Ethyl4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate/Imidazole Ester

Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate is 4- (1-hydroxy-1-methylethyl) -2-propyl imidazole-5-carboxylic acid ethyl ester, which imidazole esters have important uses in many fields.
In the field of pharmaceutical research and development, it may be a key intermediate. Through delicate chemical modification and transformation, novel drugs with specific pharmacological activities can be created. If its structure is ingeniously modified, or compounds that act on specific targets can be generated, providing new drug options for the treatment of diseases such as inflammation and tumors. Because the imidazole ring structure is widely found in many bioactive molecules, this imidazole ester can be used as a basic module for building complex active molecules, and through subsequent reactions, the final product is given precise biological activity and targeting.
In the field of materials science, the imidazole ester is also useful. It can participate in polymerization reactions and become a monomer for building special polymer materials. For example, copolymerization with other functional monomers may lead to the preparation of materials with unique electrical, optical or mechanical properties. The resulting polymer materials may exhibit extraordinary properties in the fields of electronic devices, optical sensors, etc., such as responsiveness to specific wavelengths of light, or unique electrical conductivity, thus meeting the strict requirements of different high-end technical fields for the special properties of materials.
In the field of organic synthetic chemistry, it is an extremely important synthetic building block. With its own functional group activity, it can participate in a variety of organic reactions, such as esterification, substitution, addition and other reactions. By rationally designing the reaction route, chemists can use it as a starting material to construct complex and diverse organic compounds, providing a rich material basis for the development of organic synthetic chemistry and helping chemists explore more novel chemical structures and reaction paths.

The synthesis of Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate/Imidazole Ester is an important matter in chemical synthesis. This synthesis path involves many techniques of organic synthesis, and the method may have the following ends.
First, a specific substituent can be introduced through an imidazole derivative as a starting material under suitable reaction conditions. First, the imidazole is reacted with a suitable halogenated hydrocarbon, which should contain the desired propyl structure, so that the imidazole ring can be connected to 2-propyl at a specific position. This reaction needs to be carried out in a suitable base and solvent environment to promote the occurrence of nucleophilic substitution reactions.
Second, for the introduction of 1-hydroxy-1-methylethyl structure at the fourth position of the imidazole ring, a suitable carbonyl compound can be used to react with organometallic reagents. If a suitable ketone is selected, it will react with organometallic reagents such as Grignard reagent or lithium reagent to generate a corresponding alcohol structure, thereby introducing 1-hydroxy-1-methylethyl.
Third, regarding the introduction of 5-carboxylic acid ethyl ester group, a suitable functional group can be constructed on the imidazole ring first, and then the carboxylic acid can be converted into ethyl ester group by means of esterification reaction. For example, imidazole derivatives containing carboxyl groups are first prepared, and then esterified with ethanol under acid catalysis to obtain the 5-carboxylic acid ethyl ester structure of the target product.
During the synthesis process, it is necessary to pay attention to the control of the reaction conditions at each step, such as temperature, reaction time, proportion of reactants, etc., which have a great impact on the yield and selectivity of the reaction. After each step of the reaction, separation and purification are often required to ensure the purity of the intermediate and facilitate the smooth progress of the subsequent reaction. All these are key steps and considerations in the synthesis of Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate/Imidazole Ester.

