1 4 Dihydro 4 Oxo Quinoline 3 Carboxylic Acid
quinoline thiophene imidazole thiazole

1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

Taiy Chemical

    Specifications

    HS Code

    913773

    Name 1,4 - DIHYDRO - 4 - OX0 - QUINOLINE - 3 - CARBOXYLIC ACID
    Molecular Formula C10H7NO3
    Molecular Weight 189.17 g/mol
    Appearance Solid (usually light - colored)
    Melting Point Decomposes (approx. 280 - 290°C)
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Acidity Pka ~3.5 (carboxylic acid group)
    Uv Vis Absorption Absorbs in the UV region (around 250 - 350 nm)
    Ir Absorption Characteristic peaks for C=O (carbonyl of carboxylic acid around 1700 - 1720 cm⁻¹), C=O (quinolone carbonyl around 1650 - 1680 cm⁻¹), N - H stretch around 3300 - 3400 cm⁻¹)

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    What are the chemical properties of 1,4-dihydro-4-oxyquinoline-3-carboxylic acids
    The chemical properties of 1% 2C4-dialdehyde-4-oxyvaleric acid-3-butyric acid are also involved in the field of organic chemistry.
    This compound has functional groups such as aldehyde groups and carboxyl groups. The aldehyde group is active and can react with many reagents. First, it can carry out oxidation reaction. Under the action of appropriate oxidants, the aldehyde group can be converted into carboxyl groups. If a weak oxidant such as Toulon reagent (ammonia solution of silver nitrate) is used, the aldehyde group is oxidized to precipitate silver mirror, that is, silver element; if a strong oxidant such as potassium permanganate is used, other easily oxidized parts of the molecule may also be affected in addition to the oxidation of the aldehyde group. Second, the aldehyde group can undergo a reduction reaction. Under the action of reducing agents such as sodium borohydride and lithium aluminum hydride, the aldehyde group can be reduced to an alcohol hydroxyl group.
    Furthermore, its carboxyl group also has typical properties. The carboxylic group is acidic and can be neutralized with the base to generate the corresponding carboxylate and water. For example, it reacts with sodium hydroxide to form sodium carboxylate and water. At the same time, the carboxylic group can be esterified with the alcohol under the catalysis of the acid to form an ester compound. This reaction is a reversible reaction. It usually requires heating and concentrated sulfuric acid as a catalyst to promote the reaction in the direction of ester formation.
    In addition, the carbonyl group present in the molecule (in the oxovaleric acid site) also has unique reactivity. Carbonyl groups can undergo nucleophilic addition reactions, and many nucleophilic reagents such as alcohols and amines can be added to them to form new compounds. For example, under acid catalysis with alcohols, hemiacetal or acetal structures can be formed, which are important in organic synthesis and can be used to protect aldehyde groups or as intermediates for further reactions.
    The carbon chain structure of 4-oxyvaleric acid and 3-butyric acid parts makes this compound in organic reactions. Due to the activity of hydrogen atoms on the carbon chain, substitution reactions can occur. If under appropriate conditions, α-hydrogen on the carbon chain can be replaced by halogens, and this substitution reaction often needs to be carried out in the presence of light or catalysts.
    What are the synthesis methods of 1,4-dihydro-4-oxyquinoline-3-carboxylic acid?
    The synthesis method of 1% 2C4-carbon dioxide-4-photocatalysis-3-oxalic acid has the following methods:
    First, carbon monoxide and sodium hydroxide are used as the starting point, and the two are synthesized into sodium formate under high temperature and high pressure. After the dehydrogenation of sodium formate, oxalic acid is finally obtained. The raw materials in this way are easy to obtain, but the reaction conditions are harsh, and the requirements for equipment are quite strict. It must withstand high temperature and high pressure, and the cost remains high.
    Second, carbohydrates such as starch and glucose are used as the basis, and nitric acid is oxidized. Under the action of nitric acid, carbohydrates can be obtained through complex chemical changes. Oxalic acid. Although this raw material is ordinary, the corrosion of nitric acid is extremely strong, and many nitrogen oxides will be produced in production, which is harmful to the environment, and the subsequent treatment is also quite laborious.
    Third, ethylene glycol is used as a source and is catalyzed by air. Under the help of a catalyst and a suitable temperature and pressure, ethylene glycol reacts with oxygen in the air and gradually converts into oxalic acid. This path is relatively green, and the catalyst can be used repeatedly, which is slightly less harmful to the environment. However, the selection and preparation of the catalyst is extremely critical, which is related to the efficiency of the reaction and the quality of oxalic acid.
    Fourth, the method of photocatalytic synthesis. Under the light of the photocatalyst, simple substances such as carbon dioxide are driven by light energy to undergo a chemical reaction and eventually form oxalic acid. This is an emerging method that has the advantages of energy conservation and environmental protection. It can utilize solar energy and reduce dependence on traditional energy sources. However, it is still in the advanced stage of research. The activity and stability of photocatalysts need to be improved, and the reaction efficiency needs to be further improved before it can be practical.
    What are the applications of 1,4-dihydro-4-oxyquinoline-3-carboxylic acids in the field of medicine?
    1% 2C4 - carbon dioxide - 4 - photocatalysis - 3 - folic acid is used in the field of medicine and has multiple magical uses.
    Folic acid is used in the field of medicine and has a wide range of uses. First, it is related to the work of hematopoiesis. The hematopoietic process of the human body depends on the coordination of many factors, and folic acid is one of the keys. If folic acid is deficient, it can cause megaloblastic anemia. This is because folic acid is indispensable in DNA synthesis. If it is deficient, hematopoietic stem cells will divide and differentiate, and red blood cell development will be abnormal, eventually leading to anemia. Every time doctors encounter this disease, they often use folic acid as a medicine to make up for its deficiency and help hematopoiesis return to normal.
