1-cyclopropyl-6-fluoro-7- [ (1s, 4s) -5-methyl-2,5-diazabicyclo [2.2.1] hept-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate what is the chemical structure?

This is the chemical nomenclature of 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate. To clarify its chemical structure, it is necessary to analyze its chemical rules and naming conventions.

Looking at this designation, "1-cyclopropyl" indicates that the cyclopropyl group is attached to the first place of the parent nucleus; "6-fluorine", the epifluorine atom is in the sixth position of the parent nucleus; "7 - [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-group]", this part is the complex substituent, (1S, 4S) chiral configuration, "5-methyl" refers to the 5-position of the dicyclo structure with methyl, "2,5-diazabicyclo [2.2.1] heptyl-2-group" describes the dicyclo structure and the position of the nitrogen atom Number. " 4-Oxo-1,4-dihydroquinoline-3-carboxylic acid ", revealing that the parent nucleus is a dihydroquinoline structure, with an aerobic group at the 4th position and a carboxyl group at the 3rd position." Mono-methylsulfonate ", indicating that this compound forms salts with methanesulfonic acid.

Overall, its chemical structure is dihydroquinoline as the parent nucleus, which is connected with cyclopropyl, fluorine atoms, chiral-containing complex dicyclic substituents and carboxyl groups at specific positions, and forms methylsulfonates. Its parent nucleus, dihydroquinoline, has a conjugated system, which affects the stability and reactivity of compounds. Each substituent also plays an important role in the properties of compounds due to electronic and spatial effects. Cyclopropyl and fluorine atoms may change the lipophilicity and electron cloud distribution of the compound; contain chiral dicyclic substituents, or affect their binding specificity with biological targets; carboxyl groups and methanesulfonate parts are related to the water solubility and acidity of the compound.

What are the main uses of 1-cyclopropyl-6-fluoro-7- [ (1s, 4s) -5-methyl-2,5-diazabicyclo [2.2.1] hept-2-yl] -4-oxo-1, 4-dihydroquinoline-3-carboxylic acid monomethanesulfonate?

1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate, which is a rather complex chemical substance. Its main use is related to the field of medicine and is mostly used as an antibacterial drug.

This compound can effectively interfere with the DNA replication, transcription and repair process of bacteria by inhibiting the DNA rotatase and topoisomerase IV of bacteria, and then exhibit strong antibacterial activity. Its antibacterial spectrum is broad, and it has significant inhibitory and killing effects on many bacteria such as Gram-positive bacteria, Gram-negative bacteria and atypical pathogens.

In the field of clinical medicine, it is often used to treat respiratory tract infections, such as pneumonia, bronchitis, etc.; it is also used to treat urinary system infections, such as urethritis, cystitis, etc.; it also has a good therapeutic effect on skin and soft tissue infections, intestinal infections and other diseases. Due to its excellent antibacterial properties, it can effectively relieve the symptoms of patients and promote physical recovery, playing a crucial role in the process of human resistance to bacterial infections.

1-cyclopropyl-6-fluoro-7- [ (1s, 4s) -5-methyl-2,5-diazabicyclo [2.2.1] hept-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate What is the production process?

The production process of 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate is a crucial skill in the pharmaceutical field. The process is exquisite, and it needs to go through many steps and strictly control all links to achieve this drug.

At the beginning, when carefully selecting high-quality raw materials, the purity and quality of each raw material are related to the quality of the final product. If the raw material is established, it will enter the reaction process. The first step is usually a specific chemical reaction. In a suitable reaction vessel, the raw materials are mixed according to the precise ratio. At this time, temperature, pressure, and reaction time are all key elements and need to be carefully regulated. If the temperature is too high, it may cause overreaction and the product is impure; if the temperature is too low, the reaction will be delayed, which will affect the efficiency.

After the first step of reaction is completed, the product may need to be separated and purified. It can be filtered, extracted, distilled, etc., to remove its impurities and retain its essence to obtain a pure intermediate product. Then, this intermediate product enters a new round of reaction, or new reagents are introduced, and its molecular structure is gradually transformed into the target product according to the established reaction path.

After each step of the reaction, the purity and structure of the product must be carefully tested. Modern analytical techniques, such as nuclear magnetic resonance, mass spectrometry, etc., play a key role in this to confirm whether the reaction proceeds as expected and whether the product meets the requirements. If there is any deviation, the process parameters need to be adjusted in time.

