Imidazole 2 Carbaldehyde
quinoline thiophene imidazole thiazole

imidazole-2-carbaldehyde

    Specifications

    HS Code

    678478

    Chemical Formula C4H4N2O
    Molar Mass 96.09 g/mol
    Appearance Solid
    Color White to off - white
    Odor Characteristic
    Melting Point 145 - 147 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading imidazole-2-carbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of imidazole-2-carbaldehyde?
    Imidazole-2-formaldehyde, an organic chemical, has a wide range of uses.
    First, it plays a significant role in the field of drug synthesis. Due to its unique chemical structure, it can provide a key structural unit for the construction of many drug molecules. For example, some drugs with antibacterial and anti-inflammatory properties, imidazole-2-formaldehyde can be used as a starting material or a key intermediate in the synthesis process. Through specific chemical reactions, it is connected to other compounds to gradually build a drug molecular structure with specific pharmacological activities.
    Second, it also has important applications in the field of materials science. It can participate in the preparation of functional materials, such as some polymer materials with special optical and electrical properties. When it is introduced into the synthesis process of polymer, it can endow the material with unique properties, such as changing the absorption or emission characteristics of the material to specific wavelengths of light, or affecting the electrical conductivity of the material, so as to meet the needs of special functional materials in different fields.
    Third, in organic synthetic chemistry, imidazole-2-formaldehyde is often used as an important reagent. It can participate in a variety of classical organic reactions, such as condensation reactions with amine compounds to generate imine derivatives with potential biological activity or special structures. These derivatives can be used as multifunctional intermediates in further organic synthesis steps to derive more organic compounds with complex structures and unique properties, providing a rich material basis and reaction path for the development of organic synthetic chemistry.
    What are the physical properties of imidazole-2-carbaldehyde?
    Imidazole-2-carbalaldehyde is an organic compound with unique physical properties.
    It is mostly solid at room temperature. Due to the existence of various forces between molecules, the molecules are closely arranged and appear solid. Looking at its color, it is often white or off-white and has a pure appearance. This is related to the molecular structure and electron cloud distribution. Light reflection makes it appear this color.
    Imidazole-2-formaldehyde has a certain melting point and usually melts into a liquid within a specific temperature range. The melting point is determined by the intermolecular force. If the force is strong, the melting point will be high, and if it is weak, it will be low. And it has a certain solubility, soluble in some organic solvents such as ethanol and dichloromethane. Due to the principle of similarity and miscibility, its molecular structure has a certain similarity with the molecular structure of organic solvents, and can interact and dissolve. However, its solubility in water is limited, because its molecular polarity matches the polarity of water molecules poorly.
    In addition, it has a certain odor, although not strong and pungent, it can be perceived in a specific environment. This odor is sensed by the evaporation of molecules into the air and the interaction with olfactory receptors. And it has a certain stability and can be stored for a certain period of time under normal conditions. In case of changes in specific chemical reagents or environmental conditions, such as high temperature, strong acid and alkali, or chemical reactions, the structure changes.
    The common physical properties of this nemidazole-2-formaldehyde are of great significance to the fields of organic synthesis and medicinal chemistry, and are helpful to understand its reactivity and application characteristics.
    imidazole-2-carbaldehyde chemical synthesis methods
    Imidazole-2-formaldehyde, the synthesis method, has been known for a long time, and there are many ways now. In the past, when organic synthesis was first emerging, chemists used wisdom and ingenuity to explore the synthesis path of this compound.
    One method is also to introduce formyl groups based on imidazole under suitable reaction conditions. Imidazole can be combined with specific formylation reagents, such as N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl). Mix the two to form an active intermediate first, and then react with imidazole. When reacting, the temperature should be controlled moderately and should not be too high to avoid side reactions. The appropriate temperature is between 50 and 80 degrees Celsius, and the duration may be several hours or even a day, depending on the reaction process. After the reaction is completed, imidazole-2-formaldehyde can be obtained through separation and purification techniques, such as extraction, column chromatography, etc.
    Another method is derived from a specific heterocyclic synthesis strategy. Using small molecules containing nitrogen and carbon as raw materials, imidazole rings are constructed through multi-step reactions, and formyl groups are introduced at the second position at the same time. For example, glyoxal, ammonia and formamide are used as starting materials. First, through condensation reaction, the precursor of imidazole ring is formed, and then through oxidation and substitution, formyl groups are introduced at the second position of the ring. Although there are many steps in this process, the reaction conditions of each step are relatively mild and the yield is also good.
    Furthermore, with the advancement of science and technology, catalytic synthesis methods have gradually emerged. The use of metal catalysts, such as palladium, copper and other complexes, can catalyze specific substrates to generate imidazole-2-formaldehyde. This catalytic method has the advantages of high efficiency and good selectivity, but the preparation of catalysts and the control of reaction conditions are relatively high.
    imidazole-2-carbaldehyde in what areas?
    Imidazole-2-formaldehyde, this substance has extraordinary uses in many fields such as medicine and materials.
    In the field of medicine, it can be said to be a key intermediate for the preparation of many drugs. Taking some antifungal drugs as an example, imidazole-2-formaldehyde participates in the construction of the core structure of the drug. With its unique chemical structure, it can precisely combine with specific fungal targets, interfere with the normal physiological metabolism of fungi, and then exert anti-fungal effects.
    In the field of materials science, it also has important contributions. It can be used to synthesize polymer materials with special properties. After ingenious chemical reactions, imidazole-2-formaldehyde is introduced into the polymer skeleton, giving the material unique properties such as good thermal stability and excellent mechanical properties. These materials may be used in the aerospace field to manufacture key components of aircraft, because of their good performance to withstand extreme environments.
    In addition, in the field of organic synthesis, imidazole-2-formaldehyde is often used as an important starting material. Chemists can use various organic reactions to modify and derive organic compounds with diverse structures and functions, greatly enriching the variety of organic compounds and injecting vitality into the development of organic synthesis chemistry. In conclusion, although imidazole-2-formaldehyde is an organic compound, it plays a key role in many important fields and promotes the continuous development of various fields.
    What is the market price of imidazole-2-carbaldehyde?
    Imidazole-2-formaldehyde, the price of this product in the market, often changes for many reasons. Looking at the changes in market prices in the past, the abundance of raw materials, the cleverness of the process, and the urgency of demand are all the main factors that affect its price.
    If the raw materials are widely available, it is not difficult to obtain them, and their prices may stabilize, or even decline. However, if the raw materials are rare and difficult to obtain, the price will rise. Those with exquisite craftsmanship can have high yield, self-reduction in cost, and room for price reduction; on the contrary, if the craftsmanship is crude and the cost is high, the price will tend to be high. Furthermore, the demand in the market is urgent, and the supply is in short supply, so the price will jump; the demand is sluggish, and the stock of goods is in the market, and the price will decline.
    According to past market conditions, the price may fluctuate between tens of yuan and hundreds of yuan per kilogram. Recently, due to the situation of the chemical industry and the strictness of environmental protection regulations, the price has also changed. And different quality and purity, the price is also different. High purity, suitable for medicine, fine chemicals and other important places, the price is often high; ordinary purity, used for general chemical preparation, the price is slightly easier.
    For real-time market prices, when consulting chemical raw material suppliers, traders, or checking the quotation of commodity trading platforms, so that the exact price can be obtained.