    Second, it is related to fetal development. During pregnancy Folic acid is essential for fetal neural tube development. In the early stages of pregnancy, if there is insufficient folic acid in the body of pregnant women, the risk of fetal neural tube defects increases sharply, such as spina bifida, anencephaly and other serious birth defects. Therefore, it is recommended that pregnant women take appropriate folic acid supplementation before and during pregnancy to ensure the normal development of fetal neural tubes and reduce the probability of such defects.
    Third, folic acid also plays a role in some anti-cancer therapies. Some cancer cells have a high demand for folic acid for growth and proliferation. Based on this, researchers have developed anti-cancer drugs targeting folic acid. Such drugs can block the access of cancer cells to folic acid, inhibit their growth, and provide new avenues for cancer treatment.
    There is also photocatalysis technology, which can drive reactions with light energy and has potential applications in carbon dioxide conversion. It may be possible to convert carbon dioxide into useful chemicals such as methanol by photocatalysis, which is of great significance for alleviating the greenhouse effect and energy regeneration. Although it seems to be separated from the field of medicine, it may provide new means and new ideas for drug synthesis, help develop novel drugs, and inject vitality into the development of medicine.
    What is the market price of 1,4-dihydro-4-oxyquinoline-3-carboxylic acid?
    What is the market price of 1% 2C4 - carbon dioxide - 4 - oxovaleric acid - 3 - citric acid? I should look into this matter carefully and describe it in ancient times.
    In today's world, the trade is complicated, and the prices of various things are volatile. The 1% 2C4, carbon dioxide, 4 - oxovaleric acid, 3 - citric acid have their own uses and different values in the market.
    1% 2C4 has a wide range of uses, or is involved in the general chemical industry, or is used for exquisite manufacturing. Its price often varies depending on the place of origin, season, supply and demand changes. If the place of origin is fertile and the output is quite abundant, but there are few people who want it, the price may decline; if the place of origin is not harvested, and there are many users, the supply is in short supply, the price will rise.
    Carbon dioxide, although common in the world, is also important in industry and people's livelihood. Or used for refrigeration, or to help make drinks. Its price also varies with the difficulty of production and the needs of the market. If the method of production is simple, the cost is low, and the market demand is not very urgent, the price is stable but not high; if it is difficult to produce, the cost increases greatly, and the number of people who use it, the price will also rise.
    4-Oxovaleric acid is useful in the fields of medicine and chemical industry. The market price of this substance often depends on the progress of research and development and the supply of raw materials. If there are new research and development, more methods can be made, and the raw materials are sufficient and easy to obtain, the price may be close to the people; if the research and development is slow and the raw materials are scarce and rare, the price will be high.
    3 -Citric acid is indispensable in the food, pharmaceutical and other industries. Its price is determined by factors such as climate, planting and processing. If the climate is suitable, the planting is extensive and the harvest is quite abundant, and the processing technology is mature, the supply in the market is sufficient, and the price may be stable; if the climate is abnormal, the planting is damaged, and the processing is difficult, the supply will be tight, and the price will rise automatically.
    All in all, the market price of these items is not static, but is actually affected by the interaction of many factors. If you want to know its exact value, you must carefully observe the market situation and pay attention to it from time to time.
    What are the storage conditions for 1,4-dihydro-4-oxyquinoline-3-carboxylic acid?
    The storage conditions of 1% 2C4-dioxy-4-oxyvaleric acid-3-succinic acid should be placed in a cool, dry and well-ventilated place. These compounds are highly reactive and vulnerable to external factors, so care should be taken when storing.
    In a cool place, the temperature should not be too high, and too high may cause the molecular structure of this compound to change, causing its properties to change. Generally speaking, the temperature should be maintained at 15 ° C to 25 ° C, so that its chemical properties can be relatively stable.
    Dry environment is crucial. The water vapor in the air may react with the compound or make it deliquescent, which will damage its quality. Therefore, in the storage place, there should be good moisture-proof measures, such as placing a desiccant around to absorb excess water vapor and keep it dry.
    Well-ventilated, can make the air smooth, avoid abnormal temperature and humidity due to local air circulation, and can disperse harmful gases that may be generated to prevent it from eroding the compound.
    Furthermore, keep away from fire, heat and strong oxidants. These compounds may be flammable and may be dangerous in case of fire or heat; strong oxidants are also easy to neutralize or cause other chemical reactions to deteriorate the compound. Storage places should also avoid light, especially direct light. Light can trigger photochemical reactions, causing compounds to decompose or undergo other adverse changes. It should be stored in an opaque container and hidden in a dark place, so that 1% 2C4-dioxy-4-oxyvaleric acid-3-succinic acid can be properly stored to stabilize its properties for later use.