After multi-step reaction and purification, the crude 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate is finally obtained. However, it still needs to be further refined to meet the medicinal standard. The refining process involves recrystallization, chromatographic separation, etc., so that the purity of the product is higher and the quality is better, and the final product can be used in pharmaceuticals and bring good news to patients. The entire production process is interconnected and cannot tolerate any sloppiness. Only with exquisite skills and rigorous attitude can pharmaceutical craftsmen create high-quality medicines.

1-cyclopropyl-6-fluoro-7- [ (1s, 4s) -5-methyl-2,5-diazabicyclo [2.2.1] hept-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate?

1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate, which is a promising compound, but its market prospects need to be examined in detail from various angles.

Looking at its pharmacological properties, this compound may have unique curative effects in the treatment of specific diseases, and can play a role in some difficult diseases, bringing new opportunities to the field of medicine. However, the competition in the pharmaceutical market is extremely fierce, and many similar drugs have already occupied the market. It is not easy to emerge in the meantime.

From the research and development process, if it has gone through many clinical trials, and the results are satisfactory, and it has been recognized by regulatory agencies, it can be successfully listed. However, the road to research and development is full of thorns, huge investment, time-consuming, and many uncertainties may cause R & D setbacks, which will affect its market advancement.

When it comes to market demand, if the number of patients with the targeted disease is large and the existing treatment methods are limited, this compound may welcome a broad market. However, if the disease is rare, the audience is limited, and the market scale will be limited.

Furthermore, production costs are also key. If the production process is complicated, the raw materials are scarce and expensive, and the product price may remain high, it will affect the market acceptance. Only by optimizing the production process and reducing costs can we improve our competitiveness.

In addition, marketing strategies are also indispensable. It is necessary to accurately target the target audience and let medical institutions and patients know its advantages through effective promotion.

In summary, 1-cyclopropyl-6-fluoro-7 - [ (1S, 4S) -5 -methyl-2,5 -diazabicyclo [2.2.1] heptyl-2-yl] - 4 -oxo-1,4 -dihydroquinoline-3 -carboxylic acid monomethanesulfonate market prospects, although there are opportunities, but also face many challenges, need to be properly addressed in R & D, production, marketing activities and other aspects, is expected to occupy a place in the market.

1-cyclopropyl-6-fluoro-7- [ (1s, 4s) -5-methyl-2,5-diazabicyclo [2.2.1] hept-2-yl] -4-oxo-1, 4-dihydroquinoline-3-carboxylic acid monomethanesulfonate What are the Quality Standards?

1-Cyclopropyl-6-fluoro-7- [ (1S, 4S) -5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] -4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate, this is the name of the chemical substance. Regarding its Quality Standard, it can be viewed from the following aspects:
- ** Properties **: Usually attention should be paid to its appearance, such as white to off-white crystalline powder, no impurities visible to the naked eye, uniform color is qualified. This is because the appearance is directly related to the purity of the substance and the initial quality impression.
- ** Identification **: First, infrared absorption spectroscopy can be used. The infrared spectrum of the substance should be consistent with the light spectrum of the reference substance, just like a human fingerprint. The infrared spectrum of each substance has unique characteristics, so that the identity can be identified. Second, using high-performance liquid chromatography, the retention time of its main peak should be consistent with the retention time of the main peak of the reference substance. This is also an important means to identify the substance.
- ** Related substances **: Using high-performance liquid chromatography for determination, the content of specific impurities shall not exceed the specified limit. If there are too many impurities, it may affect the purity and properties of the substance. For example, the main impurity content should not exceed 0.1% and the total impurity content should not exceed 0.5% to ensure the high purity of the substance. < Br > - ** Determination of content **: Determination by high performance liquid chromatography, calculated according to dry products, containing 1-cyclopropyl-6-fluoro-7- [ (1S, 4S) - 5-methyl-2,5-diazabicyclo [2.2.1] heptyl-2-yl] - 4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate shall not be less than 98.5%, which is a key indicator for measuring the amount of active ingredients of the substance. < Br > - ** Drying weight loss **: Take an appropriate amount of the substance and dry it under specified conditions. The weight reduction shall not exceed a certain limit, if not more than 0.5%, this is to control the moisture content in the substance. Excessive moisture or affect the stability and performance of the substance.
- ** Burning residue **: According to the law, the residual residue shall not exceed the specified limit, if not more than 0.1%, in order to consider the content of inorganic impurities in the substance.