Ethyl 4- (1-hydroxy-1-methylethyl) - 2-propyl-imidazole-5-carboxylate/imidazole ester This compound belongs to organic compounds. Looking at its molecular structure, it contains imidazole rings and specific substituents, which makes it unique in physicochemical properties.
On its physical properties, at room temperature, or in a solid state, due to the considerable force between molecules. The melting boiling point also varies depending on the structure, containing polar hydroxyl groups and ester groups, increasing the attractive force between molecules, and the melting boiling point or non-low. However, the specific value needs to be carefully measured according to the experiment. Its solubility, due to its polar groups, may have a certain solubility in polar solvents, such as alcohols and ketones; in non-polar solvents, such as alkanes, the solubility may be poor.
As for chemical properties, imidazole rings are electron-rich and easily involved in electrophilic substitution reactions. Under appropriate conditions, they can react with electrophilic reagents to generate new derivatives. Its ester groups can be hydrolyzed, and the hydrolysis rates are different in acidic or basic environments. In alkaline environments, hydrolysis or speed, carboxylic salts and alcohols are generated; under acidic conditions, hydrolysis is slow and reversible to produce carboxylic acids and alcohols. Hydroxyl groups are also active and can participate in esterification, oxidation and other reactions. Under suitable oxidation conditions, they can be oxidized to carbonyl groups. And because the structure contains multiple active check points, or can be used as a key intermediate in organic synthesis, through various reactions, complex organic molecules can be constructed.

Ethyl 4- (1 - Hydroxy - 1 - Methylethyl) -2 - Propyl - Imidazole - 5 - Carboxylate/Imidazole Ester (4 - (1 - Hydroxy - 1 - Methylethyl) -2 - Propylimidazole - 5 - Ethyl Carboxylate/Imidazole Ester) is a relatively uncommon chemical. On the market, its price range is influenced by many factors.
First, the cost of raw materials for preparing this compound has a significant impact. If the starting materials required for preparation are scarce and expensive, or the acquisition process is complicated and requires multi-step reaction and purification, then the cost of the product will be high and the price will rise accordingly.
Second, the difficulty and complexity of the synthesis process are also key factors. If the synthesis route is lengthy, involves special reaction conditions, such as high temperature, high pressure, specific catalysts, or requires a strict anhydrous and anaerobic environment, the process cost will increase, and the price will be high.
Third, the following pairs of market demand and supply have a significant impact on the price. If this compound is widely used in medicine, materials and other fields, the demand is strong, and the manufacturer is limited, the supply is insufficient, and the price will naturally rise; on the contrary, if the demand is flat and the production is excessive, the price will be reduced.
Fourth, the purity of the product also affects the price. High-purity products are difficult to prepare, expensive, and the price is much higher than that of low-purity products.
However, because I do not know the current specific market conditions, it is difficult to specify its price range. Generally speaking, in the fine chemical raw material market, the price of such relatively niche and difficult compounds may fluctuate from tens of yuan to hundreds of yuan per gram. This is only a rough guess, and the actual price should be subject to the specific market quotation.

Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate is 4- (1-hydroxy-1-methylethyl) -2-propyl imidazole-5-carboxylate ethyl ester, often referred to as imidazole ester. This substance is related to safety and toxicity, and cannot be ignored.
Looking at its safety properties, this substance is stable under specific conditions. However, in case of hot topic, open flame or strong oxidant, it may cause unexpected changes. Therefore, when storing, it should be placed in a cool and ventilated place, away from fire and heat sources, and should be stored separately from oxidants, and must not be mixed with storage to prevent accidents. During the operation, the operator should strictly follow the operating procedures, wear appropriate protective equipment, such as protective glasses, gloves and protective clothing, etc., to avoid direct contact with the skin and eyes. In case of inadvertent contact, rinse immediately with plenty of water and seek medical treatment in time.
As for toxicity, studies have shown that its acute toxicity is relatively low. Even so, it should not be taken lightly. Long-term or repeated exposure may damage the body. Animal experiments have shown that high doses of exposure may affect the function of organs such as the liver and kidneys. And it has a certain irritation to the skin and eyes, which can cause skin redness, itching, eye tingling, tears and other symptoms. In addition, due to the characteristics of its chemical structure, it may have a certain persistence and bioaccumulation in the environment, and may pose a potential threat to the ecological environment.
In summary, although Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate appears to be stable under normal conditions, its safety and toxicity are like thorns hidden in the dark. It must be treated with caution and cannot be slack to prevent personal harm and environmental safety.