threats to liver and kidney function. Long-term or large-scale use can cause liver enzymes to increase, the metabolic burden of the kidneys to increase, and affect the body's normal detoxification and metabolic functions. Therefore, when taking medication, carefully weigh the pros and cons, pay close attention to changes in the body, and follow the doctor's instructions to prevent side effects.

1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)?

1-Cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrroso [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1), this is a rather complex organic compound. Its synthesis method is based on ancient techniques, or follows the path of multi-step reaction.

Initially, it may be necessary to carefully select raw materials containing specific groups such as cyclopropyl, fluorine, and methoxy, and combine them with conditions in an appropriate order. When constructing the core structure of quinoline, many techniques such as condensation reaction and cyclization reaction may be skillfully used. To introduce this part of [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl], specific modifications and modifications of the pyridine ring may be required, during which hydrogenation reactions may be involved to form the structure of octahydro, and precise control of stereochemistry is required to form the (4aS, 7aS) configuration.

When the key structure is initially formed, carboxyl groups are introduced and salted with hydrochloric acid. Each step of the reaction requires careful regulation of the reaction temperature, time, proportion of reactants, and the catalyst or reagent used to ensure that the reaction proceeds in the expected direction and improves the purity and yield of the product. Although the synthesis road is tortuous and complicated, with exquisite skills and a deep understanding of the reaction mechanism, the goal can be gradually achieved to obtain this compound.

1-cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolo [3,4-b] pyridin-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1) market outlook?

1-Cyclopropyl-6-fluoro-8-methoxy-7- [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1), which is a key compound in the field of medicinal chemistry.

Looking at its market prospects, the demand for antibacterial drugs has been increasing in recent years. As a key component of new antibacterial drugs, this compound may welcome broad opportunities. Due to the increasing bacterial resistance and the limited efficacy of traditional antibacterial drugs, the research and development of new antibacterial ingredients is imminent. Its unique chemical structure or endowed with a special antibacterial mechanism is expected to break the problem of drug resistance.

At the research and development level, researchers have poured a lot of effort into exploring its antibacterial activity, mechanism of action and pharmacokinetic properties. Some research results have initially shown a positive trend. If the follow-up clinical trials go well, it may be able to occupy a place in the antibacterial drug market after being approved for marketing.

However, it also faces challenges. The road to new drug development is full of obstacles, and it needs to go through multiple rounds of rigorous clinical trials to ensure safety and effectiveness. And the market competition is fierce, and there are many similar antibacterial drugs. If you want to stand out, you need to have unique advantages in terms of efficacy, safety or cost-effectiveness.

Despite the challenges, in view of the demand for and progress in the development of antimicrobial drugs, 1-cyclopropyl-6-fluoro-8-methoxy-7 - [ (4aS, 7aS) -octahydro-6H-pyrrolido [3,4-b] pyridine-6-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1) has a promising future and is expected to bring new opportunities for antimicrobial therapy.