N-Methyl-1H-imidazole-4-carboxylic acid

N-methyl-1H-imidazole-4-carboxylic acid, this substance has a wide range of uses. In the field of medicinal chemistry, it is often a key raw material for the synthesis of delicate drug molecules. Geimidazole has a unique structure and can specifically bind to many targets in vivo. By introducing N-methyl and carboxyl groups, its physicochemical properties and biological activities can be fine-tuned. For example, when developing antibacterial drugs, compounds with strong effects on specific bacteria can be designed based on this. By interacting with key bacterial proteins or enzymes, the effect of inhibiting bacterial growth and reproduction can be achieved.
In the field of materials science, it also has functions that cannot be ignored. It can participate in the preparation of functional materials with excellent performance. For example, in the synthesis of some intelligent responsive polymer materials, N-methyl-1H-imidazole-4-carboxylic acids can be introduced as functional monomers, giving the material the ability to respond to specific environmental factors, such as pH value, temperature, etc. When environmental conditions change, the material structure and properties change accordingly, so as to achieve special functions such as substance separation and controlled release.
Furthermore, in the field of organic synthetic chemistry, it is an important building block for the construction of complex organic molecules. With the reactivity of the carboxyl group and the nitrogen atom on the imidazole ring, it can skillfully connect with other organic fragments through a variety of organic reactions, such as esterification, amidation, nucleophilic substitution, etc., to expand the diversity of molecular structures and help synthetic chemists create organic compounds with novel structures and unique functions, contributing to the development of chemical science.

N-methyl-1H-imidazole-4-carboxylic acid is also an organic compound. Its physical properties are quite worthy of investigation.
When it comes to appearance, this compound is often white to light yellow solid powder. This appearance feature is convenient for preliminary identification and distinction in actual operation.
Looking at its solubility, it has a certain solubility in common organic solvents, such as methanol, ethanol and other alcoholic solvents. This property makes it possible to select a suitable solvent system according to its solubility in related chemical experiments or industrial production for operations such as dissolution, reaction, and separation. In water, it also has a certain solubility, but compared with some compounds with stronger hydrophilicity, the solubility is slightly inferior.
As for the melting point, it has been experimentally determined to be within a specific temperature range. As an important physical constant of a substance, the melting point can be used to identify the purity of the compound. If the purity of the compound is quite high, the melting point is more acute and the melting range is narrower; conversely, if there are more impurities, the melting point will be shifted and the melting range will be wider.
Its density is also a key physical property. The density value reflects the mass of the substance per unit volume, and has important reference value in terms of measurement, mixing and related engineering design of the substance.
In addition, the stability of this compound also belongs to the category of physical properties. Under normal environmental conditions, it has certain chemical stability, but when exposed to extreme conditions such as high temperature, strong acid, and strong base, its structure may change. Understanding this stability characteristic is helpful to take appropriate measures during storage, transportation, and use of the compound to ensure that its quality and performance are not affected.
In summary, the physical properties of N-methyl-1H-imidazole-4-carboxylic acids are of indispensable significance in many fields such as chemical research and industrial applications.

To prepare N-methyl-1H-imidazole-4-carboxylic acid, you can follow the following methods.
First take 1H-imidazole-4-carboxylic acid as the starting material, which is the key raw material. Place it in an appropriate reaction vessel and add an appropriate amount of methylating reagents, common such as iodomethane or dimethyl sulfate. And add suitable bases, such as potassium carbonate, sodium carbonate, etc., whose function is to promote the reaction and make the reaction environment suitable for the occurrence of methylation reactions. This base can interact with methylating reagents to generate nucleophilic negative ions, which in turn can be substituted with 1H-imidazole-4-carboxylic acids. < Br >
When reacting, it is necessary to precisely control the temperature and time. Generally speaking, the temperature should be maintained within a certain range, such as using iodomethane as a methylating agent, and the temperature may be controlled between room temperature and 50 ° C, depending on the specific reaction process and effect. The time depends on the reaction monitoring results, or it may take several hours to ten hours. The progress of the reaction is often monitored by thin layer chromatography (TLC). The reaction can only be stopped when the raw material point disappears or the expected degree of reaction is reached.
After the reaction is completed, the reaction mixture is extracted with an appropriate solvent to separate the organic phase. If the product is impure, it can be purified by column chromatography or recrystallization. Take column chromatography as an example, select suitable stationary and mobile phases to separate the product from impurities. The recrystallization method requires selecting a suitable solvent, dissolving the product in the solvent, slowly cooling or evaporating the solvent to precipitate pure crystals.
In this way, through raw material selection, reaction operation, post-treatment and purification, N-methyl-1H-imidazole-4-carboxylic acid can be obtained.

I don't know what the price range of "N - Methyl - 1H - imidazole - 4 - carboxylic acid" is in the market. However, if you want to find out its price, you can find it from many places.
In the past, if you wanted to know the price of something, you could only know it by visiting the merchants in various cities and asking the price in person. In today's world, information is convenient and can be checked in detail on the websites of chemical trading platforms and chemical raw material suppliers. Or if the price is clearly listed, or you need to consult the customer service to know the price.
There are also those who take the exchange of industry as the key, in the forums and communities of the chemical industry, and talk with various industry players. They may tell the common price range based on experience.
However, the price of this chemical often changes due to the quality, quantity, supply and demand, and time. The superior price may be high, and the quantity may be discounted. If the supply exceeds the demand, the price may drop; if the supply exceeds the demand, the price may rise. Different seasons may also affect the price. Therefore, if you want to determine the price, you must comprehensively consider and check the information of multiple parties in detail before you can obtain a more accurate price range.

N - Methyl - 1H - imidazole - 4 - carboxylic acid (N - methyl - 1H - imidazole - 4 - carboxylic acid), also an organic compound. Its storage conditions are crucial, related to the stability and quality of the substance.
This compound should be stored in a cool, dry and well-ventilated place. In a cool environment, it can be protected from high temperature. Due to high temperature, the molecular activity of the compound is often enhanced, or it may cause decomposition and deterioration. The temperature should not exceed 25 ° C. If it is extremely hot in midsummer, it should be placed in an air-conditioned room or a temperature-controlled storage device.
Dry conditions are also indispensable. Water vapor in the air easily interacts with the compound, or causes adverse reactions such as hydrolysis. Therefore, it should be avoided in humid places. A desiccant, such as silica gel, can be placed in the storage area to absorb moisture in the air and maintain a dry environment.
Furthermore, good ventilation can disperse volatile gases that may accumulate and prevent local concentrations from causing safety hazards. If the compound is stored in a closed space and volatile, the gas will accumulate or cause pressure to rise, and even cause explosions and other hazards.
The choice of storage containers should not be underestimated. Corrosion-resistant materials such as glass or specific plastic containers should be used. The glass material is chemically stable and does not easily react with compounds; some special plastic containers also have good barrier properties and chemical corrosion resistance. The container must be tightly sealed to prevent the intrusion of air, water vapor, etc.
Immediately after use, the container should be sealed as before, and it must not be negligent, causing it to be exposed to the air for a long time. In this way, N-Methyl-1H-imidazole-4-carboxylic acid must be properly stored to maintain its inherent chemical properties and quality.