Imidazole,2-methyl-1-(p-nitrophenyl)- (7CI)

This is about the chemical structure of "2-methyl-1- (p-nitrophenyl) imidazole (7CI) ". This compound is based on the imidazole ring, with a methyl group at two sites on the ring, and a p-nitrophenyl group at one site.
The imidazole ring has a five-membered heterocycle of a dinitrogen atom. Its structure is stable, its properties are unique, and it is very important in many organic reactions and biological processes. The methyl group is a simple alkyl group. Addition to the imidazole ring at two sites can change its electron cloud distribution and steric resistance, which in turn affects the physical and chemical properties of the compound.
The p-nitrophenyl group has a nitro group attached to the para-site of the phenyl group. The nitro group is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, causing the compound to have specific electronic properties and reactivity. This structure, due to the interaction of imidazole ring, methyl group and p-nitrophenyl group, makes the compound exhibit unique chemical behavior, which may be potentially used in the fields of medicine, materials and so on.

"The physical properties of this' 2-methyl-1- (p-nitrophenyl) imidazole (7CI) 'have the following characteristics. It is an organic compound, with a crystalline appearance and a light yellow to light brown color. The melting point is quite critical, about 180-185 ° C. At this temperature, the substance gradually melts from solid to liquid, and this melting point characteristic can help to distinguish and purify.
In terms of solubility, it has a certain solubility in common organic solvents, such as ethanol and acetone, but its solubility in water is relatively low. This characteristic allows separation and extraction according to the difference in solubility in related chemical operations.
Stability cannot be ignored either. It is relatively stable in a dry environment at room temperature and pressure. However, when exposed to strong oxidizing agents, strong acids or strong bases, it is prone to chemical reactions and the structure is damaged.
Its density is about 1.3-1.4 g/cm ³. This physical quantity reflects the mass of the substance per unit volume, which is of great significance in material calculation and related process design.
In addition, the substance contains specific functional groups, such as imidazole ring and nitrophenyl group, which cause it to have absorption properties at specific wavelengths of light. It can be used as a basis for qualitative and quantitative research in the field of spectral analysis. All kinds of physical properties are of great value in chemical synthesis, drug research and development, and researchers can design experiments and develop applications according to their characteristics.

"This product'Imidazole, 2-methyl-1- (p-nitrophenyl) - (7CI) ', the Chinese name or 2-methyl-1- (p-nitrophenyl) imidazole, has a wide range of main uses. In the field of medical chemistry, it is often used as a key intermediate and participates in the synthesis process of many drugs. Due to its unique chemical structure, it can react with many bioactive molecules to help build compounds with specific pharmacological activities, providing an important cornerstone for the development of new drugs.
In the field of materials science, this substance can be used to prepare functional materials. For example, introducing it into a polymer material system through a specific process can endow the material with unique optical and electrical properties, or enhance the stability and durability of the material, thereby meeting the needs of different fields for special material properties.
In organic synthetic chemistry, as an efficient organic reagent, it can promote the smooth progress of many organic reactions. With its activity check point in its structure, it can participate in nucleophilic substitution, cyclization and other reactions, providing an effective path for the synthesis of complex organic compounds, helping chemists to create more novel and potentially valuable organic molecular structures. "

To prepare "Imidazole, 2 - methyl - 1 - (p - nitrophenyl) - (7CI) ", the method is as follows:
Common method, or from a suitable nitrophenyl-containing halogen, react with 2 - methylimidazole in a suitable solvent under the catalysis of a base. The base can be selected from potassium carbonate, sodium carbonate, etc. Solvents such as N, N - dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc., can help the reactants to dissolve and facilitate the reaction. When reacting, it is necessary to control the temperature moderately. Generally, under the condition of heating and reflux, the two can fully react, and undergo the process of nucleophilic substitution. The halogen atom is replaced by the nitrogen atom of 2-methylimidazole, so as to obtain the target product.
Or find another way, use 2-methylimidazole as the starting material, and first activate it appropriately, such as by reacting with some activating reagents to enhance the activity of the nitrogen atom on the imidazole ring. Then, react with a nitrophenyl-containing electrophilic reagent, which can be an active ester, an acyl halogen, etc. prepared by a special method. In a suitable reaction system, the electrophilic reagent undergoes an electrophilic substitution reaction with the activated 2-methylimidazole to construct the structure of the target product.
Furthermore, the strategy of constructing an imidazole ring can be considered to prepare it. Select suitable raw materials containing methyl and nitrophenyl groups, and gradually build an imidazole ring structure through multi-step reactions. For example, using the corresponding aldodes, amines, ketones, etc. as starting materials, through a series of reactions such as condensation and cyclization, methyl and p-nitrophenyl groups are ingeniously introduced, and finally the preparation of "Imidazole, 2-methyl-1- (p-nitrophenyl) - (7CI) " is completed. However, this approach is often complicated, and it is necessary to carefully control the conditions of each step of the reaction and the purification of the intermediate in order to obtain a pure product.

"Imidazole, 2 - methyl - 1 - (p - nitrophenyl) - (7CI) ", that is, 2 - methyl - 1 - (p - nitrophenyl) imidazole, the market prospect of this product is related to many parties.
Looking at its properties, this compound has a specific chemical structure and activity, and has potential uses in the field of chemical and pharmaceutical research and development. In the chemical industry, it may be a key intermediate in organic synthesis. With its unique structure, it can derive many high value-added products. However, the complexity and cost of the synthesis process affect its prospects for large-scale application in the chemical industry. If the process is optimized and the cost is controlled, it may be widely used in the chemical market.
At the pharmaceutical research and development level, due to the imidazole ring and nitrophenyl group, or biological activity, it can be targeted at specific disease targets. However, the road to new drug development is long, and each step requires a lot of manpower, material resources and time, from initial screening of activity, efficacy verification, to safety evaluation. If preclinical research shows good activity and safety, and is recognized by regulatory authorities, it is expected to become a new type of drug, with broad prospects; conversely, if the research encounters problems, such as high toxic and side effects or poor efficacy, its market application may be limited.
In summary, although 2-methyl-1- (p-nitrophenyl) imidazole has potential, the market prospect depends on factors such as synthesis process optimization, pharmaceutical R & D achievements and market competition. Only by overcoming many challenges can we achieve a broad market.