1 2 3 4 Tetrahydro 1 Methylisoquinoline Hydrochloride
quinoline thiophene imidazole thiazole

1,2,3,4-Tetrahydro-1-methylisoquinoline hydrochloride

Taiy Chemical

    Specifications

    HS Code

    211292

    Chemical Name 1,2,3,4-Tetrahydro-1-methylisoquinoline hydrochloride
    Molecular Formula C10H14ClN
    Molecular Weight 183.68 g/mol
    Appearance Solid (usually white to off - white)
    Solubility Soluble in polar solvents like water and alcohols
    Melting Point Typically in a certain temperature range (data may vary, around 200 - 220°C approximately)
    Boiling Point Decomposes before boiling under normal pressure
    Pka A relevant pKa value depending on the environment (data may vary, around 8 - 9 for the basic nitrogen in some cases)
    Hazard Class May have irritant properties, check safety data sheet for details
    Storage Conditions Stored in a cool, dry place, protected from light

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    General Information
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    Frequently Asked Questions

    As a leading 1,2,3,4-Tetrahydro-1-methylisoquinoline hydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 1,2,3,4-tetrahydro-1-methylisoquinoline hydrochloride?
    1% 2C2% 2C3% 2C4-tetrahydro-1-methyl isobutyrate isoamyl ester. The physical properties of this substance are as follows:
    Its appearance is often colorless to light yellow transparent liquid. Looking at its color, the pure one is transparent and clear, almost colorless, but occasionally dyed slightly yellow due to some impurities or process differences. Smell it, it has a special and relatively soft fruity aroma, like a combination of various fruit aromas, like the freshness of apples and the elegance of pears, with subtle floral aromas, and the overall aroma is pleasant and not pungent.
    When it comes to boiling point, it boils at a specific temperature range under standard atmospheric pressure. This boiling point characteristic is determined by intermolecular forces. Its molecular structure imparts an attractive force to each other. To make the molecules break free from the liquid phase and turn into the gas phase, they need to reach a specific thermal energy, that is, the boiling point temperature.
    In terms of density, it is lighter than water. Measured by the mass per unit volume, the value is less than the density of water. This characteristic is due to the compactness and relative mass of the molecules, so that under the same volume, the mass is less than that of water.
    Solubility is also an important physical property. It exhibits good miscibility in organic solvents, such as ethanol, ether, etc., and can be mixed uniformly with it. However, in water, the solubility is quite limited, and it is mostly stratified. This is because the molecular polarity of the substance is significantly different from that of water molecules. According to the principle of similar miscibility, it is difficult to dissolve in water.
    Its refractive index also has a specific value. When light passes through, the internal structure of the substance affects the speed of light propagation, causing the direction of light to change. This property has important reference value in the identification and analysis of the substance.
    In summary, the physical properties of 1% 2C2% 2C3% 2C4-tetrahydro-1-methyl isobutyrate isoamyl ester are of critical significance in many aspects such as its separation, purification, identification and application.
    What are the chemical properties of 1,2,3,4-tetrahydro-1-methylisoquinoline hydrochloride?
    1% 2C2% 2C3% 2C4-tetrahydro-1-methylisoquinoline carboxylic acid amide, this physical property is special. It is an organic compound with certain chemical activity.
    Under normal temperature and pressure, it is mostly solid and stable. In case of hot topic, open flame or strong oxidizing agent, it is easy to cause chemical reaction, or cause combustion or even explosion risk, so storage and use need to be careful.
    Its solubility is characteristic. It has a certain solubility in organic solvents such as ethanol and acetone, but it is not good in water. This property is crucial in the selection of separation, purification and chemical reaction media.
    1% 2C2% 2C3% 2C4-tetrahydro-1-methyl isoquinoline carboxylic acid amide is weakly basic and can react with acids to form salts due to its nitrogen-containing molecular structure. This property is widely used in the field of drug synthesis. By reacting with different acidic substances, it may improve the solubility and stability of drugs and enhance their efficacy.
    It also has nucleophilic properties. Specific parts of the molecular structure can be used as nucleophiles to participate in nucleophilic substitution reactions. In organic synthesis, or as a key step in the construction of complex molecular structures, different functional groups can be introduced to expand the types and functions of compounds.
    In addition, it may have potential roles in biological activity. Some of them contain similar structural compounds, which have certain pharmacological activities after research, such as anti-tumor, antibacterial, etc. However, the specific biological activity of 1% 2C2% 2C3% 2C4-tetrahydro-1-methylisoquinoline formamide still needs more experimental investigation and verification.
    In what fields is 1,2,3,4-tetrahydro-1-methylisoquinoline hydrochloride used?
    1% 2C2% 2C3% 2C4-tetrahydro-1-methylisoquinoline formic anhydride is used in the fields of medicine and chemical industry.
    In the field of medicine, it is often the key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms. For example, when developing drugs for the treatment of nervous system diseases, its structural properties can be used to design compounds with high affinity and selectivity to precisely regulate neurotransmitter transmission or interfere with nerve cell signaling pathways, bringing hope for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
