1-Chloro-4-Methylisoquinoline

There is no exact record of "1+-+%E6%B0%AF+-+4+-+%E7%94%B2%E5%9F%BA%E5%BC%82%E5%96%B9%E5%95%89" in "Tiangong Kaiwu", but it is speculated that what you want to ask may be related to the use of similar substances containing "mercury (mercury) " and "methyl isobutyl ketone". Mercury was widely used in ancient times:
First, it was used for alchemy. The ancients believed that immortality could be achieved by refining medicinal pills. Mercury was often used as an important raw material for alchemy because of its unique chemical properties. For example, Ge Hong's "Baopuzi Interior" has many records of mercury alchemy. Alchemists mixed mercury with other minerals and went through complex refining processes to produce magical medicinal pills.
Second, it was used in the gilding process. This process requires mercury and gold to be made into gold amalgam, which is applied to the surface of metal utensils, heated to volatilize the mercury, and the gold is attached to the utensils to form a gilt layer, which enhances the appearance and anti-corrosion ability of the utensils. Many unearthed ancient gilt cultural relics are made by this method.
Third, it is also used in the field of medicine. Some ancient medical books believed that mercury could be used as medicine to treat scabies, sores and other diseases, but due to its strong toxicity, it should be used with caution.
Regarding the similar substances of "methyl isobutyl ketone", although there is no modern chemical concept of this substance in ancient times, there may be ingredients with similar chemical properties and functions in some natural plant or mineral extracts, or they may be used in some specific processes or folk therapies. However, due to the cognitive level at that time, it is difficult to have accurate scientific records and large-scale applications.

Alkanes are hydrocarbons with a general structural formula of\ (C_ {n} H_ {2n + 2}\). 1-Bromo-4-methylisophenene is an organic compound with unique physical properties.
It is mostly liquid at room temperature and pressure. Due to the moderate intermolecular force, it is not strong enough to solidify, and it is not weak enough to be easily vaporized. And it has a certain volatility. In an open environment, it can slowly escape into the air.
Looking at its solubility, it is insoluble in water. Because water is a polar solvent, and the polarity of 1-bromo-4-methyl isophenene is weak, according to the principle of "similar miscibility", the two are difficult to miscible. However, it can be soluble in many organic solvents, such as ethanol, ether, benzene, etc. Because organic solvents are mostly weakly polar or non-polar, they are compatible with the intermolecular force of the compound and are mutually soluble.
When it comes to density, it is smaller than water. If it is co-located with water, it can float on the water surface. This is determined by its molecular composition and structure. The mass of the substance contained in the unit volume is less than that of water.
The color state of 1-bromo-4-methylisophenene is usually colorless and transparent when it is pure, or very light when it contains few impurities, almost colorless. Because the molecular structure does not contain chromophores that can cause significant color, it absorbs visible light weakly.
In addition, it has a specific odor, but it is usually smelled by people, or it feels pungent and uncomfortable. This odor originates from the bromine atom and benzene ring in its molecular structure, which generate specific stimulation to olfactory receptors.

The chemical stability of 3-bromo-4-methyl isoprene depends on many factors and needs to be analyzed in detail.
In terms of its structure, the molecule contains carbon-carbon double bonds and bromine atoms. The carbon-carbon double bond has high reactivity because it is rich in electrons and is vulnerable to attack by electrophilic reagents. Common electrophilic addition reactions, the double bond of olefins can react with electrophilic reagents such as hydrogen halides and halogens. In this compound, the substituents around the double bond also affect its activity. The presence of methyl can increase the electron cloud density of the double bond due to the electron-giving induction effect, thereby enhancing its attraction to electrophilic reagents, resulting in more reactive double bonds, which reduces the stability of the compound to a certain extent.
Furthermore, the bromine atom is a halogen atom, which has a large electronegativity, and the carbon-bromine bond connected to the carbon atom has a certain polarity. Under appropriate conditions, the carbon-bromine bond can undergo heterocleavage, and the bromine atom leaves in the form of bromine ions, triggering nucleophilic substitution reactions. For example, in an alkaline environment, nucleophilic reagents such as hydroxyl negative ions can attack the carbon atom connected to the bromine and replace the bromine atom. This shows that the presence of bromine atoms also makes the molecular structure have a certain reactivity, which affects
However, the compound is not completely unstable. The overall structure of its molecule can maintain a certain stability if it is in a relatively mild environment without strong electrophilic reagents, nucleophiles, or special conditions such as high temperature and light. However, under suitable reaction conditions, its double bonds and bromine atoms can participate in the reaction, thus changing the molecular structure.
In summary, the chemical properties of 3-bromo-4-methyl isoprene are not absolutely stable, but relative. Under different environments and reaction conditions, its stability varies, and when appropriate reaction conditions, it exhibits reactivity and participates in various chemical reactions.

