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What is the chemical structure of Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate?
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"Methyl (S) 2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole -6 - carboxylate", according to its name, "Methyl", methyl is also a genus of hydrocarbons, often referred to as "-CH". " (S) " indicates that its configuration is S-type, which is related to the three-dimensional structure of the molecule.
"2- (Chloromethyl) ", which is said to be connected to the second position of the main structure, with chloromethyl and chloromethyl, that is, "-CH ³ Cl", and the chlorine atom is connected to methylene.
"1- (2 - oxetanylmethyl) ", which is known to be connected to 2-oxetanylmethyl and 2-oxetanylmethyl at the first position, is an oxygen-containing quaternary heterocyclic ring. The second position of this ring is connected to methylene, and the methylene is reconnected to the main structure.
"1H-benzo [d] imidazole", which is the parent nucleus of benzimidazole, is formed by fusing a benzene ring with an imidazole ring. The benzene ring is a six-membered carbon ring with a conjugated large π bond; the imidazole ring is a five-membered nitrogen-containing heterocycle with two nitrogen atoms.
"6-carboxylate" indicates that there is a carboxylate group attached to the 6-position of the benzimidazole parent nucleus. The general formula of the carboxylate group is "-COOR", where "R" is methyl, that is, "-COOCH".
In summary, the structure of this compound, with benzimidazole as the parent nucleus, is connected to 2-oxacyclobutyl methyl at 1 position, chloromethyl at 2 position, and carboxylic acid methyl at 6 position, and the whole is S configuration. Although the text description is a bit complicated, the wonders of the chemical structure lie in the delicate structure.
What are the main uses of Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate?
Methyl (S) - 2 - (chloromethyl) - 1 - (2 - oxy cyclobutanyl methyl) - 1H - benzo [d] imidazole - 6 - carboxylic acid ester, this substance has a wide range of uses. In the field of pharmaceutical research and development, it seems to be a key cornerstone for the creation of new drugs, which can precisely act on biological targets related to specific diseases. It is like a carefully crafted key to open the door to the treatment of diseases, and may play an indispensable role in the development of anti-tumor and antiviral drugs.
On the stage of organic synthesis, it is like an active participant, and with its own unique structural characteristics, it can act as a key intermediate. Just like an indispensable and important component when building a magnificent building, it helps to synthesize many organic compounds with complex structures and special effects, and contributes to the development of organic synthetic chemistry.
In the world of materials science, it may also make a name for itself. Maybe it can give materials some novel properties by virtue of its own structure, such as improving the stability of materials, enhancing the interaction between materials and other substances, etc., like injecting magical power into materials, so that they can show excellent performance in specific application scenarios.
What are the synthesis methods of Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate?
The synthesis of methyl (S) -2- (chloromethyl) -1- (2-oxy-butylmethyl) -1H-benzo [d] imidazole-6-carboxylic acid esters is an important topic in the field of chemistry. In the past, the synthesis method was reported, or it was obtained by a multi-step reaction with a specific starting material.
The first step is to take a benzimidazole derivative with a specific structure. This derivative is halogenated and a halogen atom is introduced at a suitable position to facilitate the subsequent reaction. The halogenating agent used, or a specific compound containing chlorine, requires precise regulation of the reaction conditions, such as temperature, reaction time and solvent selection, all of which are related to the reaction effect. < Br >
In the second step, the halogen-containing intermediate and the reagent containing 2-oxy heterocyclic butyl methyl structure are carried out under the catalysis of alkali for nucleophilic substitution. The type and amount of base have a great influence on the reaction process, aiming to promote the smooth combination of the two to form key carbon-carbon or carbon-heteroatom bonds.
Furthermore, the obtained intermediate is further modified to introduce chloromethyl. This step may require a specific protective group strategy to avoid affecting other active checking points. The selection and removal conditions of protective groups are both key considerations in the synthesis.
Then, through a series of reactions, such as esterification, the methyl carboxylate ester group is introduced at a suitable position. This process requires the selection of suitable esterification reagents and reaction conditions to ensure that the reaction is efficient and selective.
During each step of the reaction, the separation and purification of the product is also crucial. Chromatography, recrystallization and other means are often used to obtain high-purity products to ensure the smooth follow-up reaction and the quality of the final target product. The synthesis path needs to comprehensively consider many factors such as reaction feasibility, cost, yield and environmental protection. After repeated optimization, a satisfactory synthesis effect can be achieved.
What are the physicochemical properties of Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate?
"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty, but it does not involve the physical and chemical properties of "Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate". Therefore, the following is based on common chemical knowledge and is described in the style of ancient Chinese.
This compound is called methyl (S) -2- (chloromethyl) -1- (2-oxy heterocyclobutylmethyl) -1H-benzo [d] imidazole-6-carboxylate. Its physical properties, under normal conditions, or as a solid, due to the presence of benzimidazole and other structures, the intermolecular force is strong, causing its melting point or higher. Looking at its structure, it contains chloromethyl, and the chlorine atom has a certain electronegativity, or affects its solubility. In organic solvents, such as dichloromethane, chloroform and other halogenated hydrocarbon solvents, due to their structural similarity, or have a certain solubility. In water, due to its strong overall organicity, the solubility may be limited.
In terms of its chemical properties, the chlorine atom of chloromethyl has high activity and is prone to nucleophilic substitution reactions. Nucleophilic reagents such as alcohols and amines can attack chlorine atoms and cause chlorine atoms to leave to form new compounds. Furthermore, benzimidazole rings have certain aromatic properties and can undergo electrophilic substitution reactions. When encountering suitable electrophilic reagents, such as bromine and nitric acid, corresponding substituents can be introduced into benzimidazole rings. However, 2-oxy-butyl-methyl, oxy-butane structure is relatively active, under acidic or basic conditions, or ring-opening reaction occurs, resulting in the corresponding ring-opening product. Its carboxylate part, under acidic conditions, can be converted into the corresponding carboxylic acid, and the carboxylic acid has a certain acidity and can be neutralized with bases.
What is the price range of Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole-6-carboxylate in the market?
I don't know what you mean by "Methyl (S) -2- (Chloromethyl) -1- (2-oxetanylmethyl) -1H-benzo [d] imidazole -6 - carboxylate" in the market price range. This may be a rare chemical, and its price is determined by many factors, such as purity, yield, and market supply and demand.
If it is a commonly available chemical with wide demand and abundant output, the price may be relatively easy; however, if it is difficult to prepare, requires complicated processes, and the output is scarce, and only needs in specific fields, its price will be high.
Furthermore, different suppliers and purchase quantities can also cause significant price differences. To know the exact price range, you need to consult chemical raw material suppliers, chemical reagent sellers, or check the relevant information on the chemical product trading platform to obtain a more accurate price range. It is a pity that I cannot directly give you the price range of this chemical.