Chemical Formula | C5H8N2 |
Molecular Weight | 84.13 g/mol |
Appearance | Colorless to pale yellow liquid |
Odor | Characteristic amine - like odor |
Melting Point | -10 °C |
Boiling Point | 199 - 201 °C |
Density | 0.978 g/cm³ at 20 °C |
Solubility In Water | Miscible |
Flash Point | 84 °C |
Pka | 7.3 (in water at 25 °C) |
Vapor Pressure | 0.133 kPa at 48.8 °C |
Refractive Index | 1.517 - 1.519 (20 °C) |
What are the main uses of N-Ethylimidazole?
N-ethyl imidazole is also an important substance for chemical processing. It is widely used in the chemical industry and is often a catalytic agent. It has a special structure and can be used in various chemical reactions to promote the reaction rate, increase production, reduce stress time, and save energy. Therefore, it is very important.
In the polymerization process, it can be used as a catalytic medium to make alkenyl monomers polymerize into high polymers, such as alkenyl polymerization to make plastics. The addition of this agent makes it easy to control and obtain high-quality plastics. And in the production of ionic liquids, N-ethyl imidazole is also a key substance. Ionic liquids have the advantages of low autoclave pressure, stable hot topic, and wide liquid path. When prepared, N-ethyl imidazole and haloalkanes should be combined to obtain imidazole ionic liquids, which are useful in the fields of solvent, catalysis, and electrochemistry.
In the field of medical chemistry, N-ethyl imidazole also exhibits its functions. or as an intermediate for drug synthesis, a combination of auxiliary drugs, to form a specific drug. And it is also involved in the production of biomedical materials, such as the preparation of special film materials, drug-loaded bodies, etc., or rely on its participation in the chemical reaction, and externalize the material with good performance.
In the dyeing and weaving industry, or as a dyeing aid agent. It can change the surface of the fabric, promote the dyeing of the dye, increase the uniformity and fastness of the dye, and make the dye good and durable.
In short, N-ethyl imidazole has its functions that cannot be ignored in the chemical, medical, dyeing and weaving industries, and contributes a lot to the industry.
What are the physical properties of N-Ethylimidazole?
N-ethylimidazole is one of the organic compounds. Its physical properties are quite unique. Looking at its appearance, at room temperature, it is a colorless to light yellow transparent liquid, clear and clear, like morning dew.
When it comes to the melting point, it is about -30 ° C. This property allows it to maintain a liquid state in a lower temperature environment, just like smart water, not bound by a little cold. The boiling point is between 217-218 ° C. When the temperature rises to this point, it is like a butterfly that has emerged, sublimated from liquid to gaseous.
Its density is about 1.02 g/cm ³, which is slightly heavier than water. If it is placed in one place with water, it can be seen that it settles steadily at the bottom of the water, like a treasure hidden in the bottom of the water. In terms of solubility, N-ethyl imidazole exhibits extraordinary ability and is very soluble in water. The two touch and blend instantly, just like old friends reunite, intimate; it can also be miscible with many organic solvents, such as ethanol, acetone, etc., which can coexist harmoniously with it to form a uniform mixed system.
In addition, N-ethylimidazole also has a certain degree of hygroscopicity, just like a dry sponge, which quietly absorbs water vapor in the air and maintains its own moisture. These many physical properties make it widely used in chemical, materials and many other fields, and it is a rare and important chemical substance.
What are the chemical properties of N-Ethylimidazole?
N-ethyl imidazole is an organic compound. It is active and has many specific chemical properties.
This substance contains an imidazole ring, and the nitrogen atom in the ring has a lone pair of electrons, making it alkaline to a certain extent. It can form salts with acids, just like ancient bases and acids and generate new compounds. In the stage of chemical reactions, it often acts as a ligand and complexes with metal ions, just like a wise man assisting a monarch to form a stable complex. This property is widely used in the field of catalysis.