    In the chemical industry, it can be used as a raw material for the synthesis of special functional materials. Due to its active chemical properties, it can participate in a variety of chemical reactions to build polymer materials with unique properties. For example, synthesizing engineering plastics with excellent thermal stability and mechanical properties is used in aerospace, automobile manufacturing and other industries to improve the comprehensive properties of materials and meet the strict requirements of high-end fields. Or it is used to prepare special coating materials, giving the materials good corrosion resistance and wear resistance, and is widely used in metal protection, building decoration and other aspects.
    This compound has shown broad application prospects in the fields of medicine and chemical industry due to its unique chemical structure and properties, and has made great contributions to promoting technological innovation and development in related fields.
    What is the synthesis method of 1,2,3,4-tetrahydro-1-methylisoquinoline hydrochloride?
    The synthesis of 1% 2C2% 2C3% 2C4-tetrahydro-1-methylisoquinoline-5-carboxylic acid 5-methyl ester is an important topic in the field of organic synthetic chemistry. This compound has a specific chemical structure and potential application value, and the synthesis steps are complicated and need to be carefully controlled.
    The initial steps are often started with suitable starting materials. For example, benzene ring derivatives and nitrogen-containing heterocyclic compounds with corresponding substituents can be selected. Through a series of reactions, the benzene ring is connected to the nitrogen heterocyclic ring. This process may involve nucleophilic substitution reactions, and under suitable reaction conditions, the reactant molecules are precisely bound. For example, a moderately active halogenated benzene derivative and a nitrogen-containing nucleophilic reagent are selected. Under the catalysis of a base, nucleophilic substitution occurs to form a preliminary benzo-nitrogen heterocyclic structure.
    The subsequent steps require the conversion and modification of functional groups of the obtained intermediate products. To introduce tetrahydro structures, catalytic hydrogenation can be used. In the presence of appropriate catalysts, such as palladium-carbon catalysts, under certain temperature and pressure conditions, the unsaturated bonds are hydrogenated and reduced to form tetrahydroisoquinoline structures. This process requires strict reaction conditions, and temperature, pressure and catalyst dosage will all affect the selectivity and yield of the reaction.
    Furthermore, in order to introduce methyl and carboxyl methyl ester functional groups at specific positions, a specific organic reaction is required. When introducing methyl, methylation reagents, such as iodomethane, can be selected to react with intermediates under basic conditions to achieve methyl substitution. The introduction of carboxyl methyl ester functional groups may be achieved by esterification reaction. The corresponding carboxylic acid and methanol are used as raw materials and esterified under acid catalysis to form the target carboxyl methyl ester structure.
    During the synthesis process, each step of the reaction needs to be strictly monitored and purified. The reaction process is tracked by means such as thin-layer chromatography and column chromatography to ensure that the reaction achieves the desired effect. The resulting product is purified to obtain a high purity of 1% 2C2% 2C3% 2C4-tetrahydro-1-methylisoquinoline-5-formate 5-methyl ester. In this way, the target compound can be obtained through the reaction of multiple steps of delicate design and fine operation.
    How safe is 1,2,3,4-tetrahydro-1-methylisoquinoline hydrochloride?
    1% 2C2% 2C3% 2C4-tetrahydro-1-methylisonicotinamide This substance is life-threatening, and its safety must be explored in detail.
    To know its safety, first look at the chemical structure. This compound contains specific functional groups, or has specific chemical activities and reactivity. Some functional groups under specific conditions or chemically react with substances in the body of organisms, affecting the normal physiological function of cells. Like a sharp blade, if used improperly, it will hurt.
    Its toxicological properties are observed for the first time. Through animal experiments and in vitro cell experiments, its effects on organisms can be detected. Or observe its effects on the growth, development, and physiological indicators of experimental animals, or its cytotoxicity and genetic toxicity. If the animal shows growth retardation, organ damage, or cell mutation in the experiment, it indicates that its safety is questionable.
    Re-examine its behavior in the environment. If it enters the environment, its degradability and bioaccumulation need to be considered. If it is difficult to degrade and easy to bioaccumulate, it is afraid of enrichment in the environment, endangering the ecosystem, and then indirectly affecting human health.
    Consider its production and use process. During production, the safety of raw materials and intermediate products, operating conditions and protective measures are all important. When using, the route of exposure, dose and frequency are also critical. If there is no safety protection in production, workers are easily exposed to danger; during use, the exposure dose and frequency are large, and the user's health is threatened.
    In short, the safety of 1% 2C2% 2C3% 2C4-tetrahydro-1-methylisonicotinamide needs to be studied in detail in a comprehensive manner, and it must not be taken lightly. It must be like walking on thin ice in the abyss to ensure its safe application.