1 4 Dihydroxyisoquinoline
quinoline thiophene imidazole thiazole

1,4-Dihydroxyisoquinoline

Taiy Chemical

    Specifications

    HS Code

    814509

    Chemical Formula C9H9NO2
    Molecular Weight 163.173 g/mol
    Appearance Solid
    Odor Odorless
    Melting Point 224 - 228 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol, DMSO
    Pka 8.5 (estimated)
    Logp 1.28 (estimated)
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading 1,4-Dihydroxyisoquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,4-dihydroxyisoquinoline?
    The main use of 1,4-difluorodistyrene is in many fields. In the field of materials science, it can be used as a key monomer in the synthesis of special polymer materials. Through delicate chemical reactions, 1,4-difluorodistyrene can be ingeniously integrated into the polymer skeleton, so that the synthesized material has unique physical and chemical properties. For example, it can improve the heat resistance of the material, so that the material can maintain good stability in high temperature environment, and it is not easy to deform and decompose. It can also enhance the mechanical properties of the material, such as improving the strength and toughness of the material, so that the material is more resistant to damage when subjected to external forces.
    In the field of medicinal chemistry, 1,4-difluorodistyrene is also an important synthetic intermediate. Due to its special molecular structure, it can participate in the construction process of various drug molecules. Medicinal chemists can modify and modify its structure to develop drugs with specific pharmacological activities. Some of the drugs synthesized on this basis may have unique therapeutic effects on certain diseases. For example, in the development of anti-tumor drugs, 1,4-difluorodistyrene-derived compounds may be able to inhibit the growth and spread of tumor cells through specific mechanisms of action, providing new possibilities for conquering tumor diseases.
    In organic synthesis chemistry, 1,4-difluorodistyrene, as a versatile synthetic block, can participate in the synthesis of many complex organic compounds. With the help of various organic reactions, such as coupling reactions, cyclization reactions, etc., chemists can use 1,4-difluorodistyrene as the starting material to construct organic molecules with diverse structures and special functions. These organic molecules also show potential application value in optoelectronic materials, catalysis, etc. For example, in optoelectronic materials, compounds based on 1,4-difluorodistyrene obtained through a specific synthesis path may have excellent photoelectric conversion properties, contributing to the development of new optoelectronic materials.
    What are the chemical properties of 1,4-dihydroxyisoquinoline
    1,4-Difluorodistyrene is an organic compound with the following chemical properties:
    First, it has the properties of an olefin. Its molecule contains carbon-carbon double bonds and can undergo an addition reaction. Just like an olefin encounters bromine water, the double bond of 1,4-difluorodistyrene can be added to the bromine elemental substance, causing the bromine water to fade. Taking bromine water as an example, during the reaction, the bromine-bromine bond in the bromine molecule breaks and is added to the carbon atoms at both ends of the carbon-carbon double bond to form a dibromine substitute. This reaction condition is usually mild and can be carried out at room temperature and pressure. At the same time, under suitable catalyst and temperature conditions, it can also be added to hydrogen, and the double bond becomes a single bond to form a saturated alkane derivative. This process can be used to prepare organic compounds with specific structures.
    Second, the properties of the benzene ring also exist. The benzene ring is a part of its structure, so it can undergo a typical substitution reaction of the benzene ring. For example, in the presence of Lewis acid catalysts, such as ferric chloride, halogenation reactions can occur with halogen elements. Take the chlorination reaction as an example, the chlorine atom will replace the hydrogen atom on the benzene ring to form a chlorinated 1,4-difluorodistyrene derivative. In this reaction, ferric chloride has a significant catalytic effect, which promotes the polarization of chlorine molecules, enhances its electrophilicity, and is more likely to attack the benzene ring. In addition, it can also undergo nitration reactions. In the mixed system of concentrated sulfuric acid and concentrated nitric acid, the nitro group replaces the hydrogen atom on the benzene ring to form nitro-substituted products.
    Third, because it contains fluorine atoms, the electronegativity of fluorine atoms is large, which will affect the distribution of molecular electron clouds and make the molecules exhibit unique properties. For example, fluorine-containing groups can enhance the lipid solubility of molecules and affect their solubility in different solvents. And due to the high carbon-fluorine bond energy, the chemical stability of 1,4-difluorodistyrene is improved, and it is more difficult to be destroyed in some chemical reactions. This property is quite valuable in the preparation of high-performance materials in the field of materials science.
    What are the synthesis methods of 1,4-dihydroxyisoquinoline?
    1% 2C4 -difluoroisobutyric acid light is an organic compound, and there are many synthesis methods. The following are described in detail by Jun.
    First, the corresponding halogenated hydrocarbon is used as the starting material. First, the halogenated hydrocarbon undergoes a nucleophilic substitution reaction with a fluorine-containing reagent to introduce a fluorine atom. For example, select a suitable chlorinated or brominated hydrocarbon, and react with a fluorine source such as potassium fluoride in a specific organic solvent, such as dimethyl sulfoxide (DMSO), and add a phase transfer catalyst, such as tetrabutylammonium bromide, at a suitable temperature, which can promote the replacement of halogen atoms by fluorine atoms. Subsequently, through a series of functional group conversion reactions, such as ester hydrolysis, acidification and other steps, the carboxyl group in the target molecule is constructed to obtain 1% 2C4-difluoroisobutyric acid.