The nucleophilicity of N-ethyl imidazole should not be underestimated. Its nitrogen atom can attack electrophilic reagents and participate in many nucleophilic substitution reactions. If it encounters halogenated hydrocarbons, it will be like a warrior encountering an enemy and react to form corresponding substitution products.
Furthermore, its solubility also has characteristics, and it can be soluble in common organic solvents, such as ethanol and acetone, just like fish get water. This solubility brings convenience to its organic synthesis operation. Because its structure has both long chains of alkyl groups and imidazole rings, it has also been involved in surfactants and other fields, which can change the surface properties of the system, just like a skilled craftsman carefully adjusting the appearance of utensils. Its stability is acceptable under normal conditions. However, in extreme situations such as high temperature and strong oxidizing agent, the structure will also be broken, and the reaction will change, just like a strong castle will collapse under the attack of a strong enemy. In short, N-ethyl imidazole plays an important role in many fields such as chemical industry and materials due to its unique chemical properties.
What are the synthesis methods of N-Ethylimidazole?
N-ethyl imidazole is also an organic compound. Its synthesis method used to follow the classic path. One method is to use imidazole and halide as raw materials, in an appropriate solvent, with a base as a catalyst, and the two perform nucleophilic substitution. Among them, the solvent or choose ethanol and acetone, and the base can be potassium carbonate, sodium hydroxide and the like. During the reaction, the temperature needs to be controlled in a suitable environment, usually near the reflux temperature, so that the reaction can proceed smoothly. After several hours or even tens of hours of reaction, the product is obtained, and then purified by distillation and recrystallization to obtain pure N-ethyl imidazole. < Br >
There are also those who use imidazole and diethyl sulfate as raw materials. This is also a nucleophilic substitution reaction, in which the ethoxy group of diethyl sulfate is combined with the nitrogen atom of imidazole to form N-ethyl imidazole. The reaction is usually carried out in organic solvents, such as acetonitrile, at room temperature or slightly higher. In this process, the proportion of reactants, reaction time, temperature and other factors are all related to the yield and purity of the product.
In addition, imidazole and ethylene are used as raw materials, and N-ethyl imidazole is synthesized through an addition reaction with the help of a catalyst. This catalyst or transition metal complex, the reaction conditions are relatively mild, but the activity and selectivity of the catalyst requirements are quite high. Synthesis method, each has its advantages and disadvantages, according to the actual needs, choose the appropriate method.
What are the precautions for N-Ethylimidazole during use?
N-Ethylimidazole is an organic compound. There are many things to be paid attention to during use.
Bear the brunt, and safety is of paramount importance. This compound is toxic and irritating to a certain extent, and may cause damage to the skin, eyes and respiratory tract. Therefore, when using, protective measures must be taken, such as wearing suitable protective gloves, protective glasses and gas masks, to avoid direct contact and inhalation. In case of inadvertent contact, rinse with plenty of water immediately and seek medical assistance according to the specific situation.
Furthermore, its chemical properties cannot be ignored. N-ethylimidazole is alkaline and can react with acids, so it should be avoided to store or mix with strong acidic substances to prevent danger caused by violent reactions. At the same time, it may participate in chemical reactions under certain conditions. When using it, it is necessary to strictly follow the operating procedures and control the reaction conditions, such as temperature, concentration, reaction time, etc., to ensure that the reaction proceeds as expected and avoid unexpected conditions.
Storage is also exquisite. Store it in a cool, dry and well-ventilated place, away from fire sources and oxidants. Because of its flammability, it will burn in case of open flames, hot topics or burn, proper storage can reduce the risk of fire.
In addition, the place of use should be well ventilated to reduce its concentration in the air and reduce the potential threat to human health. At the same time, the waste generated during use must be properly disposed of in accordance with relevant regulations and cannot be discarded at will to prevent pollution to the environment. In short, when using N-ethylimidazole, it is necessary to be rigorous and careful to fully ensure the safety of personnel and the environment.