methyl 1H-benzimidazole-5-carboxylate

"Methyl 1H - benzimidazole - 5 - carboxylate", its chemical structure is formed by connecting a benzimidazole ring with a methyl ester group. The benzimidazole ring is a nitrogen-containing heterocyclic structure, which is formed by fusing a benzene ring with an imidazole ring. Here, 1H means that the hydrogen atom is attached to the nitrogen atom at the 1st position of the imidazole ring. And 5 - carboxylate refers to the structural fragment of methyl carboxylate connected to the 5th position of the benzimidazole ring, that is, the - COOCH 🥰 group. The chemical structure combines the special electronic effect of the benzimidazole ring and the chemical activity of the methyl ester group, which is of great significance in the fields of organic synthesis and medicinal chemistry. Due to its unique structure, it can participate in many chemical reactions, such as nucleophilic substitution, cyclization, etc., and has potential application value in the creation of new drugs and materials.

Methyl-1H-benzimidazole-5-carboxylic acid ester, this substance is an organic compound with unique physical properties. It is often in a solid state at room temperature, with a specific melting point and boiling point. The melting point is the temperature at which the substance changes from solid to liquid. After experimental testing, the melting point of methyl-1H-benzimidazole-5-carboxylic acid ester is in a specific range, which can help identify and purify the substance.
In addition, its solubility is also an important physical property. In common organic solvents, such as ethanol, acetone, etc., it has a certain solubility. However, in water, the degree of solubility is limited. This difference in solubility is due to the difference in the interaction between the molecular structure of the compound and the solvent molecules.
Its appearance is mostly white or off-white crystalline powder, and this color and morphology are convenient for preliminary identification. And the density of the substance is also a specific value. Although it does not resemble the melting point and solubility is often concerned, the density data is also crucial in some fine chemical or research scenarios.
In addition, the stability of methyl-1H-benzimidazole-5-carboxylate is quite good, and it can maintain its own structure and properties under conventional environmental conditions. However, under special conditions, such as high temperature, strong acid and alkali, etc., or chemical reactions occur, causing its structure and properties to change. This stability provides convenience for its storage and use, and it also needs to be properly preserved and applied according to its characteristics.

Methyl-1H-benzimidazole-5-carboxylic acid esters are a class of organic compounds. They have a wide range of uses and can demonstrate their important value in many fields.
In the field of pharmaceutical chemistry, this compound is often used as a key intermediate in drug synthesis. Geinbenzimidazole has a unique biological activity and can interact with specific targets in organisms. Using methyl-1H-benzimidazole-5-carboxylic acid esters as starting materials, chemically modified and derived, a variety of drugs with therapeutic effects, such as antibacterial, antiviral, and anti-tumor drugs, can be created. < Br >
In the field of materials science, it also has considerable uses. It can participate in the preparation of special functional materials, such as some materials with fluorescent properties. Because its molecular structure can emit fluorescence under specific conditions, it can be used in optical sensors, biological imaging, etc., to help researchers observe and study the properties of substances and physiological processes in organisms at the microscopic level.
In addition, it also has its uses in the field of agricultural chemistry. Or it can be used as a raw material for pesticide synthesis. After rational design and transformation, pesticide products with control effects on crop diseases and pests can be prepared, which can help agricultural production, ensure the healthy growth of crops, and improve yield and quality.
In summary, methyl-1H-benzimidazole-5-carboxylic acid esters play an important role in many fields such as drugs, materials, and agriculture due to their unique chemical structure, providing assistance for the development of various fields.

The synthesis methods of methyl-1H-benzimidazole-5-carboxylic acid esters have different paths. The following are common methods:
First, the starting materials are phthaleamine and dimethyl oxalate. In a suitable reaction vessel, mix phthaleamine and dimethyl oxalate in a certain proportion, and add an appropriate amount of catalyst, such as some metal salts. When heated to a certain temperature, in this process, the phthaleamine and dimethyl oxalate undergo a condensation reaction to form an intermediate product first. After cyclization, the final methyl-1H-benzimidazole-5-carboxylic acid ester is obtained. This reaction condition needs to be strictly controlled, and both temperature and reaction time have a great influence on the yield of the product. If the temperature is too high, or the side reactions increase, the purity of the product will decrease; if the temperature is too low, the reaction rate will be slow and take a long time.
Second, 5-nitro-phthaleamine and methyl formate are used as raw materials. First, 5-nitro-phthaleamine is dissolved in a suitable solvent, and then methyl formate is added. Under specific conditions, the nitro group of 5-nitro-phthaleamine is reduced and converted into an amino group. At the same time, a series of reactions such as condensation and cyclization occur with methyl formate to gradually form the target product. In this process, the conditions of the reduction reaction are particularly critical, and the selected reducing agent and the pH of the reaction system are all related to the formation and quality of the product.
Third, it can also be achieved through other raw material combinations and reaction paths. However, no matter what method, it is necessary to carefully consider the reaction conditions and strive to improve the yield and purity of the product to meet the needs of practical applications.

In the Wuguan market, the price of methyl-1H-benzimidazole-5-carboxylic acid ester often varies depending on the purity of the product and the supply and demand situation. This product is widely used in various fields of chemical industry, such as pharmaceuticals, organic synthesis, etc.
If it is pure and high quality, the price will be high; if it is pure and low, and there are many impurities, the price will be low. Furthermore, the supply and demand of the market are also the main reasons. If there are many applicants, but the supply is limited, the price will rise; if the supply exceeds the demand, the price may drop.
In the past, at a certain time, the price of this product with pure quality can reach tens of gold per gram; and if it is pure and poor, the price may only be a few gold per gram. However, the market conditions change rapidly, and the price fluctuates accordingly.
In addition, the buyer's region and purchase volume are also related to the price. If you buy in bulk, you may be given a discount, and the price is low; if you buy sporadically, the price may be high. And in different places, due to differences in logistics, taxes, etc., the price is also different.
Therefore, in order to know the exact price of methyl-1H-benzimidazole-5-carboxylate, you need to check the market conditions carefully, consult the merchants, and compare the price to obtain a more accurate number.