    Second, the addition reaction of olefins is used. An olefin with a specific structure is used as a substrate to make it add to a fluorine-containing electrophilic reagent or a free radical. If electrophilic addition is used, a suitable fluorohalide can be selected. Under the action of catalysts such as Lewis acid, the double bond of the olefin is opened, and the fluorine atom and halogen atom are added to both ends of the double bond. Subsequent reaction steps such as hydrolysis and elimination are used to modify the addition product, and finally the molecular structure of 1% 2C4-difluoroisobutyric acid is formed. The addition reaction of free radicals requires the addition of fluorine-containing free radicals to olefins under the action of initiators, and then the synthesis of the target compound is completed.
    Third, through the conversion of carboxylic acid derivatives. Starting from relatively simple derivatives such as carboxylic acid esters or acyl chlorides, it is first fluorinated. Selective fluorinating reagents such as Selectfluor can be used to fluorinate specific positions in carboxylic acid derivatives under suitable reaction conditions. After that, through hydrolysis, rearrangement and other reactions, the molecular structure is adjusted to obtain 1% 2C4-difluoroisobutyric acid. This method requires precise control of reaction conditions to ensure the regioselectivity of fluorination and the smooth progress of subsequent reactions. < Br >
    When synthesizing 1% 2C4-difluoroisobutyric acid, a reasonable synthesis method should be selected according to the actual situation, such as the availability of raw materials, the controllability of reaction conditions, and the purity requirements of the target product, in order to achieve the purpose of efficient and high-quality synthesis.
    In which fields is 1,4-dihydroxyisoquinoline used?
    1% 2C4-difluorodistyrene is used in many fields. In the field of medicine, it can be used as a key intermediate. The structure of 1% 2C4-difluorodistyrene has unique chemical activity and can be converted into specific drug molecules by chemical synthesis to intervene in human physiological processes. For example, when developing drugs for the treatment of specific diseases, this is used as a starting material and a compound with specific pharmacological activity is constructed through a multi-step reaction.
    In the field of materials, it also plays an important role. Due to its special molecular structure, it can endow materials with excellent properties. For example, in the synthesis of polymer materials, introducing it into the main chain or side chain of the polymer can change the electrical, optical and thermal properties of the polymer. When preparing organic Light Emitting Diode (OLED) materials, 1% 2C4-difluorodistyrene can be used as a luminescent group or auxiliary structural unit to improve the luminous efficiency and stability of the material, and then improve the performance of OLED devices.
    In the agricultural field, 1% 2C4-difluorodistyrene can be used to synthesize pesticides. Its structural characteristics make the synthesized pesticides highly effective in inhibiting or killing specific pests or pathogens, and have relatively little impact on the environment, meeting the requirements of modern green agriculture for high efficiency and low toxicity of pesticides. For example, in the development of some new pesticides or fungicides, 1% 2C4-difluorodistyrene is used as an important part.
    In the field of fine chemicals, 1% 2C4-difluorodistyrene is an important raw material for the synthesis of a variety of fine chemicals. After a series of chemical reactions, fragrances, dyes, etc. can be prepared. For example, in dye synthesis, using its structural characteristics, new dyes with bright colors and good light resistance can be synthesized for textile, printing and dyeing industries.
    What is the market prospect of 1,4-dihydroxyisoquinoline?
    1,4-Difluorodistyrene, this is a special organic compound. In the current market structure, its prospects are unique.
    Looking at its uses, it has emerged in the field of materials science due to its unique optical and electronic properties. Among optoelectronic materials, it can be used as a key component to help improve the luminous efficiency and stability of materials, so it has potential application space in cutting-edge display technologies such as organic Light Emitting Diode (OLED), or it can promote display technology to a higher definition and energy saving.
    Furthermore, in the field of pharmaceutical chemistry, due to its unique chemical structure, it may become a key intermediate for the development of new drugs. With the continuous improvement of pharmaceutical technology, the demand for compounds with special active structures is increasing, and 1,4-difluorodistyrene may be able to take advantage of this trend to find a place in the process of innovative drug creation.
    However, its market also has challenges. The complexity and cost of the synthesis process are quite high, limiting its large-scale production and wide application. To expand the market, researchers need to fully study more efficient and economical synthesis methods to reduce production costs. And relevant regulations and policies are increasingly stringent on the environmental protection and safety requirements of chemical products. The production of 1,4-difluorodistyrene must also adhere to strict standards, which is also an important consideration for manufacturers.
    Overall, although 1,4-difluorodistyrene faces challenges, given its potential value in the fields of materials and medicine, if it can break through the difficulties of synthesis and regulations, the future market prospects are quite promising, and it is expected to occupy a place in the development wave of high-tech industries.