To prepare 1-bromo-4-methyl isobenzene, there are various synthetic methods.
First, it can be obtained from 4-methyl isobenzene through bromination reaction. In this reaction, 4-methyl isobenzene and bromine can replace hydrogen atoms at specific positions on the benzene ring under the action of appropriate catalysts such as iron filings or iron tribromide. Because methyl is an ortho-para-site group, under suitable conditions, bromine is more inclined to replace methyl para-sites to generate 1-bromo-4-methyl isobenzene. During the reaction, 4-methyl isobenzene is placed in a reaction vessel, an appropriate amount of bromine and a catalyst are added, and the reaction temperature and time are controlled. Usually under mild heating conditions, the reaction can proceed smoothly.
Second, it can be synthesized by constructing a benzene ring. First select a suitable starting material, such as an olefin or alkyne containing a specific substituent, and construct a benzene ring through a multi-step reaction. For example, starting with a chain compound containing methyl and a suitable functional group, the benzene ring skeleton is constructed through a Diels-Alder reaction, and then the benzene ring is modified to introduce bromine atoms. First, a series of reactions are carried out to form an intermediate with a 4-methyl isobenzene skeleton in the chain structure, and then the intermediate is brominated. Under suitable conditions, the bromine atom is positioned at the desired position to obtain 1-bromo-4-methyl isobenzene. Although this route has many steps, it can precisely control the position and structure of the substituent.
Third, it can also start from halogenated aromatics. If there is a suitable halogenated methyl benzene, such as a halogenated aromatic hydrocarbon with a halogen atom and a methyl group in a specific position, the position of the halogen atom can also be adjusted through an appropriate nucleophilic substitution reaction or other conversion reaction, and the synthesis purpose can also be achieved. The target product 1-bromo-4-methyl isobenzene was obtained by the migration or substitution of halogen atoms under appropriate nucleophilic reagents and reaction conditions. The reaction conditions needed to be precisely controlled to ensure that the reaction proceeded according to the expected path and high purity product was obtained.

If there is no storage of 4-methylpentenal, it is necessary to pay attention to it.
If it is not stored, it needs to be investigated.
It should be placed in the room of the building or pass, where there is no fire or source. This is to avoid the risk of high temperature. Because of its flammability, it is in danger of open fire, high temperature or explosion. The temperature should not exceed 30 ° C, and the phase temperature should also be controlled at the appropriate temperature to prevent its performance.
In addition, the storage container needs to be added. A sealed container must be used to prevent the escape of the container, and to avoid the biochemical reaction of the material in the air. And the container can withstand its corrosion, so as not to play a role in chemistry, so as to maintain the safety of storage.
It is also not to be ignored. The emergency management of fire equipment and leakage of the corresponding phase equipment should not be ignored. In summer, it is best to wait in the morning and evening, so as to reduce the high temperature and its impact. The tank (tank) used in the tank is not grounded, and the tank can be baffled with holes in order to generate less vibration, because it may cause danger.
The unloading process must be careful. The operator needs to be well-trained and abide by the operation process. The moving tank should be unloaded to prevent the package and container from being damaged. If the package is broken and causes its leakage, it will be as dangerous as life.
And on the way, it is necessary to oxidize, acid, and other substances, because of their activity. If they are not connected, they may cause violent reactions and form a large reaction.
Therefore, 4-methylpentenal is required to be stored in the environment, and all systems are followed. Pay attention to the general situation, so as to be safe.