N-Heptafluorobutyrylimidazole

N-heptafluorobutyryl imidazole, this substance has a wide range of uses. In the field of organic synthesis, it is often used as an acylating agent. Due to the characteristics of heptafluorobutyryl in its structure, it has high activity and can smoothly acylate with many compounds containing active hydrogen, such as alcohols and amines. And because of its fluoride content, the introduction of fluorine-containing groups through its reaction can significantly change the physical and chemical properties of the product, which is of great significance in the fields of medicinal chemistry and materials science.
In the development of drugs, with the help of its acylation reaction, fluorine-containing drug molecules with unique physiological activities may be synthesized. Fluorinated drugs often have better fat solubility and metabolic stability, and are easier to penetrate biofilms, improving bioavailability and enhancing pharmacological activity.
In the field of materials science, the use of N-heptafluorobutyryl imidazole may be used to prepare fluoropolymer materials. Such materials may have excellent chemical resistance, low surface energy, and high temperature resistance, and have potential applications in coatings, plastics, fibers, and other fields.
In addition, in some analytical chemistry methods, it may also be used as a biochemical derivative reagent to improve the detection sensitivity and selectivity of analytes, and to facilitate more accurate component analysis and structural identification.

N-heptafluorobutyryl imidazole is also an organic compound. Its physical properties can be investigated. Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid, clear and with a specific odor.
When it comes to the boiling point, it is about 150-152 ° C. Under this temperature condition, the substance gradually transforms from liquid to gaseous state. This boiling point characteristic is very critical in the chemical process of separation and purification. Its melting point is also fixed, about -30 ° C. The melting point state and the transition of the substance from solid to liquid state are well-defined. The density of N-heptafluorobutyryl imidazole is about 1.62 g/cm ³, which is heavier than water. This density property is an important consideration in liquid-liquid separation, mixing and other operations. And because its molecular structure is rich in fluorine, its solubility is unique. It is soluble in many organic solvents, such as halogenated hydrocarbons such as dichloromethane and chloroform, and has a certain solubility in common alcohols and ether solvents. However, its solubility in water is poor. This difference in solubility has a significant impact on the selection of reaction media and product separation in chemical synthesis.
In addition, its vapor pressure characteristics cannot be ignored. In a certain temperature range, the vapor pressure is moderate, which affects the partial pressure of the substance in the gas phase, and then correlates with the volatilization rate. During storage and use, it is of great significance to control environmental conditions.

The chemical properties of N-heptafluorobutyryl imidazole are relatively unstable. It has active reaction characteristics due to the presence of heptafluorobutyryl and imidazole groups in its structure. There are many fluorine atoms in heptafluorobutyryl, which has strong electron-withdrawing properties and enhances the positive electricity of carbonyl carbons, making it vulnerable to attack by nucleophiles.
This substance is easy to hydrolyze in water. During hydrolysis, the hydroxyl groups in the water molecules attack the carbonyl carbons, causing the heptafluorobutyryl to detach and form heptafluorobutyric acid and imidazole-related products. In a humid environment, this hydrolysis reaction is spontaneous and fast, which
In organic synthesis reactions, although it can be used as an excellent acylation reagent, heptafluorobutyryl can be introduced. However, due to its activity, the reaction conditions need to be strictly controlled. If the reaction system has water vapor, or the temperature and pH are improper, it is easy to initiate side reactions, resulting in the yield and purity of the target product being affected.
In addition, its stability is also affected by the ambient temperature. At high temperatures, the reactivity is higher, or unnecessary decomposition or polymerization reactions are triggered. When storing, it needs to be sealed in a dry and cool place to prevent it from deteriorating due to the action of water and air, so as to maintain the relative stability of chemical properties and achieve the expected reaction effect when used.

For N-heptafluorobutyryl imidazole, many things should be paid attention to when using it. This substance is highly active and easily reacts with compounds rich in active hydrogen such as water and alcohols. Therefore, when storing, make sure that it is in a dry and sealed environment, and be careful to prevent moisture from invading, so as not to lose its due activity.
Furthermore, because of its certain toxicity and irritation, it is necessary to strictly observe safety procedures when operating. Operate in a well-ventilated environment, and it is best to operate in a fume hood to prevent inhalation of the volatile gases of the substance and harm to the respiratory tract. If it accidentally touches the skin or eyes, rinse with plenty of water immediately and seek medical treatment in time.
During use, it is also crucial to precisely control the dosage. Because of its high reactivity, the dosage is slightly poor, which may cause the reaction results to be very different. And the equipment used should also be clean and dry to prevent impurities from interfering with the reaction process. At the same time, the reaction conditions such as temperature and time also need to be precisely controlled. Under different reaction conditions, the rate and product of the substance participating in the reaction may vary greatly.
Furthermore, after use, proper disposal of the remaining N-heptafluorobutyryl imidazole and related waste cannot be ignored. It needs to be treated harmlessly in accordance with relevant regulations, and must not be discarded at will to avoid pollution to the environment. In short, when using this substance, be careful and pay attention everywhere to ensure safe operation and smooth reaction.

N-heptafluorobutyryl imidazole, the price of this product in the market is difficult to be fixed. Its price often changes due to many reasons, such as the coarseness of the manufacturing process, the situation of demand, the quality of the product, and even the region and season of trade relocation.
In the past, if it was well-made and supplied in major commercial ports, its price would be high. Because of the refining method, it requires a lot of effort, and in prosperous commercial ports, its demand is also prosperous, and the price will rise. If it is a high-quality material, it is suitable for exquisite industries, such as pharmaceutical research, high-tech material manufacturing, etc., the price will be very high.
However, if the manufacturing process is simple, and the supply and demand are slow, the price should be leveled. Or its products are only suitable for ordinary industries, and the price is difficult to be high.
To know its exact price at this time, it is advisable to consult the people of chemical materials, or explore the e-commerce platforms of various chemical products, in order to know its current approximate value in the market.